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Neosartorya fischeri: an invasive fungal pathogen in an allogeneic bone marrow transplant patient

Abstract

Invasive fungal infections are a complication of allogeneic BMT. We report the first case of a Neosartorya fischeri fungal infection in a patient following allogeneic BMT. Neosartorya fischeri is related to Aspergillus fumigatus, but it is a distinct fungal species. Despite granulocytic engraftment and aggressive anti-fungal therapy with amphotericin B, the patient died of overwhelming fungal infection on day 60 post-BMT. Neosartorya fischeri is a pathogen that grows slowly in culture which can delay or confuse identification. This case further supports the need for more effective prophylaxis and treatment of non-Candida fungal infections in the allogeneic BMT population.

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Lonial, S., Williams, L., Carrum, G. et al. Neosartorya fischeri: an invasive fungal pathogen in an allogeneic bone marrow transplant patient. Bone Marrow Transplant 19, 753–755 (1997). https://doi.org/10.1038/sj.bmt.1700715

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  • DOI: https://doi.org/10.1038/sj.bmt.1700715

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