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Pituitary tumors

Cabergoline versus bromocriptine: a meta-analysis?

A systematic review and meta-analysis by Dos Santos Nunes et al. has compared the benefits and risks of cabergoline versus bromocriptine for the treatment of patients with hyperprolactinemia. This analysis confirms previous reports that cabergoline is more efficacious and better tolerated than bromocriptine.

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References

  1. Dos Santos Nunes, V., El Dib, R., Boguszewski, C. L. & Nogueira, C. R. Cabergoline versus bromocriptine in the treatment of hyperprolactinemia: a systematic review of randomized controlled trials and meta-analysis. Pituitary doi:10.1007/s11102-010-0290-z.

  2. Gillam, M. P., Molitch, M. E., Lombardi, G. & Colao, A. Advances in the treatment of prolactinomas. Endocr. Rev. 27, 485–534 (2006).

    Article  CAS  Google Scholar 

  3. Colao, A. et al. Prolactinomas resistant to standard dopamine agonists respond to chronic cabergoline treatment. J. Clin. Endocrinol. Metab. 82, 876–883 (1997).

    Article  CAS  Google Scholar 

  4. Iyer, P. & Molitch, M. E. Positive prolactin response to bromocriptine in two patients with cabergoline resistant prolactinomas. Endocr. Pract. doi:10.4158/EP10369.CR

  5. Ono, M. et al. Prospective study of high-dose cabergoline treatment of prolactinomas in 150 patients. J. Clin. Endocrinol. Metab. 93, 4721–4727 (2008).

    Article  CAS  Google Scholar 

  6. Molitch, M. E. The cabergoline-resistant prolactinoma patient: new challenges. J. Clin. Endocrinol. Metab. 93, 4643–4645 (2008).

    Article  CAS  Google Scholar 

  7. Dekkers, O. M. et al. Recurrence of hyperprolactinemia after withdrawal of dopamine agonists: systematic review and meta-analysis. J. Clin. Endocrinol. Metab. 95, 43–51 (2010).

    Article  CAS  Google Scholar 

  8. Molitch, M. E. Prolactinomas and pregnancy. Clin. Endocrinol. (Oxf.) 73, 147–148 (2010).

    Google Scholar 

  9. Smith, G. C. & Pell, J. P. Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomized controlled trials. BMJ 327, 1459–1461 (2003).

    Article  Google Scholar 

  10. Lewiecki, E. M. & Binkley, N. Evidence-based medicine, clinical practice guidelines, and common sense in the management of osteoporosis. Endocr. Pract. 15, 573–579 (2009).

    Article  Google Scholar 

Download references

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Molitch, M. Cabergoline versus bromocriptine: a meta-analysis?. Nat Rev Endocrinol 7, 254–255 (2011). https://doi.org/10.1038/nrendo.2011.33

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