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Nature Reviews Gastroenterology and Hepatology 6, 131 (1 March 2009) | doi:10.1038/ncpgasthep1349

Administration of physiologic plasma lipid reduces food intake in rats and mice

Gillum MP et al. (2008) N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake. Cell 135: 813–824 Regulation of the intake of dietary fat, the macronutrient that most promotes obesity, is a primary target of research into obesity.