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Fungal physiology is a scientific discipline that concerns the life-supporting functions and processes of fungi that allow fungal organisms to grow and reproduce.
The authors uncover the molecular mechanisms through which the arginine methyltransferase PRMT5 regulates the biosynthesis of secondary metabolites in the fungus Ganoderma lucidum.
Pipercevic et al resolve how inositol molecules activate the VTC protein complex. The VTC complex stores phosphate in yeast and is controlled by SPX domains. The inositol molecules break an interaction between SPX domains to activate the complex.
This study reports that mycobiota-derived metabolites can feed pathogenic Salmonella enterica subsp. enterica serovar Typhimurium and promote its competitive advantage, thus revealing a role of the fungal community during bacterial infection.