Table of contents

December 2008 Vol 9 No 12

Also this month:


From the editors

p885 | doi:10.1038/nrn2550

Top

Research Highlights

Synapse formation: The missing link | PDF (200 KB)

p886 | doi:10.1038/nrn2549

Brain–machine interfaces: Back in control | PDF (142 KB)

p887 | doi:10.1038/nrn2534

Neurodegenerative disease: Giving survival a boost | PDF (126 KB)

p887 | doi:10.1038/nrn2542

Mirror neurons: Towards a clearer image | PDF (158 KB)

p888 | doi:10.1038/nrn2544

Neurogenesis: Seeking stem cells | PDF (138 KB)

p888 | doi:10.1038/nrn2546

In the news

Rain man? | PDF (116 KB)

p888 | doi:10.1038/nrn2553

In brief

Glia | Memory | Learning and memory | Circadian rhythms | PDF (138 KB)

p889 | doi:10.1038/nrn2552

Neuropeptides: Vasopressin: not just for males | PDF (149 KB)

p890 | doi:10.1038/nrn2543

Ion channels: Small conductance, big effects | PDF (140 KB)

p890 | doi:10.1038/nrn2547

Behaviour: Doing the locomotion | PDF (127 KB)

p891 | doi:10.1038/nrn2541

Development: It's all in the timing | PDF (214 KB)

p892 | doi:10.1038/nrn2545

An Interview With...

The Kavli prize winners | PDF (251 KB)

p893 | doi:10.1038/nrn2548

Top

Reviews

VPS10P-domain receptors — regulators of neuronal viability and function

Thomas E. Willnow, Claus M. Petersen & Anders Nykjaer

p899 | doi:10.1038/nrn2516

Recent work has shown that VPS10P-domain receptors have important roles in neuronal signalling pathways. Willnow and colleagues outline the evidence for the contributions of two of these proteins, sortilin and SORLA, to neuronal viability and function.

Article series: Sleep

Sleep as a fundamental property of neuronal assemblies

James M. Krueger, David M. Rector, Sandip Roy, Hans P. A. Van Dongen, Gregory Belenky & Jaak Panksepp

p910 | doi:10.1038/nrn2521

Sleep has long been viewed as a property of the whole animal that is regulated by sleep- and wake-promoting neuronal networks. Here, Krueger and colleagues review the evidence that sleep might instead be regulated locally, at the level of neuronal assemblies.

A cortical network for semantics: (de)constructing the N400

Ellen F. Lau, Colin Phillips & David Poeppel

p920 | doi:10.1038/nrn2532

Event-related potentials (ERPs) have been widely used to investigate language processing in the brain. Lau and colleagues discuss how localization data can contribute to the functional interpretation of one particular component of the ERP — the N400 response.

Human volition: towards a neuroscience of will

Patrick Haggard

p934 | doi:10.1038/nrn2497

Recent studies have identified networks of brain areas that underlie voluntary action. Patrick Haggard reviews these circuits, describes the types of decision that are involved in making a voluntary action and discusses how volition is linked to conscious experience.

Top

Perspectives

Opinion

Why do many psychiatric disorders emerge during adolescence?

Tomás caron Paus, Matcheri Keshavan & Jay N. Giedd

p947 | doi:10.1038/nrn2513

Many psychiatric disorders emerge in adolescence, when profound changes take place in the brain. Paus and colleagues provide an overview of the neurobiological changes that occur during adolescence and discuss their possible relationship to the emergence of psychopathology.

Science and society

Beyond polemics: science and ethics of ADHD

Ilina Singh

p957 | doi:10.1038/nrn2514

The rates of ADHD diagnosis have increased sharply in most countries around the world. This Perspective examines the current state of scientific research into ADHD and the key social and ethical concerns that are emerging from the use of stimulant drug treatments in children.

See also: Erratum associated with this article

Correspondence

Correspondence: Paying attention to reading direction

Seta Kazandjian & Sylvie Chokron

p965 | doi:10.1038/nrn2456-c1

Author Reply: Reading direction and culture

Shihui Han & Georg Northoff

p965 | doi:10.1038/nrn2456-c2

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