Hepatocyte growth factor

Definition

Hepatocyte growth factor is a protein secreted by mesenchymal stem cells that regulates cell growth, cell motility and morphogenesis of epithelial cells, endothelial cells, and haematopoietic stem cells, through its receptor, c-Met. Signalling downstream of c-Met leads to cell identity changes that take place during organ development, angiogenesis and other morphogenesis processes.

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