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This study reveals that ribosomal antibiotics function in a context-specific manner, dependent on the penultimate amino acid in the nascent chain and the amino acid in the P-site of the peptidyl transferase center.
This study shows that the bacterial effector Sca4 promotes intercellular spread of the obligate intracellular pathogenRickettsia parkeriby disrupting the transmission of intercellular tension at cell–cell adherence junctions.
This month's Genome Watch describes how Mash can be used to tackle comparisons between large amounts of genomic and metagenomic sequence data for taxonomic applications.
Why have multi-partner endosymbioses evolved on several independent occasions in plant sap-feeding insects? In this Review, Douglas discusses the composition and functions of these endosymbioses, and considers the processes and adaptive forces that drive their evolution.
Treponema pallidum, the causative agent of syphilis, is extremely well adapted to its host. In this Review, Radolf and colleagues discuss how this pathogen has streamlined its cell envelope, metabolism and genome to thrive and cause disease in humans.
Fungal genomics studies have shown that ectomycorrhizal fungi have arisen in approximately 60 independent saprotrophic lineages. In this Review, Martin and colleagues describe the functional gains and losses that have occurred during the evolution of ectomycorrhizal symbioses.
Similarly to competing endogenous RNAs (ceRNAs) in mammalian cells, competition for regulatory RNAs and proteins can lead to crosstalk between bacterial mRNAs. In this Opinion article, Bossi and Figueroa-Bossi argue that such competition for regulatory targets may have a substantial influence on bacterial gene networks.
