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Intracellular recording is an electrophysiology technique that uses a microelectrode inserted into a single cell, usually a neuron, to measure its electrical activity.
An electronic interface with 4,096 electrodes can intracellularly record postsynaptic potentials and action potentials from thousands of connected mammalian neurons in vitro.
Chen, Cang and colleagues describe how to characterize intracellular ion channels using a manual patch-clamp technique on enlarged organelles such as endolysosomes.
