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Cellular neuroscience is the study of neurons at the cellular level. It includes cell morphology and physiological properties such as membrane trafficking, synthesis and transport of proteins, and synaptic plasticity.
Head direction is encoded by cells in the presubiculum, but the role of local circuitry in head direction encoding remains unknown. Here the authors demonstrate how a specific inhibitory neuron type, the Martinotti cell, together with excitatory pyramidal cells supports head direction signals.
Addictive substances hijack the reward system partly via synaptic plasticity onto dopamine neurons. Cadherins may contribute to cocaine-evoked adaptations, supporting the notion that drug addiction is a synaptic disease.
Grid-firing fields of neurons in the entorhinal cortex are thought to require inputs encoding running speed. Glutamatergic projections from the medial septum may be one of the inputs that provide these speed signals.