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A sorting importin on Sec61

Nature Structural & Molecular Biology volume 13, pages 476–478 (2006)Cite this article

A recent report identifies a cellular protein that recognizes inner nuclear membrane (INM) targeting signals. This finding provides the missing link for the transport of large inner nuclear membrane proteins as they travel from the cytosolic face of the endoplasmic reticulum to the INM.

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Figure 1: The domain structure of importin-α and importin-α-16.
Figure 2: The route of transport for inner nuclear membrane proteins from the ER to the INM.

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  1. 250 Sinsheimer Laboratories, University of California, Santa Cruz, 95064, California, USA

    Michael F Rexach

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  1. Michael F Rexach
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Rexach, M. A sorting importin on Sec61. Nat Struct Mol Biol 13, 476–478 (2006). https://doi.org/10.1038/nsmb0606-476

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