One benefit of studying mice is that most of their genes have counterparts in humans. Two groups have used this similarity to study when and where the genes found on human chromosome 21 are switched on.
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References
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The HSA21 expression map initiative Nature 420, 586–590 (2002).
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Reeves, R. A time and place for every gene. Nature 420, 518–519 (2002). https://doi.org/10.1038/420518a
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DOI: https://doi.org/10.1038/420518a