Drug screening articles within Nature Materials

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• Review Article | 17 August 2020

  Somatic cell-derived organoids as prototypes of human epithelial tissues and diseases

  This Review highlights approaches used to generate somatic cell-derived organoids for modelling epithelial tissue to understand disease progression and how they are employed in preclinical drug screening.

  • Masayuki Fujii
  •  & Toshiro Sato

• Article | 27 April 2020

  A year-long extended release nanoformulated cabotegravir prodrug

  Nanoformulated long-acting cabotegravir prodrugs are shown to be capable of extending the native drug’s antiretroviral activity, biodistribution and pharmacokinetics for up to 12 months in mice and rhesus macaques.

  • Tanmay A. Kulkarni
  • , Aditya N. Bade
  •  & Howard E. Gendelman