TABLE OF CONTENTS

Volume 24, Issue 1 (6 January 2005)

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Review

Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells

Ralph Wäsch and Dirk Engelbert

Oncogene 24: 1-10; doi:10.1038/sj.onc.1208017

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Commentary

Poly(ADP-ribose): a co-regulator of DNA methylation?

Felix R Althaus

Oncogene 24: 11-12; doi:10.1038/sj.onc.1208382

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Original Papers

Modulation of DNMT1 activity by ADP-ribose polymers

Anna Reale, Giovanna De Matteis, Giada Galleazzi, Michele Zampieri and Paola Caiafa

Oncogene 24: 13-19; doi:10.1038/sj.onc.1208005

The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans

Florence Solari, Angélique Bourbon-Piffaut, Ingrid Masse, Bernard Payrastre, Andrew M -L Chan and Marc Billaud

Oncogene 24: 20-27; doi:10.1038/sj.onc.1207978

Characterization of VIK-1: a new Vav-interacting Kruppel-like protein

Martin Houlard, Francisco Romero-Portillo, Antonia Germani, Arnaud Depaux, Fabienne Regnier-Ricard, Sylvie Gisselbrecht and Nadine Varin-Blank

Oncogene 24: 28-38; advance online publication, November 22, 2004; doi:10.1038/sj.onc.1208043

Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice

Patricia M Alli, Michael L Pinn, Elizabeth M Jaffee, Jill M McFadden and Francis P Kuhajda

Oncogene 24: 39-46; advance online publication, October 18, 2004; doi:10.1038/sj.onc.1208174

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Papers

Functional identification of a BAC clone from 16q24 carrying a senescence gene SEN16 for breast cancer cells FREE

Gursurinder Pal Kaur, Deepthi E Reddy, Drazen B Zimonjic, Jon K de Riel and Raghbir S Athwal

Oncogene 24: 47-54; advance online publication, November 22, 2004; doi:10.1038/sj.onc.1208175

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Original Papers

Blockage of CRM1-dependent nuclear export of the adenovirus type 5 early region 1B 55-kDa protein augments oncogenic transformation of primary rat cells

Christian Endter, Barbara Härtl, Thilo Spruss, Joachim Hauber and Thomas Dobner

Oncogene 24: 55-64; advance online publication, October 11, 2004; doi:10.1038/sj.onc.1208170

Cytoskeletal modification of Rho guanine nucleotide exchange factor activity: identification of a Rho guanine nucleotide exchange factor as a binding partner for Sept9b, a mammalian septin

Koh-Ichi Nagata and Masaki Inagaki

Oncogene 24: 65-76; advance online publication, November 22, 2004; doi:10.1038/sj.onc.1208101

Manganese superoxide dismutase overexpression inhibits the growth of androgen-independent prostate cancer cells

Sujatha Venkataraman, Xiaohong Jiang, Christine Weydert, Yuping Zhang, Hannah J Zhang, Prabhat C Goswami, Justine M Ritchie, Larry W Oberley and Garry R Buettner

Oncogene 24: 77-89; advance online publication, November 15, 2004; doi:10.1038/sj.onc.1208145

Signaling properties and expression in normal and tumor tissues of two phospholipase C epsilon splice variants

Sonia Caroline Sorli, Tom D Bunney, Peter H Sugden, Hugh F Paterson and Matilda Katan

Oncogene 24: 90-100; advance online publication, November 22, 2004; doi:10.1038/sj.onc.1208168

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Papers

Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor

Yu-Wen Zhang, Yanli Su, Nathan Lanning, Margaret Gustafson, Nariyoshi Shinomiya, Ping Zhao, Brian Cao, Galia Tsarfaty, Ling-Mei Wang, Rick Hay and George F Vande Woude

Oncogene 24: 101-106; advance online publication, November 8, 2004; doi:10.1038/sj.onc.1208181

Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction

Lihua Du, Christopher S Lyle and Timothy C Chambers

Oncogene 24: 107-117; advance online publication, November 8, 2004; doi:10.1038/sj.onc.1208189

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Original Papers

Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma

Angela M Jones, Eleanor J Douglas, Sarah ER Halford, Heike Fiegler, Patricia A Gorman, Rebecca R Roylance, Nigel P Carter and Ian P M Tomlinson

Oncogene 24: 118-129; advance online publication, November 8, 2004; doi:10.1038/sj.onc.1208194

Type I and type II reactions in TRAIL-induced apoptosis − results from dose−response studies

Justine Rudner, Verena Jendrossek, Kirsten Lauber, Peter T Daniel, Sebastian Wesselborg and Claus Belka

Oncogene 24: 130-140; advance online publication, November 8, 2004; doi:10.1038/sj.onc.1208191

Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas

Young Hwa Soung, Jong Woo Lee, Su Young Kim, Yong Jik Sung, Won Sang Park, Suk Woo Nam, Sang Ho Kim, Jung Young Lee, Nam Jin Yoo and Sug Hyung Lee

Oncogene 24: 141-147; advance online publication, November 8, 2004; doi:10.1038/sj.onc.1208244

The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein

Mandar R Bhonde, Marie-Luise Hanski, Roberta Magrini, Dhatchana Moorthy, Antje Müller, Edward A Sausville, Kimitoshi Kohno, Peter Wiegand, Peter T Daniel, Martin Zeitz and Christoph Hanski

Oncogene 24: 148-156; advance online publication, September 27, 2004; doi:10.1038/sj.onc.1207842

Loss of heterozygosity and histone hypoacetylation of the PINX1 gene are associated with reduced expression in gastric carcinoma

Tomohiro Kondo, Naohide Oue, Yoshitsugu Mitani, Hiroki Kuniyasu, Tsuyoshi Noguchi, Kazuya Kuraoka, Hirofumi Nakayama and Wataru Yasui

Oncogene 24: 157-164; doi:10.1038/sj.onc.1207832

Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas

Johannes H Schulte, Alexander Schramm, Ludger Klein-Hitpass, Michael Klenk, Hendrika Wessels, Berthold P Hauffa, Jürgen Eils, Roland Eils, Garrett M Brodeur, Lothar Schweigerer, Werner Havers and Angelika Eggert

Oncogene 24: 165-177; advance online publication, November 8, 2004; doi:10.1038/sj.onc.1208000

Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression

Meryem Bektas, Puneet S Jolly, Carola Müller, Jürgen Eberle, Sarah Spiegel and Christoph C Geilen

Oncogene 24: 178-187; doi:10.1038/sj.onc.1208019

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Oncogenomics

Loss of HOXC6 expression induces apoptosis in prostate cancer cells

Sumathi Ramachandran, Pengbo Liu, Andrew N Young, Qiqin Yin-Goen, So Dug Lim, Noelani Laycock, Mahul B Amin, Jeffrey K Carney, Fray F Marshall, John A Petros and Carlos S Moreno

Oncogene 24: 188-198; doi:10.1038/sj.onc.1207906

Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway

Edoardo Missiaglia, Massimo Donadelli, Marta Palmieri, Tatjana Crnogorac-Jurcevic, Aldo Scarpa and Nicholas R Lemoine

Oncogene 24: 199-211; doi:10.1038/sj.onc.1208018

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