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Nature Structural & Molecular Biology 15, 893–895 (1 September 2008) | doi:10.1038/nsmb0908-893
Insights into PPAR|[gamma]| from structures with endogenous and covalently bound ligands
Abstract
PPARγ is a member of the nuclear receptor superfamily of transcription factors. PPARγ was found to be the receptor for the class of antidiabetic drugs known as thiazolidinediones (TZDs), such as rosiglitazone, which promote insulin sensitization but also induce adipogenesis.
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