Featured
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Article |
Molecular motors robustly drive active gels to a critically connected state
A study of an actomyosin active gel now demonstrates the importance of the crosslinking density of actin polymers in enabling myosin motors to internally drive contraction and rupture the network into clusters. These results could help us to better understand the role of the cytoskeleton in cell division and tissue morphogenesis.
- José Alvarado
- , Michael Sheinman
- & Gijsje H. Koenderink
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News & Views |
Focus amidst the noise
High-resolution imaging of neuronal networks reveals that spontaneous bursts of collective activity are a consequence of an implosive concentration of noise.
- John M. Beggs
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Article |
Noise focusing and the emergence of coherent activity in neuronal cultures
Neuronal networks can spontaneously exhibit periodic bursts of collective activity. High-resolution calcium imaging and computer modelling of in vitro cultures now reveal that this behaviour is a consequence of noise focusing—an implosive concentration of spontaneous activity due to the interplay between network topology and intrinsic neuronal dynamics.
- Javier G. Orlandi
- , Jordi Soriano
- & Jaume Casademunt