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Depression of the glycemic index by high levels of β-glucan fiber in two functional foods tested in type 2 diabetes

European Journal of Clinical Nutrition volume 56, pages 622–628 (2002)Cite this article

Abstract

Objectives: To determine the extent to which β-glucan reduces the glycemic index (GI) of oat products and whether high levels of β-glucan impair palatability.

Design: The study design was an open-label, randomized cross-over study with six treatment segments.

Setting: Free-living outpatients.

Subjects: Sixteen volunteers with type 2 diabetes (10 men, six women, 61±2 y, body mass index 29±2 kg/m2, HbA1c 7.4±0.4%) were recruited from the St Michael's Hospital diabetes clinic.

Interventions: Volunteers were given, in random order, 50 g available carbohydrate portions of: white bread; a commercial oat bran breakfast cereal (4.4 g% β-glucan); and a prototype β-glucan-enriched breakfast cereal and bar, both high in β-glucan (8.1 and 6.5 g% β-glucan, respectively) and sweetened with fructose. Capillary blood samples were taken fasting and then 30, 60, 90, 120, 150 and 180 min after the start of the meal. Palatability was recorded using two different methods.

Results: The glycemic indices of the prototype β-glucan cereal (mean±s.e.m.; 52±5) and β-glucan bar (43±4.1) were significantly lower than the commercial oat bran breakfast cereal (86±6) and white bread (100; P<0.05). All foods were highly palatable and not significantly different. It was found that the GI of the test foods used in this study decreased by 4.0±0.2 units per gram of β-glucan compared to our estimate of 3.8±0.6 for studies reported in the literature.

Conclusion: Addition of β-glucan predictably reduces the GI while maintaining palatability. In a 50 g carbohydrate portion each gram of β-glucan reduces the GI by 4 units, making it a useful functional food component for reducing postprandial glycemia.

Sponsorship: Nestec, Switzerland.

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Author notes

  1. V Vuksan: Guarantor: Dr V Vuksan.

  2. AL Jenkins, DJA Jenkins, U Zdravkovic, P Würsch and V Vuksan: Contributors: AJ was involved in the day-to-day running of the study, study recruitment, data analysis and preparation of the manuscript. DJ contributed to the initial design of the study, supplied the laboratory facilities and was involved in writing the paper; UZ was responsible for the drawing of samples, laboratory analysis and patient care; PW was responsible for the product development and supply, and design of the protocol; VV was involved in the design of the study, supervision of the running of the study, including laboratory analysis and writing of the paper.

Authors and Affiliations

  1. Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, Canada

    AL Jenkins, DJA Jenkins, U Zdravkovic & V Vuksan

  2. Department Nutritional Sciences, University of Toronto, Toronto, Canada

    DJA Jenkins & V Vuksan

  3. Nestlé Product Technology Centre, Orbe, Switzerland

    P Würsch

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  1. AL Jenkins
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Jenkins, A., Jenkins, D., Zdravkovic, U. et al. Depression of the glycemic index by high levels of β-glucan fiber in two functional foods tested in type 2 diabetes. Eur J Clin Nutr 56, 622–628 (2002). https://doi.org/10.1038/sj.ejcn.1601367

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Keywords

  • β-glucan fiber
  • glycemic index
  • oat bran
  • fructose
  • functional foods
  • nutraceuticals

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