Method to Watch |
Featured
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Article |
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
O-Pair search identifies O-glycopeptides and localizes O-glycosites using a fragment-ion-indexed open modification search combined with a graph-based approach. It also introduces a classification scheme to unify data reporting for glycoproteomics.
- Lei Lu
- , Nicholas M. Riley
- & Lloyd M. Smith
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Article |
Fast and comprehensive N- and O-glycoproteomics analysis with MSFragger-Glyco
MSFragger-Glyco allows identification of N- and O-linked glycopeptides using the localization-aware open search strategy of the MSFragger search engine.
- Daniel A. Polasky
- , Fengchao Yu
- & Alexey I. Nesvizhskii
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Research Highlight |
Selective cell-surface N-glycan editing
A two-step chemoenzymatic method for N-glycan subtype-selective editing.
- Arunima Singh
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Article |
Glyco-DIA: a method for quantitative O-glycoproteomics with in silico-boosted glycopeptide libraries
O-glycopeptides and O-glycan structures can be identified and quantified on a proteome-wide scale with Glyco-DIA, a data-independent-acquisition mass spectrometry-based method.
- Zilu Ye
- , Yang Mao
- & Sergey Y. Vakhrushev
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Methods in Brief |
Comprehensive glycoprotein characterization
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Research Highlights |
Constructing complicated carbohydrates
A stepwise strategy of targeted synthesis enables researchers to reconstruct cellular glycomes in vitro.
- Michael Eisenstein
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Methods in Brief |
Binders of O-glycosylated proteins
Glycoproteomics