Adjuvants articles within Nature

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  • Article
    | Open Access

    FXR regulates the levels of ACE2 in tissues of the respiratory and gastrointestinal systems that are affected by COVID-19, and inhibiting FXR with ursodeoxycholic acid downregulates ACE2 and reduces susceptibility to SARS-CoV-2 infection.

    • Teresa Brevini
    • , Mailis Maes
    •  & Fotios Sampaziotis
  • Article |

    Trials in rhesus macaques show that a subunit vaccine against SARS-CoV-2, comprising the spike protein receptor-binding domain displayed on a nanoparticle protein scaffold, produces a robust protective response against the virus.

    • Prabhu S. Arunachalam
    • , Alexandra C. Walls
    •  & Bali Pulendran