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Letter |
Molecular modifiers reveal a mechanism of pathological crystal growth inhibition
Like citrate, the molecule hydroxycitrate is shown to inhibit growth of the crystal that is the principal component of kidney stones, suggesting that hydroxycitrate could be another treatment for kidney stone disease.
- Jihae Chung
- , Ignacio Granja
- & Jeffrey D. Rimer
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Letter |
Nanoscale chemical tomography of buried organic–inorganic interfaces in the chiton tooth
Many biomineralized tissues (such as teeth and bone) are hybrid inorganic–organic materials whose properties are determined by their convoluted internal structures. Now, using a chiton tooth as an example, this study shows how the internal structural and chemical complexity of such biomaterials and their synthetic analogues can be elucidated using pulsed-laser atom-probe tomography.
- Lyle M. Gordon
- & Derk Joester