Intrinsically disordered proteins articles within Nature Physics

Featured

  • Article |

    The protein VASP can undergo liquid–liquid phase separation. The interplay between the surface tension of the VASP droplet and actin polymerization controls the bundling of actin filaments, a necessary step for many cellular processes.

    • Kristin Graham
    • , Aravind Chandrasekaran
    •  & Jeanne C. Stachowiak
  • News & Views |

    Biomolecular condensates grow in busy cellular environments. Statistical image analysis of heterogeneous structures now enables quantification of macromolecular interactions between condensates and cytoskeletal filaments.

    • Tina Wiegand
    •  & Arjun Narayanan
  • Progress Article |

    The internal structure of cells is organized into compartments, many of which lack a confining membrane and instead resemble viscous liquid droplets. Evidence is mounting that these compartments form via spontaneous phase transitions.

    • Clifford P. Brangwynne
    • , Peter Tompa
    •  & Rohit V. Pappu