The genetic and environmental risks combined confer the total risk for a complex phenotype
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The genetic and environmental risks combined confer the total risk for a complex phenotype
The genetic risk could be subdivided into that contributed by the SNP alleles, and that contributed by copy number variation (CNV alleles or copy number dosage). SNV, single nucleotide variant.
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Did you know that a large number of your genes exist in variable numbers of copies? While they can overlap with disease-related genes, these variants exist in healthy individuals too.
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