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Agarwal A, Williams GH, Fisher ND . Genetics of human hypertension. Trends Endocrinol Metab 2005; 16: 127–133.
Sesso DH, Buring JE, Nader R, Blake GJ, Gaziano JM, Ridker PM . C reactive protein and risk of developing hypertension. JAMA 2003; 290: 2945–2951.
Grundy SM . Inflammation, hypertension and metabolic syndrome. JAMA 2003; 290: 3000–3002.
Huang G, Niu T, Peng S, Ling D, Liu J, Zhang X et al. Association between the interleukin-1beta C(-511)T polymorphism and blood pressure in a Chinese hypertensive population. Immunol Lett 2004; 91: 159–162.
Francis SE, Camp NJ, Dewberry RM, Gunn J, Syrris P, Carter ND et al. Interleukin-1 receptor antagonist gene polymorphism and coronary artery disease. Circulation 1999; 99: 861–866.
Lin RC, Morris BJ . Association analysis of polymorphisms at the interleukin-1 locus in essential hypertension. Am J Med Genet 2002; 107: 311–316.
Pakistan Medical Research Council. National Health Survey of Pakistan 1990–94. Pakistan Medical Research Council, Network Publication Service: Islamabad, Pakistan, 1998.
Tarlow JK, Blakemore AI, Lennard A, Solari R, Hughes HN, Steinkasserer A et al. Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat. Hum Genet 1993; 91: 403–404.
Ross R . Atherosclerosis – an inflammatory disease. N Engl J Med 1999; 340: 115–126.
Ridker PM, Hennekens CH, Buring JE, Rifai N . C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease. N Engl J Med 2000; 342: 836–843.
Schwartz RS, Bayes-Genis A, Lesser JR, Sangiorgi M, Henry TD, Conover CA . Detecting vulnerable plaque using peripheral blood: inflammatory and cellular markers. J Interv Cardiol 2003; 16: 231–242.
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Khawaja, M., Taj, F., Saleheen, D. et al. Association study of two interleukin-1 gene loci with essential hypertension in a Pakistani Pathan population. J Hum Hypertens 22, 60–62 (2008). https://doi.org/10.1038/sj.jhh.1002257