Collection of articles from the Nature Research journals covering advances in understanding the gut-brain axis.

In this collection, the cancer editorial community of the Nature journals presents the most recently published articles on cancer evolution. The topic is discussed from different angles (preclinical, translational and clinical), and across a range of tumour types.

The past 10 years has seen great advances in the understanding and treatment of human disease. For expert perspectives on the most important breakthroughs, don't miss the FREE A Decade in Medicine eBook. In this special collection of 47 articles, leading experts highlight the most important advances in eight medical specialties between 2004 and 2015, and comment on future developments in their fields.

Nature Reviews Urologyis proud to present the Men's Health Collection in partnership with the Movember Foundation. The issue of men's health has increased in the public awareness in recent years and emerged as a new discipline that is responsible for a gender-specific approach to health-services delivery, government policy, research, and advocacy. An improved focus on men's health is needed as the average life expectancy for men is lower than for women in almost all countries and social influences mean that, often, men do not see their health as a priority. Charities have had a major role in promoting men's health as an issue for society in general, as well as providing support and funding for research. This special collection of articles by key opinion leaders highlights issues that are important to men, their families, and their physicians, and provides a resource for these interested parties in the areas of prostate cancer, BPH, fertility, and testosterone deficiency. The male-health paradigm and the influence of charities in championing this important cause are also discussed. All content has been chosen by the editors ofNature Reviews Urology.

November 2014 marks the 10th anniversary of the launch of Nature Reviews Urology, originally published under the title ofNature Clinical Practice Urology. To celebrate this milestone, we present a special Anniversary issue. These specially commissioned articles written by members of our international Advisory Board, together with a special infographic, summarize the major advances in Urology over the past 10 years alongside predictions for the future of the field.

In the developed world, birth rates are plummeting and, increasingly, individuals are delaying reproduction. At the same time, rising rates of obesity and cancer are affecting fertility (both by virtue of the disease burden and the effects of treatment). A number of factors have been shown to affect fertility in men and women, including oxidative stress, hormonal and metabolic dysfunction and physical deformity. This joint Nature Reviews UrologyandNature Reviews Endocrinologycollection on fertility and reproduction contains Reviews and commentaries written by key opinion leaders on a range of topics pertinent to the subject, from the molecular mechanisms regulating fertility and reproduction to the preservation of fertility and treatment of infertility in both men and women.

The field of paediatric urology has evolved in recent years, with an increased focus on minimally invasive treatment, evidence-based interventions, and guideline adherence. This Focus issue from Nature Reviews Urologyfeatures a series of specially commissioned Review and News & Views articles written by key opinion leaders in the field of paediatric urology. Topics covered include the use of robotic urological surgery in children, the role of bladder and bowel dysfunction in children with vesicoureteral reflux, urinary incontinence in children with special needs, grading systems and management of mild to moderate postnatal hydronephrosis, and the treatment of failed hypospadias.

This specially commissioned Focus contains articles from key opinion leaders on the contemporary challenges faced by clinicians treating patients with a small renal mass, from the importance of preserving renal tissue and the controversial use of active surveillance to the promise of new focal therapies and robotic partial nephrectomy.

Sexual Medicine represents a dynamic and varied field, covering a wide range of clinical specialties. This special Focus issue of Nature Reviews Urologycontains specially commissioned articles that present the most exciting research in the sexual medicine spectrum. Reviews cover the topics of regenerative medicine, the neurobiology of the sexual response, the hormonal control of ejaculation and management strategies for micropenis. We also include a Perspectives discussing the challenges facing the field and a number of News & Views articles discussing recent research in sexual medicine.

This Focus contains a dozen specially-commissioned articles on state-of-the-art diagnosis, management and monitoring of patients with kidney cancer in the era of 'targeted therapies'.