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The use of CT has been increasing exponentially over the past decade. Unfortunately, there is little cognizance among health-care providers (or their patients) about the relative latent cancer risks associated with repetitive exposure to ionizing radiation. Given the exposure of a relatively high proportion of the population to these tests, it is incumbent on health-care providers to have an improved understanding of these risks and discuss them accordingly with their patients.
The incidence ofClostridium difficile infection has dramatically risen, in concert with the increasing use of PPIs for gastric acid suppression. This Perspective focuses on the role that PPI use may have in C. difficileinfection, and weighs up the pros and cons of PPI therapy.
