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This study reports that Vibrio cholerae outer membrane vesicles protect the cholera toxin from degradative enzymes in the intestinal tract and deliver the active toxin to host cells by a porin-mediated mechanism.
This study finds that a deadly skin disease in red squirrels is associated with a staphylococcal clone often acquired through spillover from other hosts.
A recent study reports the discovery of bat coronaviruses that are closely related to SARS-CoV-2, including a virus that displays high sequence identity to SARS-CoV-2 in most genomic regions.
This study reports the evolution of a bacterial enzyme that does not have an inherent RNA-binding activity into a virus-like nucleocapsid protein that efficiently packages and encapsidates copies of its own mRNA.
This month’s Under the Lens discusses the application of the quantitative image analysis software BiofilmQ to understand antibiotic-induced changes in Vibrio cholerae biofilms at single-cell resolution.
In this Review, Steensels, Gallone and Verstrepen discuss the origin and evolution of fungal interspecific hybrids and provide examples of how hybridization produced useful hybrids for industrial fermentations but also resulted in the emergence of highly virulent pathogens.
In this Review, Correa and colleagues revisit the rules of life for viruses of microorganisms by advancing a conceptual framework that recognizes virus–host interactions across a continuum of infection modalities and by examining the influence of these modalities on viruses, their hosts and ecosystems.
The human body hosts vast numbers of different viruses, collectively termed the virome. In this Review, Liang and Bushman provide an overview of research on the human virome and highlight recent studies that explore the assembly and composition of the human virome as well as host–virome interactions in health and disease.
In this Review, Leung provides an overview of the transmissibility and modes of transmission of respiratory viruses, the viral, host and environmental determinants of transmission, and common non-pharmaceutical interventions for mitigating respiratory virus transmission. She also discusses the recent controversies over aerosol transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.
