Abstract
OBJECTIVE: To examine the changes in intake of fruits and vegetables in relation to risk of obesity and weight gain among middle-aged women.
DESIGN: Prospective cohort study with 12 y of follow-up conducted in the Nurses' Health Study.
SUBJECTS: A total of 74 063 female nurses aged 38–63 y, who were free of cardiovascular disease, cancer, and diabetes at baseline in 1984.
MEASUREMENTS: Dietary information was collected using a validated food frequency questionnaire, and body weight and height were self-reported.
RESULTS: During the 12-y follow-up, participants tended to gain weight with aging, but those with the largest increase in fruit and vegetable intake had a 24% of lower risk of becoming obese (BMI≥30 kg/m2) compared with those who had the largest decrease in intake after adjustment for age, physical activity, smoking, total energy intake, and other lifestyle variables (relative risk (RR), 0.76; 95% confidence interval (CI), 0.69–0.86; P for trend <0.0001). For major weight gain (≥25 kg), women with the largest increase in intake of fruits and vegetables had a 28% lower risk compared to those in the other extreme group (RR, 0.72; 95% CI, 0.55–0.93; P=0.01). Similar results were observed for changes in intake of fruits and vegetables when analyzed separately.
CONCLUSIONS: Our findings suggest that increasing intake of fruits and vegetables may reduce long-term risk of obesity and weight gain among middle-aged women.
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References
US Department of Agriculture, US Department of Health and Human Services. Nutrition and your health: dietary guidelines for Americans. US Government Printing Office: Washington, DC; 1995.
Krauss RM, Deckelbaum RJ, Ernst N, Fisher E, Howard BV, Knopp RH, Kotchen T, Lichtenstein AH, McGill HC, Pearson TA, Prewitt TE, Stone NJ, van Horn L, Weinberg R . Dietary guidelines for healthy American adults. A statement for health professionals from the Nutrition Committee, American Heart Association. Circulation 1996; 94: 1795–1800.
Joshipura KJ, Hu FB, Manson JE, Stampfer MJ, Rimm EB, Speizer FE, Colditz G, Ascherio A, Rosner B, Spiegelman D, Willett WC . The effect of fruits and vegetable intake on risk for coronary heart disease. Ann Intern Med 2001; 134: 1106–1114.
Liu S, Manson JE, Lee IM, Cole SR, Hennekens CH, Willett WC, Buring JE . Fruits and vegetable intake and risk of cardiovascular disease: the Women's Health Study. Am J Clin Nutr 2000; 72: 922–928.
Ford ES, Mokdad AH . Fruits and vegetable consumption and diabetes mellitus incidence among U.S. adults. Prev Med 2001; 32: 33–39.
Newby PK, Muller D, Hallfrisch J, Qiao N, Andres R, Tucker KL . Dietary patterns and changes in body mass index and waist circumference in adults. Am J Clin Nutr 2003; 77: 1417–1425.
Togo P, Osler M, Sorensen TIA, Heitmann BL . A longitudinal study of food intake patterns and obesity in adult Danish men and women. Int J Obes Relat Metab Disord 2004; 28: 583–593.
Togo P, Osler M, Sorensen TIA, Heitmann BL . Food intake patterns and body mass index in observational studies. Int J Obes Relat Metab Disord 2001; 25: 1741–1751.
Smith SA, Campbell DR, Elmer PJ, Martini MC, Slavin JL, Potter JD . The University of Minnesota Cancer Prevention Research Unit vegetable and fruits classification scheme (United States). Cancer Causes Control 1995; 6: 292–302.
Willett WC, Sampson L, Stampfer MJ, Rosner B, Bain C, Witschi J, Hennekens CH, Speizer FE . Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 1985; 122: 51–65.
Salvini S, Hunter DJ, Sampson L, Stampfer MJ, Colditz GA, Rosner B, Willett WC . Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol 1989; 18: 858–867.
Willett WC, Stampfer MJ, Bain C, Lipnick R, Speizer FE, Rosner B, Cramer D, Hennekens CH . Cigarette smoking, relative weight, and menopause. Am J Epidemiol 1983; 117: 651–658.
Liu S, Willett WC, Manson JE, Hu FB, Rosner B, Colditz G . Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women. Am J Clin Nutr 2003; 78: 920–927.
Willett WC . Nutritional epidemiology, 2nd edn. Oxford University Press: New York; 1998.
Joshipura KJ, Ascherio A, Manson JE, Stampfer MJ, Rimm EB, Speizer FE, Hennekens CH, Spiegelman D, Willett WC . Fruits and vegetable intake in relation to risk of ischemic stroke. JAMA 1999; 282: 1233–1239.
Serdula MK, Byers T, Mokdad AH, Simoes E, Mendlein JM, Coates RJ . The association between fruits and vegetable intake and chronic disease risk factors. Epidemiology 1996; 7: 161–165.
Epstein LH, Gordy CC, Raynor HA, Beddome M, Kilanowski CK, Paluch R . Increasing fruits and vegetable intake and decreasing fat and sugar intake in families at risk for childhood obesity. Obes Res 2001; 9: 171–178.
Singh RB, Niaz MA, Ghosh S . Effect on central obesity and associated disturbances of low-energy, fruits- and vegetable-enriched prudent diet in north Indians. Postgrad Med J 1994; 70: 895–900.
Burton-Freeman B . Dietary fiber and energy regulation. J Nutr 2000; 130 (2S Suppl): 272S–275S.
Pereira MA, Ludwig DS . Dietary fiber and body-weight regulation. Observations and mechanisms. Pediatr Clin North Am 2001; 48: 969–980.
Bell EA, Castellanos VH, Pelkman CL, Thorwart ML, Rolls BJ . Energy density of foods affects energy intake in normal-weight women. Am J Clin Nutr 1998; 67: 412–420.
Steptoe A, Perkins-Porras L, McKay C, Rink E, Hilton S, Cappuccio FP . Behavioural counseling to increase consumption of fruit and vegetables in low income adults: randomized trial. BMJ 2003; 326: 855–860.
Hu FB, Li TY, Colditz GA, Willett WC, Manson JE . Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA 2003; 289: 1785–1791.
Acknowledgements
This work was supported by the research grant CA87969 from the National Institutes of Health. We are indebted to the participants of the Nurses' Health Study for their continuing participation and cooperation.
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He, K., Hu, F., Colditz, G. et al. Changes in intake of fruits and vegetables in relation to risk of obesity and weight gain among middle-aged women. Int J Obes 28, 1569–1574 (2004). https://doi.org/10.1038/sj.ijo.0802795
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DOI: https://doi.org/10.1038/sj.ijo.0802795
Keywords
- fruits and vegetables
- weight gain
- prospective study
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