Cancer prevention

Cancer prevention includes treatments, procedures and lifestyle changes that aim to reduce the risk that cancer will develop in an individual. Some cancer prevention strategies are well known and government-funded; for example, stopping smoking, eating a healthy diet and undergoing a specific screening procedure, such as mammography.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    Perioperative chemotherapy is the standard of care for localized gastric cancer (GC). In 2018, additional postoperative radiotherapy was found to be ineffective; although, docetaxel was found to be superior to epirubicin in perioperative three-drug chemotherapy regimens. Validated biomarkers are needed for benefit from immunotherapy in advanced-stage GC. Metachronous GC can be prevented by Helicobacter pylori eradication.

    • Florian Lordick
    •  & Elizabeth C. Smyth
  • News and Views |

    Chemoprevention for patients with Barrett’s oesophagus remains a controversial topic. Results of the first randomized trial of chemoprevention using a proton pump inhibitor with or without aspirin were recently reported. We highlight strengths and weaknesses in the design of the trial and discuss the clinical implications of the findings.

    • Nisreen S. Husain
    •  & Hashem B. El-Serag
  • News and Views |

    Population-based mammographic screening is widely accepted as an intervention to reduce overall mortality from breast cancer, but at the cost of morbidity due to false positives and substantial overdiagnosis and overtreatment of ultra-low-risk disease, as well as personal and health-economic burdens. Recent data from a modelling study strengthen the rationale for personalized, risk-based screening approaches, now being tested in multiple clinical trials.

    • Laura J. Esserman
    •  & Andrea Z. LaCroix