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Energizing type III secretion machines: what is the fuel?

Bacterial type III secretion machines have adapted to carry out numerous functions, ranging from locomotion to protein delivery into nucleated cells. One of the most intriguing issues is the source of energy that fuels their activities. Despite recent advances, there are still many questions to be resolved.

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Figure 1: Model for the energizing of type III secretion machines.

Kim Caesar

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Acknowledgements

I would like to thank J. Kato and M. Lara-Tejero for useful suggestions and critical reading of this manuscript. Work in the Galán laboratory is supported by grants from the US National Institutes of Health.

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Galán, J. Energizing type III secretion machines: what is the fuel?. Nat Struct Mol Biol 15, 127–128 (2008). https://doi.org/10.1038/nsmb0208-127

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