Novel osteoanabolic strategies are highly desired to treat osteoporotic bone loss or augment fracture repair in patients at risk of healing complications, including individuals with osteoporosis or inflammatory disorders. Whereas current osteoanabolics address osteoblast function, research by Ren Xu and colleagues highlights the skeletal endothelium as a promising target to promote bone formation.
- Anita Ignatius
- Jan Tuckermann