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Faecal microbiota transplant (FMT) is now accepted as an effective treatment for Clostridioides difficile infections. With the increasing number of FMT treatments and clinical trials for other indications there is an urgent need for standardized regulations to ensure patient safety and focused development of safer, rationally designed, microbiota-based medicines.
Global change microbiology is a rapidly growing research field on microbial responses to global warming, overuse and pollution and on feedback mechanisms and functions that affect Earth’s element cycles and planetary health. In this Comment, Antje Boetius explores how this field could provide essential knowledge and sustainable solutions to the problems driven by global change.
The recent large outbreak of Ebola virus disease (EVD) in Western Africa resulted in greatly increased accumulation of human genotypic, phenotypic and clinical data, and improved our understanding of the spectrum of clinical manifestations. As a result, the WHO disease classification of EVD underwent major revision.
