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Nature Structural & Molecular Biology 15, 899–900 (1 September 2008) | doi:10.1038/nsmb0908-899
Sister chromatids caught in the cohesin trap
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Abstract
During cell division, the two sister chromatids are held together by the cohesin complex until the onset of anaphase, when a protease called separase opens the cohesin rings. This releases cohesin from the chromosomes and allows segregation of sister chromatids to opposite poles.
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