Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Original Communication
  • Published:

Use of energy-dense formula for treating infants with non-organic failure to thrive

Abstract

Objective: To evaluate if simply increasing the energy density of the formula will lead to increased energy intake and weight gain in infants with non-organic failure to thrive.

Design: In this hospital-based trial, 15 infants (mean age, 7.6±1.4 months) with non-organic failure to thrive were fed a regular strength formula (2.8 kJ/ml) for 3 days and then switched to the same formula with a higher energy density (4.18 kJ/ml) for 3 days after a 2 day ‘wash-out’ period. Daily nude weights and energy intakes were recorded for the two 3 day periods.

Results: During feeding with the higher density formula, nine (60%) infants had a significant increase in their energy intake and weight gain (both P<0.02); four (27%) showed no change in energy intake and self-regulated their intake by decreasing the volume of feeds consumed to maintain energy intake; and two (13%) infants consumed a significantly reduced amount of energy (P<0.02).

Conclusion: Increasing the energy density of the formula may provide a useful intervention to increase the weight gain and energy intake of most infants with non-organic failure to thrive.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  • Berwick D, Levy J, Kleinerman R . 1982 Failure to thrive: diagnostic yield of hospitalization Arch. Dis. Child. 57: 347–351

    Article  CAS  Google Scholar 

  • English P . 1978 Failure to thrive without organic reason Pediatr. Ann. 7: 774–781

    CAS  PubMed  Google Scholar 

  • Fomon SJ . 1974 Normal growth, failure to thrive and obesity In: Infant nutrition Philadelphia, PA: WB Saunders

    Google Scholar 

  • Fomon SJ, Filer LJ Jr, Thomas LN, Rogers RR, Proksch AM . 1969 Relationship between formula concentration and rate of growth of normal infants J. Nutr. 98: 241–254

    Article  CAS  Google Scholar 

  • Homer C, Ludwig S . 1981 Categorization of etiology of failure to thrive Am. J. Dis. Child. 135: 848–851

    CAS  PubMed  Google Scholar 

  • Sills RH . 1978 Failure to thrive: the role of clinical and laboratory evaluation Am. J. Dis. Child. 132: 967–969

    Article  CAS  Google Scholar 

  • Wright P . 1987 Hunger, satiety and feeding behaviour in early infancy In: Eating Habits: Food, Physiology and Learned Behaviour Chichester: Wiley

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to V Khoshoo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Khoshoo, V., Reifen, R. Use of energy-dense formula for treating infants with non-organic failure to thrive. Eur J Clin Nutr 56, 921–924 (2002). https://doi.org/10.1038/sj.ejcn.1601406

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.ejcn.1601406

Keywords

Search

Quick links