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Stroke has been misplaced in the International Classification of Disease (ICD) since 1955, but is now classed as a neurological disease in the new ICD-11. The reclassification required a bureaucratic struggle between clinicians and the World Health Organization, but will bring great benefits.
The treatment of multiple sclerosis (MS) has evolved remarkably over the past 25 years. This progress has been enabled by advances in research, drug development and active engagement of the scientific community with regulatory authorities. However, an inconsistent approach to MS disease courses could have a negative impact on the drug development process.