Figures and Tables

From the following article:

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

Nicholas P. Franks

Nature Reviews Neuroscience 9, 370-386 (May 2008)

doi:10.1038/nrn2372

Figure 1 - General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

Figure 1

Loss of consciousness in humans occurs over a very narrow range of anaesthetic concentrations and correlates with loss of the righting reflex in rodents.

Figure 2 - General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

Figure 2

Three key molecular targets and some known determinants of their anaesthetic sensitivities.

Figure 3 - General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

Figure 3

Functional brain imaging reveals similarities between anaesthetic-induced loss of consciousness and deep natural sleep.