Vimentin tunes cell stress by assisting in both actomyosin force transmission and reinforcement of microtubule networks under compression. The competition between these two opposing effects of vimentin is regulated by the microenvironment stiffness.

This review discusses recent advances demonstrating the role of replication stress as an ultimate driver of cellular senescence and aging, highlighting connections to hallmarks of aging, hereditary accelerated aging disorders, and senotherapeutics.

Infant gray mouse lemurs performed better when they were born to mothers fed with dairy fat vs. vegetable fat in a set of tasks involving motor synchronization, sensory perception, learning and memory, suggesting an earlier psychomotor and cognitive development.

A DADA2 zebrafish model with cecr1b deficiency was generated. Characterization of hematopoietic processes revealed a role of Cecr1b in regulating inflammation and hematopoietic stem cell production through the A_2br-mediated adenosine signaling.

Current methods quantifying phage lytic efficacy have limits. Centroid Index quantifies efficacy via the center of area, offering more accuracy. For calculation of this index, a software called Centroid Index Calculator is presented.

Cryo-EM structure of human ATP-binding cassette transporter 6 (ABCB6) in complex with Cd(II) and glutathione (GSH) provides molecular insight into its dual role, essential for heme biosynthesis and as a heavy metal efflux pump.

IDO downregulation in dMDSCs induced by Toxoplasma gondii infection regulates expression of TGF-β and IL-10 through the Kyn/AhR/SP1 signal pathway, eventually contributing to the dysfunction of dNK cells.

A customized and shielded street lighting design significantly reduces the lethal attraction of flying insects in various environments. The approach harmonizes human needs with minimizing the ecological impact of artificial light at night.

A study on early life traumatic stress in mice suggest that changes in the fecal microbial community induced by early life stress can be perpetuated from exposed parent to the offspring across two generations.

Single-cell atlas of Microhyla fissipes lungs reveals cell differentiation and functionalization during metamorphosis, further cross-species comparison sheds light vertebrate lung cell type evolution.

This comment reports on work done at Harvard Medical School to identify areas for improvement in research rigor, reproducibility, and responsibility in pursuit of continued research excellence.

Documentation of women’s inclusion in Indian academia and conferences by BiasWatchIndia reveals the scale of underrepresentation of women across science, technology, engineering and mathematics.

In 2023, we conducted a virtual program to introduce early-career researchers to the fundamentals of academic journal editing. Here, we reflect on the mission of this program and its outcomes.

A comment article summarizing a range of research activities that contribute to understanding evolving Māori perspectives on Gene Editing and how they might contribute to future regulation.

Nanoparticle therapy continues to be an attractive avenue of targeted and personalised therapies. A molecular nano-conjugate developed by Zeng et al. effectively targets cancer cells and aids in their diagnosis, therapy, and also optimises innate immune responses.