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Tonic and burst-like locus coeruleus firing distinctly tune brain topology toward associative and sensory regions, recruiting both astrocytic and neuronal inhibitory activity.
Early environmental factors, like disadvantage, are associated with neurocognitive development. Here, the authors find that neonates and toddlers from economically disadvantaged backgrounds show accelerated brain development, with implications for language abilities in toddlerhood.
Resistance to stress is vital for survival. Here the authors identify a group of anxiolytic NPY(NPYDRN/vlPAG) neurons that alleviate stress-induced hypophagia and anxiety, revealing a feedforward inhibition mechanism underlying stress resistance.
Increased levels of matrix metalloproteinase 8, expressed by circulating myeloid cells, may have a role in stress-induced changes in social behaviour in mice.
Two articles in Nature Reviews Psychology propose a resilience-based approach to mental health outcomes that shifts attention from a binary view of psychopathology to diversity.