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Spontaneous pneumomediastinum in a patient with bronchiolitis obliterans after bone marrow transplantation

Bone Marrow Transplantation volume 20, pages 695–696 (1997)Cite this article

Abstract

After allogeneic bone marrow transplantation for chronic myelogenous leukemia, spontaneous pneumomediastinum and subcutaneous emphysema developed in a patient with bronchiolitis obliterans. Computed tomography scanning of the chest failed to reveal the cause. There was no evidence of a pulmonary process, pneumothorax, or pharyngeal or upper airway leak. Despite the alarming appearance of the patient, conservative management, including high-flow oxygen, resulted in resolution of the pneumomediastinum and subcutaneous emphysema. The cause of pneumomediastinum and subcutaneous emphysema in bone marrow transplant recipients is discussed.

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Authors and Affiliations

  1. Division of Hematology and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN, USA

    E Galanis, MR Litzow & A Tefferi

  2. Division of Pulmonary and Critical Care Medicine and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN, USA

    JP Scott

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  1. E Galanis
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  2. MR Litzow
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  3. A Tefferi
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  4. JP Scott
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Galanis, E., Litzow, M., Tefferi, A. et al. Spontaneous pneumomediastinum in a patient with bronchiolitis obliterans after bone marrow transplantation. Bone Marrow Transplant 20, 695–696 (1997). https://doi.org/10.1038/sj.bmt.1700939

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  • DOI: https://doi.org/10.1038/sj.bmt.1700939

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