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Nature Structural & Molecular Biology 15, 897–898 (1 September 2008) | doi:10.1038/nsmb0908-897

A new, leaner and meaner bacterial organelle

Sabine Heinhorst & Gordon C Cannon

Contrary to the long-held belief that prokaryotic cells are essentially unstructured sacks of cytoplasm and that compartmentalization is a prerogative of eukaryotes, recent studies using EM, structural and biochemical approaches have shifted this paradigm. The advances in the field are documented in two recent monographs entirely devoted to the multitude of intracellular structures found in prokaryotes, ranging from simple storage granules and cytoskeletal elements to more elaborate structures with key functions in metabolism.