Thioredoxins

Definition

Thioredoxins are small enzymes that play a role in cellular redox systems by facilitating reduction of other proteins via their dithiol-disulphide active site. Thioredoxins act as antioxidants that reduce oxidative stress and other environmental stresses, protect proteins from oxidative aggregation and inactivation to promote protein folding, regulate apoptosis via denitrosylation, and modulate inflammation.

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