Review

Nature Reviews Drug Discovery 3, 673-683 (August 2004) | doi:10.1038/nrd1468

Drug repositioning: identifying and developing new uses for existing drugs

Ted T. Ashburn1 & Karl B. Thor1  About the authors

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Biopharmaceutical companies attempting to increase productivity through novel discovery technologies have fallen short of achieving the desired results. Repositioning existing drugs for new indications could deliver the productivity increases that the industry needs while shifting the locus of production to biotechnology companies. More and more companies are scanning the existing pharmacopoeia for repositioning candidates, and the number of repositioning success stories is increasing.

Author affiliations

  1. Dynogen Pharmaceuticals, Inc., 31 St James Avenue, Suite 905, Boston, Massachusetts 02116, USA.

Correspondence to: Ted T. Ashburn1 Email: tashburn@dynogen.com

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