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News & Views |
Orbicular origins
The application of imaging techniques prevalent in materials science to the biological process of soft tissue calcification lends new insight into age-related cardiovascular disease.
- Jordan D. Miller
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Article |
Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification
Analytical techniques reveal that spherical calcium phosphate particles are the first mineralized structures to be formed in the calcification process in cardiovascular tissues. Furthermore, the inner sections of calcified lesions in patients with various cardiovascular diseases are identified as highly crystalline, spherical hydroxyapatite particles that differ in structure from bone mineral.
- Sergio Bertazzo
- , Eileen Gentleman
- & Molly M. Stevens