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Neuronal influence on peripheral circadian oscillators in pupal Drosophila prothoracic glands
In the fruit flyDrosophila, changes in expression of circadian clock genes are believed to control eclosion. Morioka and colleagues show that transcriptional oscillations of the clock gene, period, in prothoracic gland cells are amplified by photic inputs from the central nervous system.
- Eri Morioka
- , Akira Matsumoto
- & Masayuki Ikeda
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| Open Access
Evidence for the stress-linked immunocompetence handicap hypothesis in humans
Testosterone-dependent traits are thought to give an honest signal of male immune function, however, the exact effects remain unclear. This study shows a positive relationship between testosterone, facial attractiveness and the immune response to a hepatitis B vaccine, which is moderated by naturally co-occurring cortisol.
- Markus J. Rantala
- , Fhionna R. Moore
- & Indrikis Krams
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Existence of long-lasting experience-dependent plasticity in endocrine cell networks
Experience-dependent plasticity and functional adaptation are thought to be restricted to the central nervous and immune systems. This study shows that long-lasting experience-dependent plasticity is a key feature of endocrine cell networks, allowing improved tissue function and hormone output following repeat demand.
- David J. Hodson
- , Marie Schaeffer
- & Patrice Mollard
Molecular mechanics of mineralized collagen fibrils in bone