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Oral squamous cell carcinoma is a prevalent malignancy in Taiwan. Here, the authors show that OSCC in Taiwanese show a frequent deletion polymorphism in the cytidine deaminases gene cluster APOBEC3 resulting in increased expression of A3A, which is shown to be of clinical prognostic relevance.
There's no escaping the escalating rates of head and neck cancers we've seen over the last decade, and that will inevitably lead to an expansion in the role of the dental professional over time. David Westgarth speaks to Professor Simon Rogers at Aintree University Hospital about what it takes to succeed as an oral and maxilliofacial surgeon.