Inhaled nitric oxide prevented the hyperoxia induced decrease in murine alveolar number. In addition, reduced intercellular adhesion molecule (ICAM) and monocyte chemotactic protein-1 dependent recruitment of neutrophils and macrophages to the lung exists.
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A thirty minute hyperoxic exposure after acute hypoxia was sufficient to increase matrix metalloproteinase gelatinase activity in neonatal piglet livers.
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A broad spectrum matrix metalloproteinase and tumor necrosis factor-α-converting enzyme inhibitor reduced the ischemia-reperfusion injury induced acute tubular necrosis in mice.
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Artificially reared male rats demonstrate greater morphine-induced Fos-immunoreactivity in the mesocorticolimbic reward circuitry versus the maternally reared counterpart.
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Galactose restricted diet is life saving in neonates with classic galactosemia. Abnormal glycosylation of serum glycoproteins indicates persistence of metabolic dyshomeostasis and gene dysregulation in the treated individuals.
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Training in reducing stressful experiences for parents of preterm (<30 weeks gestation) infants demonstrated improved cerebral white matter microstructural development at term-equivalent (40 weeks postmenstrual age).
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Editor's Focus. Pediatr Res 67, A5 (2010). https://doi.org/10.1203/PDR.0b013e3181d49060
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DOI: https://doi.org/10.1203/PDR.0b013e3181d49060