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Two new studies explore the effect of overexpression of efflux pumps on bacterial fitness as well as the effect of loss of efflux function on virulence.
Two independent recent studies have revealed how distinct components of the biofilm matrix contribute to its architectural stability and functionality.
Two recent studies shed light on the mechanisms that coordinate cell division with chromosomal replication and segregation in two distinct bacterial species.
This month's Genome Watch discusses how genome-wide epistasis analysis and genome-to-genome analyses are providing insights into the relevance of interactions between and within genomes of pathogens and their hosts.
Species in the genusPseudomonas thrive in diverse ecological niches and are infected with equally diverse bacteriophages. In this Review, De Smet et al. discuss the interactions between Pseudomonasspp. and their phages and also address the biotechnological applications that may be derived from phage–bacteria interactions.
The transmission of commensal intestinal bacteria between humans could promote health by establishing, maintaining and replenishing microbial diversity in the microbiota of an individual. In this Review, Browne and colleagues discuss the mechanisms and factors that influence host-to-host transmission of the intestinal microbiota.
In this Review, Pedra and colleagues describe the advances and challenges in the genetic engineering of obligate intracellular bacteria, and highlight examples of how the use of genetically manipulated pathogens has improved our understanding of microbial pathogenesis and host–pathogen interactions.
The release of membrane-bound vesicles from cells is being increasingly recognized as a mechanism of intercellular communication. In this Review, Raab-Traub and Dittmer discuss the roles that extracellular vesicles have during virus infection.
