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The genetic architecture underlying rapid phenotypic changes remains largely unknown. Here, the authors show that genes with an intermediate degree of pleiotropy have the highest rate of adaptive evolution in Arabidopsis thaliana.
Genomic analysis of Salmonella Enteritidis isolates taken from a single individual with a chronic and relapsing infection reveals how these bacteria have adapted to their host surroundings. Increased within-host fitness comes at the expense of ancillary traits such as virulence.