Table of contents
February 2004 Vol 3 No 2
In this issue
p99 | doi:10.1038/nrd1321
Editorial: Colonizing therapeutic space: the overlooked science of drug husbandry
p101 | doi:10.1038/nrd1315
News and Analysis
News
2003 approvals: a year of innovation and upward trends
p103 | doi:10.1038/nrd1327
News
Patent watch
Apotex loses case based on the 'Festo' ruling
p106 | doi:10.1038/nrd1314
Patent watch
Purdue appeals OxyContin patents
p106 | doi:10.1038/nrd1316
Patent watch
Patent write-offs are a write off
p106 | doi:10.1038/nrd1320
From the analyst's couch
The licensing gamble: raising the stakes
p107 | doi:10.1038/nrd1310
Fresh from the Pipeline
Memantine hydrochloride
p109 | doi:10.1038/nrd1311
Research Highlights
Anticancer drugs: Unleashing p53
p111 | doi:10.1038/nrd1313
Drug delivery: Breaking the skin barrier
p112 | doi:10.1038/nrd1312
Bone disease: Shedding light on a silent pathway
p112 | doi:10.1038/nrd1322
Sepsis: New forms of attack
p113 | doi:10.1038/nrd1324
Respiratory diseases: Hitting the MARCKS
p114 | doi:10.1038/nrd1317
In brief
Neurodegenerative Disease | Structural Genomics | Cardiovascular Disease | Regenerative Medicine
p114 | doi:10.1038/nrd1318
Reviews
Current status and future potential of transdermal drug delivery
Mark R. Prausnitz, Samir Mitragotri & Robert Langer
p115 | doi:10.1038/nrd1304
cAMP detection methods in HTS: selecting the best from the rest
Christine Williams
p125 | doi:10.1038/nrd1306
From monoamines to genomic targets: a paradigm shift for drug discovery in depression
Ma-Li Wong & Julio Licinio
p136 | doi:10.1038/nrd1303
Oxygen therapeutics: can we tame haemoglobin?
Abdu I. Alayash
p152 | doi:10.1038/nrd1307
Cytokine–receptor pairing: accelerating discovery of cytokine function
Don Foster, Julia Parrish-Novak, Brian Fox & Wenfeng Xu
p160 | doi:10.1038/nrd1305
Perspectives
Science and society
Engaging biotechnology companies in the development of innovative solutions for diseases of poverty
Hannah E. Kettler & Sonja Marjanovic
p171 | doi:10.1038/nrd1308
Opinion
Biotechnology: identifying advances from the hype
Robert H. Glassman & Anthony Y. Sun
p177 | doi:10.1038/nrd1309


