Diabetes complications

Diabetes complications are disorders that arise as a result of the patient having diabetes. The high blood sugar levels that often present in patients with diabetes cause damage to various tissues and organs, which increases the risk of cardiovascular disease and can result in disorders such as diabetic retinopathy.

Latest Research and Reviews

News and Comment

  • News and Views |

    New findings implicate sodium transport in α-cell secretory dysfunction, leading to impaired counter-regulatory responses in diabetes. However, these findings also raise important questions about the tissue-specific roles of sodium transport and suggest that inhibitors of sodium transport may have potentially divergent roles in the pancreas, kidney and heart.

    • Julie A. Lovshin
    •  & David Z. Cherney
  • News and Views |

    Detailed profiles of fluctuations in glucose obtained via continuous glucose monitoring highlight the complexity of glucose regulation and underscore that the definition of type 2 diabetes mellitus as a homogeneous disease is an oversimplistic approximation for a heterogeneous metabolic disorder. Whether better phenotyping would ultimately result in improved interventions and outcomes, however, remains largely unproven.

    • Francesco Zaccardi
    •  & Kamlesh Khunti
  • News and Views |

    Hypoglycaemia-induced morbidity and mortality has emerged as one of the major unintended consequences of efforts to achieve optimal glucose control in individuals with insulin-treated diabetes mellitus. A study by Jackson and colleagues offers novel insights into therapies to mitigate the adverse consequences hypoglycaemic events have on the central nervous system.

    • Janice J. Hwang
    •  & Robert S. Sherwin