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Nature Structural & Molecular Biology 15, 1128–1130 (1 November 2008) | doi:10.1038/nsmb1108-1128
A major switch for the Fanconi anemia DNA damage|[ndash]|response pathway
Abstract
Fanconi anemia is a rare genetic disease characterized by genomic instability, cancer predisposition, bone marrow failure and various developmental abnormalities. Increasing excitement has been generated from studies of this disease, as three Fanconi anemia genes, FANCD1, FANCN and FANCJ, have been found to be identical to breast cancer susceptibility (BRCA) genes BRCA2, PALB2 and BACH1, respectively.
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