Keyword Index

[¹¹C]-(+)-PHNO…………………………S384, S402

17β-estradiol…………………………S199, S200

2-AG…………………………S295, S442

5-HT…………………………S19, S51, S59, S60, S62, S76, S77, S85–S86, S129, S136, S183, S184, S210, S224, S225, S265, S282, S297, S304, S307, S310, S329, S429, S430, S433, S437

5-HT1B…………………………S79, S224, S225, S331

5-HT7…………………………S224, S225, S430–S436

5-HTP…………………………S77, S206, S297

5-HT2A receptor…………………………S181, S282, S335

5HT2C receptor…………………………S306

5-HTP…………………………S77, S206, S297

A-85380…………………………S179, S402

A2…………………………S111

A

Abeta…………………………S44, S91

Abstinence…………………………S50, S165, S178, S179, S190, S192, S235, S236, S243, S282, S285, S291, S311, S328, S331, S368, S378, S380, S402, S404, S427

Abuse…………………………S6, S14, S19, S35, S47–S50, S81, S87, S118, S127, S145, S148, S149, S159, S167, S179, S189, S190, S195, S196, S216, S217, S230, S243, S262, S263, S284, S285, S289, S291, S301, S316, S322, S326, S330, S342, S365, S367, S369–S372, S375, S377, S379, S397, S404, S426, S440, S441

Abuse potential…………………………S192, S217, S429

Acamprosate…………………………S114, S381, S382

ACC…………………………S27, S28, S36, S53, S110, S112, S114, S118, S119, S125, S134, S135, S140, S141, S156, S157, S163, S165, S221, S238, S269, S272, S276, S285, S286, S312, S314, S321, S345, S361, S381, S382, S386, S387, S388–S391

Accumbens…………………………S50, S72, S145, S164, S165, S183, S265, S333, S393

Accumbens shell…………………………S334

ACE inhibitor…………………………S179

Acetylcholine receptors…………………………S96, S179, S180, S184, S326, S367, S372, S373, S379, S402

Acetyl-L-carnitine…………………………S345

Acoustic startle…………………………S54, S77, S78, S133, S183, S240, S242, S448

ACTH…………………………S324, S378

Actin…………………………S255, S260, S336, S339

Acute…………………………S1, S4, S5, S7, S14, S16–S18, S20, S24, S38, S44, S49, S56, S60, S67, S81, S82, S84, S88, S95, S96, S98, S101, S125–S127, S136, S146, S158, S168, S170, S172, S176–S178, S182, S188, S191, S192, S195, S196, S203–S205, S208, S212, S215, S216, S222, S229, S236, S238, S262, S268, S276, S278, S285, S287, S289, S295, S305, S306, S311, S312, S314, S317, S320, S322, S325, S329, S331, S332, S338, S341, S343, S346–S349, S352, S354, S359, S366, S367, S372, S377, S378, S381, S383, S395, S403–S405, S410, S411, S427, S430, S436, S445–S447

Acute exacerbation of schizophrenia…………………………S98, S106

Acute trauma…………………………S268

Addiction…………………………S1, S6, S7, S9, S11, S13, S14, S17, S19, S21, S28, S35, S47, S50, S78, S81, S132, S164, S166, S175, S189–S193, S196, S197, S211, S216, S235, S239, S261, S265, S277, S280, S283, S286, S288, S289, S301, S308, S311, S319–S321, S323–S327, S329, S331–S334, S336, S338, S342, S367, S372–S380, S384, S396, S402–S405, S428, S431, S439–S441, S446

Addiction liability…………………………S311

Adenosine…………………………S322, S338, S375

Adenylyl cyclase…………………………S311, S333

ADHD…………………………S5, S10, S36, S55, S66, S69, S80, S84, S112, S126, S136, S149–S156, S163, S187, S199, S230, S237, S238, S249, S250, S252, S255, S260, S265, S290, S310, S398, S420, S446, S448

Adherence…………………………S65, S105, S167, S305, S422

Adjunctive treatment…………………………S100, S108, S303, S346, S356, S359, S416

Adolescence…………………………S5, S6, S11, S18, S21, S32, S49, S50, S60, S68, S83, S111, S136, S141, S145, S147, S148, S214, S215, S238, S240, S256, S273, S275, S283, S312, S316, S333, S336, S367, S377, S380, S389, S406, S409, S431, S442

Adolescent…………………………S5, S11, S15, S18, S21, S32, S50, S51, S69, S76, S77, S83, S84, S101, S135, S137, S145, S151, S160, S238, S243, S258, S273, S274, S296, S297, S307, S313, S316, S326, S342, S348, S366, S367, S370, S389, S390, S394, S398, S419, S431, S448

Adolescent depression…………………………S389, S390, S412

Adolescent-onset…………………………S275, S367, S390

Adrenergic beta-2 receptors…………………………S124, S125

Adult neurogenesis…………………………S89

Advanced paternal age…………………………S102, S250

Adverse effects…………………………S65, S101, S120, S169, S170, S175, S228, S229, S231, S235, S273, S299, S359, S418, S421

Affect regulation…………………………S109, S289

Affective disorders…………………………S7, S18, S56, S77, S85, S113, S126, S129, S144, S161, S172, S221, S252, S264, S368, S399, S410, S442, S448

Affective symptoms…………………………S69, S294, S331, S409

African American…………………………S97, S105, S305, S406, S424

Afro-trinidadians…………………………S177

Age…………………………S1, S3–S6, S10, S20, S23, S26, S27, S32, S34, S42, S43, S47, S49, S50, S52, S58, S63, S67–S71, S84, S87, S89, S92, S93, S96, S97, S102, S105, S106, S109, S112, S117, S120, S123–S130, S135, S138, S140, S141, S145–S149, S152–S156, S158–S161, S163, S164, S166–S169, S171, S172, S174, S176, S177, S180, S196, S200, S213, S219–S221, S224, S226–S229, S232, S236, S238–S241, S243, S244, S246, S249–S253, S255–S257, S259, S261, S262, S264–S268, S271, S272, S275–S280, S282, S285, S288, S290, S292, S296, S298, S301, S302, S306, S307, S313–S315, S318, S326, S327, S336, S337, S347–S349, S355, S357, S362, S366, S367, S369, S371, S377, S381–S386, S388–S392, S394–S403, S407–S411, S413, S419, S422, S423, S426, S439, S448

Aggression…………………………S60, S78, S81, S82, S120, S136, S136, S139, S152, S153, S160, S223, S227, S228, S262, S324, S345, S375, S392

Aging…………………………S3, S4, S26, S43, S63, S75, S92, S236, S254, S255, S275, S335, S398

Agitation…………………………S227, S419, S441

Agonist…………………………S3, S14, S19, S34, S36, S47, S50, S54, S55, S72, S76, S79, S97, S99, S106, S107, S126, S133, S169, S171, S178, S181–S184, S190, S192, S193, S195, S211, S214, S224, S225, S228, S237, S268, S286, S304, S307–S310, S312, S328, S331, S333, S340, S342, S375, S402, S428, S432, S437–S439, S441, S442

Akt…………………………S9, S21, S56, S90, S202, S203

AKT1…………………………S22, S49, S320

Alcohol…………………………S5, S7, S12, S52, S79–S81, S99, S105, S114, S143, S151, S164, S166, S177, S178, S181, S188, S191–S196, S259, S283–S291, S295, S301, S306, S322, S323, S325, S326, S329, S338, S341, S366, S368, S369, S371–S374, S378–S382, S404, S405, S423, S428–S430, S439

Alcohol abuse…………………………S52, S65, S154, S193, S324, S326, S341, S365, S372, S422, S428

Alcohol addiction…………………………S166

Alcohol challenge…………………………S177

Alcohol dependence…………………………S7, S12, S52, S114, S193, S195, S235, S285, S288, S301, S329, S371, S372, S374, S425, S428

Alcohol drinking…………………………S79, S80, S164, S180, S191, S194, S428

Alcohol withdrawal…………………………S7, S285

Alcoholic rats…………………………S164

Alcoholism…………………………S12, S79, S154, S164, S166, S177, S180, S191, S192, S283, S288, S301, S324, S326, S329, S338, S341, S342, S369, S372, S377, S403, S428, S429

Algorithm…………………………S65, S159, S268, S352, S381, S393, S398, S417, S428

Allopregnanolone…………………………S81, S340

Allosteric…………………………S59, S181, S181, S186, S227, S236, S310, S382, S437, S438

Allosteric modulator…………………………S230, S310, S382, S437, S438

Allosteric regulation…………………………S181

Alpha 3 subunit…………………………S372

Alpha 7 receptor agonist…………………………S182

Alpha-2 adrenergic…………………………S331, S332

Alpha-2 nicotinic receptors…………………………S373

Alpha7…………………………S96, S98, S106, S182, S183, S209

Alpha-7 nachr…………………………S184

Alpha7 neuronal nicotinic receptor…………………………S98

Alpha-lipoic acid…………………………S345

Alpha7 nicotinic receptor agonist…………………………S185

Alzheimer's…………………………S3, S4, S17, S25, S43, S44, S51, S52, S63, S64, S66, S92, S154, S172, S182, S184, S223, S227, S236, S254, S257, S269, S364

AM251…………………………S405

American Indian…………………………S369, S377

Amino acid neurotransmitter…………………………S136, S204

Amiodarone…………………………S181, S182

Amisulpride…………………………S175, S272, S430

AMPA…………………………S16, S17, S38, S53, S62, S72, S186, S218, S227, S239, S336

AMPA PAM…………………………S230

AMPA receptor…………………………S16, S17, S62, S72, S88, S186, S215, S218, S223, S227, S230, S336, S412

Amperometry…………………………S430

Amphetamine…………………………S9, S13, S15, S20, S48, S147, S195, S199, S212, S213, S287, S290, S311, S369, S375, S380, S426, S434, S437, S441

Amygdala…………………………S1, S2, S13, S16–S18, S21, S22, S24, S29, S33, S41, S49, S53, S54, S66–S69, S76, S78, S79, S82, S93, S94, S109–S112, S116, S119, S126, S140, S142–S145, S148–S151, S158, S161, S163, S174, S204, S214, S241, S242, S253, S265, S266, S268, S269, S277, S290, S295, S315, S317, S319, S326, S329, S335, S337, S339–S341, S361, S362, S368, S386, S388, S393, S394, S396, S399, S400, S402–S405, S412, S422, S432, S442

Amyloid imaging…………………………S154

Anabolic-androgenic steroids…………………………S369

Analysis…………………………S4, S5, S11, S15, S17, S19–S22, S26, S28, S29, S31, S36, S45, S46, S48, S51, S52, S54, S55, S57, S58, S60, S61, S64, S65, S68, S70, S77–S81, S84, S85, S88, S89, S91, S93, S95–S100, S102–S105, S107–S110, S112, S113, S116, S117, S120, S122, S126, S130, S132–S136, S140–S149, S152–S157, S160, S162–S165, S169, S171, S173, S174, S176, S179, S181, S182, S187, S192, S194, S196, S198, S199, S202–S204, S207, S208, S211–S214, S217–S219, S221–S224, S226, S227, S229, S232, S235, S239–S241, S244, S245, S248, S250, S254–S257, S259–S262, S264, S266–S268, S271, S274, S276, S277, S279, S280, S283, S285, S288–S291, S293, S295–S298, S300–S303, S305, S306, S309, S311, S312, S314, S319, S327, S329, S334–S336, S340–S342, S344, S346, S347, S352–S354, S356–S363, S365, S368, S369, S372–S376, S378–S381, S383–S391, S393–S399, S401–S405, S408–S410, S413, S414, S416–S423, S425, S426, S428, S429, S434, S437, S437, S445, S448

Anandamide…………………………S295, S383

Ancestry…………………………S46, S65, S132, S177, S259, S262, S374, S376, S378, S397, S423, S424

Anhedonia…………………………S28, S38, S41, S125, S178, S200, S201, S205, S213, S242, S391, S433

Animals…………………………S8, S9, S14–S19, S22, S24, S25, S39, S43, S45, S50, S55, S56, S58, S60, S63, S66, S68, S75–S78, S81, S86, S88, S90, S111, S114, S126, S146, S147, S149, S151, S158, S161, S164, S182–S184, S186, S188–S191, S193, S196, S197, S199–S208, S211–S213, S215–S217, S222, S266, S282, S305–S307, S309, S311–S313, S322, S325, S326, S332, S333, S337, S339, S342, S351, S363, S366, S373, S390, S396, S397, S406, S409, S414, S415, S430, S432, S433, S435, S439, S445, S447

Anorexia nervosa…………………………S47, S48, S265, S266, S297

Anterior cingulate…………………………S16, S20, S27, S36, S38, S49, S51, S53, S83, S109, S110, S115, S119, S126, S134–S136, S140–S142, S155–S157, S165, S194, S221, S256, S266, S268, S269, S271, S272, S274–S277, S279, S281, S283–S286, S288, S290, S302, S303, S312, S315, S319, S321, S322, S345, S362, S364, S381, S382, S384, S386–S394, S396–S398, S416, S424, S448

Antibodies…………………………S4, S14, S31, S37, S63, S88, S184, S242, S312, S340, S382

Anticipation…………………………S15, S52, S111, S115, S140, S145, S155, S210, S239, S242, S272, S273, S288, S347

Antidepressant…………………………S3, S16, S38, S39, S45, S57, S62, S65, S82, S83, S86, S87, S89, S117, S119, S139, S146, S161, S172, S200–S202, S204, S206, S224, S225, S231, S255, S263, S265, S295, S299, S300, S302–S304, S311, S327, S343–S347, S351–S354, S356, S360, S386, S394, S397, S402, S411–S413, S417, S419, S421–S424, S431, S432, S434, S435, S443, S446

Antioxidants…………………………S443

Antipsychotic…………………………S42, S64, S65, S83, S90, S95, S99, S100, S102–S107, S120, S121, S128, S132, S135, S167–S175, S182, S184, S186, S187, S200, S208, S210, S211, S221, S228, S232, S246, S247, S249–S251, S272, S274–S276, S291, S320, S334, S335, S349, S352, S356, S382–S384, S397, S424, S430, S435, S437, S438

Antipsychotic agents…………………………S98, S102, S107, S120, S186, S437

Antipsychotic drug…………………………S65, S104, S135, S171, S186, S187, S210, S320, S335, S354, S382

Antipsychotic response…………………………S132

Antipsychotic-naive…………………………S120

Antisocial personality disorder…………………………S385

Anxiety…………………………S2, S7, S18, S38, S47, S48, S54, S59, S60, S70, S73, S75, S76, S78, S80, S81, S83, S87, S90, S94, S101, S108–S111, S119, S122, S135, S136, S140, S141, S143, S144, S148, S160, S162, S163, S165, S172, S179, S193, S204, S214, S224–S226, S229, S241, S249, S250, S252–S256, S258, S265, S283, S287, S291, S296, S297, S301, S302, S304, S306, S307, S317, S331, S335, S341, S343, S347, S351, S354, S359, S371, S372, S376, S389, S395, S405, S407, S421, S443, S446, S448

Anxiety disorders…………………………S21, S23, S48, S49, S54, S69, S70, S81, S83, S90, S109–S112, S120, S139, S141, S142, S146, S153, S162, S163, S224, S225, S249, S250, S253, S256, S263, S306, S307, S422, S426, S442, S445

Anxiety-like behavior…………………………S76–S78, S80–S82, S252, S306, S327, S331, S341, S448

Anxiolytic…………………………S38, S77, S172, S177, S188, S200, S204, S304, S341, S352, S378, S405, S408, S421, S448

APOE…………………………S4, S14, S43, S63, S64, S254, S257, S261

APOE genotypes…………………………S254

APOE2…………………………S63, S64, S257

Appetitive…………………………S1, S35, S203, S204, S403, S406

ARC…………………………S8, S239, S258

Aripiprazole…………………………S105, S120, S174, S186, S228, S235, S345, S346, S349–S351, S356, S394, S424

Arthritis…………………………S159, S447

Asenapine…………………………S181, S352

Asian American…………………………S406

Asic1a…………………………S82

ASL…………………………S276, S394

Association…………………………S2, S3, S5, S8, S11, S17, S21–S24, S29, S38, S41, S43, S45, S47, S50–S52, S60–S62, S65, S66, S70, S77, S86, S93, S95, S102, S113, S115, S122, S124, S130–S137, S139, S143–S147, S152, S155, S158, S160, S161, S174, S176, S188, S198, S222, S225–S228, S230, S237–S239, S242, S245, S246, S248, S250–S252, S255–S260, S262, S263, S265, S277, S279, S283, S284, S291, S298, S301, S303, S305, S313, S315–S317, S323, S324, S337, S338, S343–S346, S355, S356, S361, S364, S366–S370, S373–S383, S389, S390, S392, S395, S401, S408, S417, S423, S424, S429, S434, S448

Association learning…………………………S111, S308, S325, S332, S364

Astrocytes…………………………S39, S40, S64, S86, S91, S200, S214, S319, S320, S333, S336, S383, S392

Attachment…………………………S118, S212, S361, S375, S405, S406

Attention…………………………S2, S6, S7, S23, S27, S28, S33, S36, S51, S56, S63, S66, S75, S80, S81, S83, S96, S98, S99, S106, S107, S111–S114, S116, S118, S121, S123, S141, S144, S145, S151–S156, S160, S163, S164, S171, S172, S175, S185, S188, S193, S196, S199, S204, S207, S209, S237, S239, S245, S247, S250, S260, S265, S274, S275, S286, S305, S309, S311, S313, S319, S333, S341, S349, S367, S368, S371, S388, S395, S399, S415, S417, S421, S428, S429, S437, S442

Attention bias…………………………S110, S349

Attention set shifting…………………………S75

Attentional training…………………………S144

Atypical antipsychotics…………………………S65, S96, S97, S102, S106, S132, S168, S174, S273, S301, S356, S430

Auditory…………………………S8, S33, S34, S51, S59, S72, S82, S118, S157, S169, S172, S182, S183, S195, S199, S241, S244, S245, S247, S276, S305, S321, S399, S442, S446

Auditory hallucinations…………………………S147, S156, S171

Autism…………………………S5, S10, S17, S25, S27–S31, S39, S40, S45–S47, S55, S60, S70, S84, S87, S116, S135, S150, S151, S198, S217, S229, S240, S259, S260, S308, S337, S405, S448

Autism spectrum disorder…………………………S27, S46, S70, S73, S84, S86, S229, S260, S307

Autobiographical memory…………………………S118, S142

Autonomic…………………………S53, S54, S147, S177, S309, S317, S385, S395, S409, S439

Autonomic nervous system…………………………S73, S80, S314

Avolition…………………………S41

Anxiety…………………………S2, S7, S15, S18, S21, S23, S24, S38, S47, S48, S49, S54, S59, S60, S69, S70, S73, S75, S76, S77, S78, S80, S81–S84, S88, S90, S92, S94, S102, S108, S109, S110–S112, S119, S120, S123, S125, S136–S137, S139–S144, S146, S148, S153, S160–S163, S166, S172–S173, S180, S194, S200, S202, S204, S207, S214, S224, S225, S226, S229, S241–S242, S245, S249, S250, S252–S256, S258, S259, S263, S266, S270, S272, S283, S287–S288, S291, S296, S298, S301, S302, S304, S306–S307, S317, S327, S330–S332, S335, S340–S341, S343, S347, S351, S354, S359, S371–S372, S376, S390, S392, S395, S405, S408, S421, S425, S433, S441–S442, S445–S448

Axon initial segment…………………………S219

B

Baby cry…………………………S118

Baclofen…………………………S34, S36, S47, S72, S290, S405, S428

BALB/cj…………………………S76

Basal forebrain…………………………S67, S93, S241

Basal ganglia…………………………S84, S189, S199, S268, S271, S321, S381, S392, S404, S417

Bath salts…………………………S441

BCG…………………………S88

BDNF…………………………S4, S18, S24, S35, S45, S54, S55, S57, S73, S200, S207, S208, S212, S213, S222, S253, S258, S328, S334, S341, S412, S413, S434, S91–S93, S125, S127, S149, S150

Behavior…………………………S2, S6, S9, S14, S15, S17–S19, S21, S23, S24, S28, S31, S35, S40, S41, S43, S48–S50, S55, S57, S59, S60, S63, S67, S68, S70–S72, S74, S77–S80, S82, S83, S86, S88, S90, S92, S94, S96, S109, S114, S118, S120, S121, S123, S126, S127, S130, S135–S138, S145, S148, S152, S153, S156, S158, S161, S164, S171, S178, S184, S189–S191, S193–S195, S197, S199–S205, S207, S210–S212, S215, S216, S219, S221, S227, S228, S230, S238, S245, S253–S255, S258, S261–S263, S266, S267, S270, S274, S275, S281–S285, S287, S288, S292, S297, S298, S304–S308, S310, S312, S313, S316–S318, S321, S322, S325–S327, S329–S333, S335, S338–S340, S343, S354, S357–S359, S363, S365–S367, S369, S371, S373–S375, S377, S379, S393, S405, S406, S416, S420, S421, S432–S435, S441, S443, S444, S448

Behavioral inhibition…………………………S5, S78, S109, S111, S307

Behavioral sensitization…………………………S190, S328

Behaviour therapy…………………………S13, S77, S77, S83, S118, S140, S144–S145, S162, S225–S226, S228–S229, S294, S349

Behavioural symptoms…………………………S162

Benzodiazepine…………………………S192, S310

Bereavement…………………………S358, S359

Beta adrenergic receptors…………………………S124–S125, S327–S328

Beta-arrestin…………………………S186, S437

Biomarker…………………………S4, S5, S10–S12, S63, S64, S75, S98, S115, S123, S128, S136, S139, S140, S159, S202, S227, S293, S386, S389, S390, S401, S407, S416, S424, S435, S448

Bipolar…………………………S5, S11, S15, S16, S39, S40, S44, S61, S62, S65, S68, S69, S89, S90, S114, S123, S124, S127, S128, S152, S153, S160–S162, S211, S220, S222, S239, S246, S247, S251–S253, S298, S299, S302, S303, S343, S345, S349, S354–S356, S358, S359, S383, S389, S391, S392, S396, S397, S400, S402, S411, S418–S421, S424, S426, S445

Bipolar disorder…………………………S5, S15, S28, S29, S38, S39, S42, S48, S56, S57, S60, S61, S68–S70, S90, S92, S113–S117, S123–S127, S132, S138, S147, S153, S160, S161, S172, S174, S182, S187, S207, S211, S215, S218–S220, S222, S238, S246, S247, S249–S253, S255, S265, S290, S294, S298, S308, S315, S337, S345, S349–S352, S354, S359, S368, S383, S387, S388, S394, S396, S398–S401, S416, S418–S421, S423, S424, S426, S437, S447

Bipolar major depressive episodes…………………………S419

Bipolar mania…………………………S215, S297, S352

Birth weight…………………………S70, S119, S147, S151, S163, S237

Bk channel…………………………S324

Blacks…………………………S370, S371

Blast…………………………S267, S291, S408

Blood pressure…………………………S12, S49, S80, S124, S178, S228, S251, S251, S308, S353, S426, S427

Blood vessels…………………………S91, S408

Body dysmorphic disorder…………………………S281, S425

Body mass index…………………………S19, S47, S102, S120, S136, S158, S237, S251, S252, S291

Body-image disorders…………………………S370

Bonding…………………………S72, S73, S361, S389, S405, S438

Borderline personality…………………………S269, S270, S375, S376, S446

BPRS…………………………S105–S107, S245, S386, S425

Brain…………………………S1–S3, S5–S7, S9, S10, S14, S15, S17–S24, S26–S42, S44–S52, S55–S64, S66–S69, S71, S73, S74, S75–S80, S82, S85–S92, S98, S109–S115, S117–S119, S123, S126, S128, S129, S134, S135, S137, S138, S140–S151, S153–S158, S161–S165, S171, S172, S176, S178, S179, S183–S185, S188, S191–S195, S197, S199–S204, S206–S214, S216–S219, S221–S225, S231, S235–S238, S240–S246, S248, S253–S256, S259, S261, S263, S264, S266–S293, S295, S296, S302, S303, S306, S307, S311–S313, S315, S317–S322, S324–S326, S329, S333, S335–S338, S340–S342, S345, S356, S361–S368, S372–S374, S378, S379, S381, S382, S384–S390, S392–S406, S408, S410, S413, S415, S416, S418, S422–S424, S428, S430, S431, S433–S438, S440, S441, S443–S448

Brain imaging…………………………S3, S5, S47–S49, S63, S149, S267, S289, S394, S403, S448

Brain metabolism…………………………S267, S392, S407

Brain network…………………………S109, S149, S273, S282, S396

Brain neural network formation…………………………S341

Brain stimulation…………………………S47, S53, S331, S409, S442

Brain-computer interface…………………………S163

Brainstem…………………………S7, S110, S150, S179, S402, S403, S415, S440, S448

Bromodeoxyuridine…………………………S85, S339

Bulimia nervosa…………………………S48, S260

Bupropion…………………………S206, S303, S374, S378, S379, S417, S422

Buspirone…………………………S13, S188

Butyrylcholinesterase…………………………S14, S223, S312

C

C-FOS…………………………S78, S183, S200, S203, S217, S334, S335, S412

C-reactive protein…………………………S136, S354

C57…………………………S22, S76, S77, S126

C57BL/6J mice…………………………S87, S329, S340, S393

CA1…………………………S7, S8, S84, S137, S223, S278

CAG length…………………………S262

Calbindin…………………………S32, S55, S57, S429

Calcium…………………………S4, S17, S45, S54, S55, S57, S61, S77, S89, S194, S310, S333, S336, S437

Calcium sensors…………………………S194

Calretinin…………………………S32, S204, S205

cAMP…………………………S185, S186, S223, S258, S336, S424, S437, S440

Candidate genes…………………………S21, S130, S131, S132, S253, S261, S376

Cannabinoid…………………………S95, S177, S194, S273, S312, S367, S405

Cannabis…………………………S49, S94, S113, S243, S273, S301, S312, S377, S383, S384, S405

Cannabis abuse…………………………S301

Cannabis use status…………………………S243

Cardiovascular disease…………………………S12, S52, S80, S91, S121, S136, S174, S250, S314, S424, S443

Catalepsy…………………………S186, S187, S305, S335

Catecholamines…………………………S21, S80, S127, S304

Catechol-O-methyltransferase…………………………S123, S209, S237, S246

Cathinone…………………………S441

Caudate…………………………S19, S48, S112, S115, S118, S125, S141, S143, S150, S155, S157, S173, S242, S267–S269, S278, S283, S288, S290, S291, S365, S381, S382, S386, S387, S391, S394, S397, S398, S402, S404, S413

CB1…………………………S47, S94, S132, S194, S295, S405, S405, S443

CBT…………………………S117, S139, S144, S225, S294

CCK…………………………S82, S132

CD-1 mouse…………………………S88, S206, S222

CD4…………………………S86, S89, S288, S305

CDH2…………………………S255

CDP-choline…………………………S97, S106

Cell adhesion…………………………S259, S337

Cell death…………………………S2, S64, S91, S207, S212, S215, S273

Cellular…………………………S9, S13, S15, S16, S18, S21–S23, S32, S38, S40, S43–S45, S55, S56, S64, S72, S89, S125, S137, S196, S200, S203, S208, S218, S220, S222, S259, S260, S264, S292, S307, S322, S335, S336, S338, S340, S342, S366, S434, S442, S446

Cellular transplantation…………………………S341

Central raters…………………………S106

Cerebellum…………………………S20, S55, S58, S61, S82, S112, S125, S151, S154, S157, S173, S218, S223, S239, S253, S263, S265, S268, S272, S273, S279, S286, S361, S393, S402

Cerebral blood flow…………………………S221, S273, S289, S319

Cerebral cortex…………………………S31, S32, S122, S134, S157, S202, S203, S207, S219, S258, S393

Cerebrospinal fluid…………………………S138, S234, S293, S317, S383, S417, S429, S435

Cessation…………………………S171, S179, S200, S322, S329, S379, S380

C-Fos…………………………S78, S183, S200, S203, S217, S334, S335, S412

CGI-I…………………………S98, S99, S102, S107, S224–S226, S228, S344, S346, S422

CDH13…………………………S380

Chemical biology…………………………S220

Child…………………………S11, S29–S31, S48, S49, S74, S76, S102, S109, S118–S120, S135, S150–S152, S160, S162, S198, S222, S229, S232, S238, S241, S250, S251, S259, S262, S264, S287, S296, S297, S350, S357, S388, S389, S393, S398, S407, S420

Childhood…………………………S5, S10, S18, S32, S108, S111, S113, S120, S127, S141, S149, S163, S222, S232, S237, S238, S243, S249, S256–S258, S261–S262, S370, S371, S380, S406, S408, S409, S442

Childhood abuse…………………………S145, S262

Childhood adversity…………………………S257, S371

Childhood maltreatment…………………………S148, S243, S257, S262

Childhood trauma…………………………S23, S24, S48, S127, S142, S146, S149, S150, S256, S257, S258, S262, S287, S288, S371, S408

Children…………………………S2, S7, S10, S30, S31, S46, S49, S67, S70, S78, S84, S102, S108, S116, S118–S120, S124, S128, S129, S136, S140, S146, S148–S153, S155–S158, S163, S228, S229, S237, S249, S252, S261, S263, S264, S270, S273, S296, S306, S310, S326, S349, S350, S359, S387, S388, S393, S399, S406, S407

Cholesterol…………………………S101, S168, S172, S174, S175, S306, S424, S443

Cholinergic…………………………S47, S62, S67, S93, S96, S106, S199, S236, S320, S326, S341, S379, S422, S423

CHRNA3…………………………S373, S377, S379

CHRNA5…………………………S284, S372, S373

Chronic…………………………S7, S13, S14, S28, S37, S38, S62, S63, S66, S73, S75, S79, S82, S85, S87–S90, S92, S97, S100, S101, S106, S130, S132, S134, S137, S139, S145, S153, S159, S161, S165, S166, S169, S171, S172, S174, S187–S192, S194, S195, S199–S205, S211, S215, S226, S229, S245, S246, S248, S250, S252, S255, S258, S265, S269, S272, S274, S276–S278, S282, S283, S286, S288, S290, S291, S295, S306, S308, S314, S322, S324, S326, S328, S329, S331–S333, S339, S340, S342, S364, S366, S367, S372, S374, S381, S382, S384, S387, S392, S404–S408, S410, S412, S415, S418, S431, S434, S443, S444, S447, S448

Chronic early neglect…………………………S406

Chronic pain…………………………S1, S17, S36, S37, S124, S159, S234, S309, S311

Cigarette smoking…………………………S20, S175, S287, S376, S404

Cingulate…………………………S35, S49, S53, S57, S58, S110, S140, S147, S157, S241, S267, S270, S341, S386, S394, S400, S402, S407

Cingulate gyrus…………………………S54, S141, S171, S254, S318

Cingulum…………………………S156, S157, S191, S243

Circadian rhythms…………………………S15, S92, S217, S324, S330

Citalopram…………………………S57, S119, S121, S300, S304, S346, S349, S358, S430

CK-1…………………………S375

Clinical…………………………S1–S3, S5, S10–S14, S16, S24–S26, S28, S30, S34, S36, S37, S40, S41, S43–S45, S52, S57–S60, S62, S64–S67, S69, S70, S72, S75, S77, S84, S88–S90, S94–S105, S109–S111, S113–S118, S120–S123, S127–S130, S132–S136, S138, S139, S141, S144, S146, S150, S152, S153, S157, S159–S176, S178–S182, S184, S187, S189, S192, S195, S196, S201, S203–S205, S208, S210, S224–S233, S236, S237, S239, S240, S245–S247, S249–S252, S255, S260, S261, S263, S268, S270, S272, S273, S276–S280, S282, S284, S287, S291–S307, S309, S317, S320, S330, S334, S335, S337, S342–S349, S351, S352, S354, S356–S360, S367, S370–S374, S379–S384, S386, S388–S390, S394, S395, S397, S399, S400, S402, S405, S408–S411, S413, S414, S416–S425, S427, S428, S431, S432, S435–S438, S444, S446, S448

Clinical decision making…………………………S349, S351

Clinical features…………………………S29, S162, S239, S388

Clinical global impression scale…………………………S345, S352

Clinical high risk…………………………S10, S11, S241, S245, S278, S384, S409

Clinical staging…………………………S418

Clinical trial…………………………S3, S14, S34, S37, S69, S96, S102, S106, S122, S123, S133, S135, S142, S166, S186, S230, S231, S235, S240, S284, S289, S300, S346, S347, S349, S357, S360, S361, S378, S380, S394, S404, S412, S421–S425

Clinical trial methodology…………………………S231, S361

CLOCK…………………………S15, S137, S138, S330, S331

Clock…………………………S92, S330, S331

CLOCK gene…………………………S330, S331

Clonidine…………………………S169, S181, S331, S332

Clozapine…………………………S121, S132, S169–S171, S175, S183, S184, S186, S208, S210, S215, S434, S438

CNTNAP2…………………………S29, S198, S259, S260

CNV…………………………S28, S29, S46, S60, S61, S62, S84, S259, S260, S264, S292

Cocaine…………………………S2, S7, S9, S13–S15, S21, S28, S35, S36, S47, S50, S67, S157, S158, S165, S166, S177, S180, S189–S194, S196, S197, S211, S216, S286, S290, S311–S313, S316, S319, S322, S325, S327–S334, S338, S342, S371, S377, S378, S402–S405, S426, S427, S432, S433, S440, S441

Cocaine addiction…………………………S14, S15, S28, S286, S312, S330, S331, S338, S339, S376, S402

Cocaine dependence…………………………S6, S157, S176, S285, S331, S334, S370, S371, S403, S425

Cocaine self-administration…………………………S9, S13–S15, S50, S188, S190–S192, S316, S322, S328–S331, S333, S334, S339

Cocaine toxicity…………………………S312

Cocaine-seeking behavior…………………………S15, S189, S192, S310, S311, S327, S330, S331

Cochrane review…………………………S359

Cognition…………………………S4, S6, S8, S13, S20, S22, S26, S31, S63, S66, S67, S91, S94, S96, S99, S106, S117, S131, S134, S157, S170–S173, S175, S182, S184, S209–S211, S215, S220, S224, S236, S237, S242, S247, S274, S276, S278, S281, S282, S293, S317–S320, S341, S350, S366, S374, S382, S392, S407, S435–S437, S439

Cognitive and Physical Functioning Questionnaire…………………………S347, S416

Cognitive behavioral therapy…………………………S117, S139, S144, S225, S294

Cognitive control…………………………S28, S112, S155, S195, S199, S281, S286, S365, S366, S385

Cognitive function…………………………S4, S48, S49, S70, S75, S81, S95, S96, S113, S115, S116, S161, S169, S171, S177, S188, S209, S210, S215, S217, S231, S237, S243, S246, S274, S281, S287, S321, S350, S351, S362, S366, S419

Cognitive impairment…………………………S3, S4, S100, S107, S108, S114, S116, S118, S172, S182, S183, S185, S217, S233, S236, S243, S276, S279, S305, S368, S386, S431, S437

Cognitive reappraisal…………………………S109, S269, S289

Cognitive therapy…………………………S139, S162

Cognitive training…………………………S143, S247, S248, S439

Comorbidity…………………………S69, S80, S111, S149, S159, S252, S259, S276, S277, S288, S315, S334, S341, S359, S370

Comparative effectiveness…………………………S349, S354

Compensation…………………………S43, S100, S126, S130, S171, S174, S206, S254, S264, S280, S348, S413, S416, S425

Complicated grief…………………………S406, S349, S358, S359, S406, S407

Compulsive…………………………S7, S9, S28, S40, S47, S75, S79, S164, S226, S297, S308, S310, S338, S339

Computational…………………………S27, S48, S72, S194, S207, S310, S321, S365

COMT…………………………S21, S22, S49, S124, S126, S209, S210, S238, S247, S286, S297, S320, S337, S338, S379

COMT inhibitor…………………………S209, S210, S297

Conditioned cues…………………………S322

Conditioned place preference…………………………S13, S36, S81, S193, S217, S316, S325, S327, S330, S332, S339, S440

Conditioning…………………………S17, S18, S21, S23, S50, S54, S55, S56, S67, S78, S130, S140, S143, S196, S212, S217, S223, S295, S308, S314, S316, S327, S332, S439

Conflict…………………………S11, S43, S54, S60, S108, S109, S136, S140, S141, S160, S221, S230, S271, S272, S287, S355, S365, S365, S396

Cognition…………………………S4, S6, S8, S20, S22, S26, S31, S33–S34, S63, S66–S67, S91, S95–S96, S99–S100, S107, S117, S118, S132, S135, S147, S157, S170–S172, S174, S176, S183, S209–S211, S220, S224, S237, S271, S274, S277–S279, S281–S282, S294, S318, S320–S321, S341, S351, S361, S366, S375, S382, S385, S393, S407, S435, S437, S439

Connectivity…………………………S5, S16, S23, S29, S30, S36, S39, S41, S68, S69, S93, S110, S112, S113, S144, S145, S147–S150, S152, S154, S155, S157, S192, S238, S254, S255, S265, S270, S271, S273, S277, S281, S282, S290, S318, S320, S321, S362, S368, S381, S386, S389, S394, S397–S401, S446

Consolidation…………………………S1, S82, S190, S235, S267, S447

Context…………………………S5, S9, S17, S28, S36, S44, S54, S63, S78, S79, S82, S110, S129, S143,S152, S158, S159, S174, S178, S186, S187, S189, S217, S218, S225, S245, S254–S255, S260, S262, S263, S264, S270, S271, S274, S275, S278, S299, S310, S317, S327, S328, S331, S352, S357–S359, S386, S396, S406, S414, S424, S444

Context processing…………………………S245, S270

Contextual factors…………………………S349

Control…………………………S4–S6, S8, S11, S15–S19, S22, S28–S32, S34, S40, S42–S50, S52, S54, S61, S62, S65, S66, S68, S71, S77, S80, S81, S83–S85, S88–S92, S94, S109–S113, S118, S119, S123, S134, S136–S139, S141, S142, S144, S147, S148, S150, S151, S153, S154, S156–S159, S164, S170, S190–S192, S195, S199–S202, S205, S207, S209, S213, S216–S220, S222, S224, S225, S227, S230, S231, S237–S241, S244–S248, S258, S259, S264, S266, S268, S270, S275, S277, S279, S281–S283, S285, S287–S290, S292, S297, S302, S303, S306, S311, S313, S315, S317, S319–S322, S325, S330, S333, S335–S340, S352, S362, S363, S365, S366, S368, S371–S373, S375, S376, S383–S387, S390, S393, S395–S398, S400, S402, S403, S405, S408–S410, S413, S415, S419, S423, S428, S432, S438–S440, S442–S447, S449

Copy number variation…………………………S29, S46, S60, S292

Corpus callosum…………………………S34, S152, S275, S288, S397–S398

Correlation…………………………S19, S51, S62, S70, S89, S90, S102, S110, S111, S122, S131, S136, S153–S155, S161–S163, S201, S219, S231, S238, S241, S248, S265, S270, S271, S273, S277, S290, S292, S293, S315, S326, S354, S361, S368, S380, S384–S386, S389, S390, S394, S396, S398, S400, S413, S429

Cortex…………………………S1, S5, S7, S15, S16, S20–S22, S26–S28, S32–S36, S38, S40, S42, S44, S45, S49, S50, S53, S55, S57, S58, S61–S63, S68, S71–S73, S77–S80, S82–S84, S89, S90, S92, S109, S110, S113–S115, S119, S123, S126, S127, S134–S136, S138, S140–S142, S145, S146, S148, S150–S152, S154, S155, S157, S163, S165, S166, S174, S180, S182, S184, S185, S192–S196, S200, S203–S205, S207, S209, S210, S212, S213, S215, S219–S221, S223, S231, S238, S241–S243, S246, S253, S255–S257, S264–S272, S274, S275, S278–S282, S285, S286, S288, S290, S295, S297, S302, S307, S310–S312, S315, S318, S319, S325, S327, S328, S332, S333, S335, S337, S340–S342, S361–S366, S368, S382, S384–S388, S390–S394, S396–S403, S408, S411, S416, S423, S424, S430, S434, S436, S440, S445, S447–S448

Cortical development…………………………S156, S219

Cortical dopamine…………………………S20, S320

Cortical thickness…………………………S280, S389

Corticosterone…………………………S19, S43, S54, S202, S324, S341

Corticotropin…………………………S81, S126, S203, S212, S327

Corticotropin-releasing hormone …………………………S43, S262

Cortisol…………………………S3, S49, S110, S145, S159, S160, S177, S257, S262, S315, S354, S378, S400, S406–S409

Cortisol awakening response…………………………S110, S406, S407

COX-2…………………………S92, S337

CPFQ…………………………S416, S417

CPT…………………………S98, S152

Craving…………………………S7, S13, S20, S28, S165, S166, S178, S235, S283, S322, S333, S339, S367, S377–S379, S384, S428

C-reactive protein…………………………S354

CRF…………………………S55, S56, S76–S78, S81, S167, S203, S204, S327, S328, S331, S332

CRH…………………………S43, S172, S262, S263, S378

CSF…………………………S4, S11, S34, S48, S63, S128, S139, S154, S160, S288, S293, S326, S435

Csf oxytocin…………………………S160

Cue reactivity…………………………S20, S284, S311

Cues…………………………S6, S20, S28, S50, S52, S54, S78, S109, S114, S144, S164, S165, S199, S211, S239, S272, S284, S289, S319, S322, S323, S326, S331, S332, S339, S361, S363, S403, S404, S428, S439

Cyclic GMP…………………………S432

Cyclothymic disorder…………………………S252

Cynomolgus macaque…………………………S408

Cytokine…………………………S30, S43, S86, S88, S202, S264, S300, S317, S392

Cytokines…………………………S37, S38, S86, S88, S125, S137,S202, S264, S315, S317

D

D1…………………………S6, S13, S36, S41, S90, S190, S213, S214, S333, S366, S383, S432, S440, S441, S443

D2…………………………S9, S13, S22, S47, S84, S95, S173, S213, S214, S302, S327, S333, S366, S375

D2 receptor…………………………S9, S10, S22, S50, S173, S286, S320, S333, S366, S379

D2/D3…………………………S198, S199, S268, S308

D2R ligands…………………………S187

D3…………………………S13, S199

D3 dopamine receptors…………………………S268, S308

D3 receptor…………………………S13

D4…………………………S13, S309

D5…………………………S13, S333

D-amphetamine…………………………S20, S58, S426

D-amphetamine prodrug…………………………S100

D-Serine…………………………S58, S59, S208, S214, S304

DARPP-32…………………………S213, S220, S221, S375, S381

DASB…………………………S282

DBS…………………………S18, S19, S90, S122, S123, S166, S343

De novo mutation…………………………S60, S250, S259, S260

Decision making…………………………S27, S28, S122, S297, S351

Deep brain stimulation…………………………S18, S28, S90, S166, S343

Default mode…………………………S154, S270

Default mode network…………………………S144, S156, S270, S362

Deficit…………………………S11, S32, S35, S42, S43, S47, S66, S76, S80–S83, S91, S95, S98, S151, S153, S155, S156, S160, S179, S182–S185, S199, S200, S209, S210, S213, S237, S240, S247, S258, S265, S275, S280, S288, S305, S312, S314, S319–S321, S436

Deltafosb…………………………S47

Dendrites…………………………S6, S220, S221

Dendritic morphology…………………………S208

Dendritic spines…………………………S40, S81, S84, S85, S217, S329, S339, S341

Denicotinized tobacco…………………………S404

Dependence…………………………S7, S50, S116, S139, S164, S176, S179, S180, S188, S191, S195, S243, S277, S284, S291, S292, S306, S324, S329, S331, S332, S334, S340, S341, S367, S369–S371, S377, S378, S380, S404, S405, S427

Depressed…………………………S15, S16, S38–S40, S45, S83, S88, S89, S91, S93, S94, S115, S117–S120, S122, S124, S136–S138, S159, S161, S162, S172, S200, S203–S205, S229, S230, S247, S295, S298, S300, S301, S304, S331, S345, S346, S348, S354, S356, S357, S360, S365, S387, S389, S390, S395–S397, S399, S400, S411–S413, S420, S424

Depression…………………………S3, S12, S15, S16, S18, S19, S28, S37–S40, S42–S45, S48, S56, S57, S62, S65, S69, S70, S78, S81–S83, S85, S86, S88–S91, S93, S94, S98, S99, S101, S109, S111, S115, S117–S119, S122–S128, S136–S140, S143, S144, S146, S148, S149, S159, S161–S163, S169, S172, S173, S176, S200–S205, S227, S229–S231, S235, S238, S239, S250, S252, S256, S259, S261, S263, S264, S266, S267, S282, S284, S290, S294–S296, S298–S305, S308, S311, S315, S317, S321, S325, S334, S335, S342–S354, S356–S360, S365, S371, S373, S386–S390, S392, S395, S396, S398, S400–S402, S406, S411–S415, S417–S426, S430–S434, S437, S443, S444, S447, S448

Depressive phenotype…………………………S88, S204

Designer drug…………………………S216

Desipramine…………………………S79, S80, S304

Desvenlafaxine…………………………S296

Development…………………………S2, S4, S5, S9–S12, S14, S15, S17, S18, S21–S27, S30, S32, S33, S36, S39, S40, S42–S45, S47–S50, S54, S56, S57, S59, S60, S63, S67, S69, S70, S73, S76, S79, S83–S90, S95, S98, S100–S102, S104, S106, S108, S109, S115, S118, S120, S123–S126, S131–S133, S135, S137–S139, S141, S142, S145–S149, S151, S152, S154, S158, S159, S164, S166, S167, S171, S174, S180, S184, S191, S193, S194, S201, S202, S205, S206, S208–S220, S222, S224–S227, S230, S231, S235–S238, S240, S242, S248–S251, S253, S258, S259, S261, S263–S265, S270, S273, S275, S284, S285, S287, S292, S295, S296, S298–S301, S303, S304, S311, S313, S315, S317, S323, S324, S326, S327, S332–S334, S336–S339, S341, S344, S346, S349–S351, S353, S354, S356–S358, S362, S366, S367, S372, S374, S380, S381, S384, S385, S387, S388, S390, S394, S403, S405–S407, S410, S412, S414, S416–S418, S430–S435, S437–S439, S443, S446, S447

Developmental programming…………………………S59

Dex/CRH test…………………………S257

Diabetes…………………………S12, S52, S121, S159, S174, S175, S208, S387, S388

Diagnosis…………………………S2, S11, S20, S23, S26, S30, S38, S93, S94, S98, S105, S111, S112, S115, S120, S126, S128, S130–S132, S134–S136, S141, S150, S152, S153, S155, S159, S163, S168, S172–S174, S211, S232, S235, S243, S246, S247, S249, S250, S257, S261, S262, S265, S269–S271, S275, S277, S280, S309, S321, S352, S354, S356, S376–S379, S383–S385, S391, S448

Diagnostic criteria…………………………S2, S226, S252, S367, S369

Diet…………………………S8, S9, S47, S161, S175, S193, S194, S207, S208, S229, S336, S337, S348

Difficult-to-treat…………………………S356

Diffusion imaging…………………………S156, S393, S396

Diffusion spectrum imaging…………………………S151

Diffusion tensor imaging…………………………S146–S148, S152, S153, S156, S157, S275, S280, S293, S333, S393, S398, S399, S401

Dimensions…………………………S2, S3, S6, S36, S139, S188, S214, S279, S292, S316, S367–S368

Disability…………………………S39, S46, S84, S105, S106, S115–S117, S156, S233, S244, S250, S252, S259, S260, S281, S282, S303, S315, S347, S371

DISC1…………………………S8, S22, S128, S129, S214, S219, S263

Discontinuation…………………………S58, S65, S101, S102, S135, S136, S168, S173, S175, S176, S223, S303, S345, S347, S349, S350, S353, S419, S420

Disgust…………………………S108

Disinhibition…………………………S21, S158, S211, S227, S416

Dispersion…………………………S275

DKO…………………………S312

DNA methylation…………………………S18, S22, S26, S73, S78, S92, S254, S327, S372

Dopamine…………………………S6, S9, S13–S15, S19–S22, S35, S41, S47–S50, S54, S72, S73, S75–S78, S83, S84, S90, S92, S95, S100, S107, S143, S153, S155, S178, S179, S182, S184–S187, S189–S192, S195, S196, S198, S199, S203–S206, S209, S213, S216, S218, S221, S224, S225, S235, S238, S239, S242, S245, S247, S261, S268, S269, S272, S273, S276, S284, S286–S288, S290–S292, S297, S303, S305, S308–S310, S318, S319, S322, S325, S328, S330, S333, S334, S338, S340, S363, S374, S376, S378, S379, S381, S383, S384, S397, S398, S402, S404, S405, S414, S415, S431, S432, S437, S438, S440, S442–S444, S446

Dopamine beta hydroxylase…………………………S83, S376

Dopamine D3…………………………S13

Dopamine neurons…………………………S35, S54, S92, S178, S192, S205, S267

Dopamine receptor D1…………………………S383

Dopamine receptor D2…………………………S213, S268, S308, S330, S382, S402, S438

Dopamine receptors…………………………S13, S213, S216, S268, S308, S383

Dopamine transporter…………………………S41, S60, S189, S215, S339, S340, S379

Dorsal hippocampus…………………………S189

Dorsal raphe…………………………S59, S86, S203

Dorsal raphe nucleus…………………………S409

Dorsolateral prefrontal cortex…………………………S8, S26, S32, S34, S89, S114, S126, S164, S220, S222, S242, S248, S265, S266, S270, S271, S275, S276, S279, S281, S286, S290, S366, S382, S385

Dorsolateral striatum…………………………S216, S308, S330

Dorsomedial striatum…………………………S216, S330, S338

Dosage…………………………S14, S148, S161, S168, S175, S228, S410, S411, S421

Dot probe…………………………S111

Double-blind…………………………S7, S24, S37, S44, S62, S67, S95–S104, S106–S108, S113, S127, S128, S136, S159, S161, S168, S170, S173, S176, S178, S179, S195, S223–S227, S229–S234, S274, S283, S297, S299–S301, S303, S304, S342, S344–S346, S348–S353, S356, S357, S360, S367, S378, S380, S404, S415, S422, S423, S426–S429, S440

Double-blind trial…………………………S102, S229, S232

Down syndrome…………………………S154

DRD2…………………………S22, S132, S320, S321, S337, S338, S379, S380

DRD4…………………………S261, S262, S368, S369, S379

DRD4 gene…………………………S379

DREADD…………………………S216

Drinking…………………………S7, S12, S52, S166, S178, S181, S188, S189, S194, S200, S208, S235, S253, S283, S284, S306, S324, S325, S329, S338, S340, S341, S366, S382, S428–S429

Drug abuse…………………………S50, S144, S177, S180, S189, S225, S226, S230, S238, S287, S288, S303, S311, S322, S326, S339, S344, S353, S355, S368–S370, S373, S403, S417

Drug combination…………………………S421

Drug cues…………………………S216, S322

Drug dependence…………………………S6, S235, S283, S330, S334, S373

Drug development…………………………S10, S24, S25, S36, S37, S59, S92, S98, S202, S225, S226, S229, S231, S246, S277, S294, S310, S329, S357, S358, S361, S382, S395, S419

Drug development tools…………………………S358

Drug self-administration…………………………S50, S78, S189, S192, S216, S287, S322, S339

Drug therapy…………………………S139, S146, S163, S218, S263

D-serine…………………………S58, S59, S208, S214, S304

DSM-5…………………………S2, S226, S252

DTI…………………………S3, S5, S6, S10, S23, S41, S51, S146–S148, S152, S156, S157, S191, S243, S244, S268, S271, S273, S275, S277, S281, S292, S393, S396–S398

Dual receptor antagonism…………………………S319

Duration of untreated psychosis…………………………S104

Dynamic causal modeling…………………………S145, S320

Dynorphin…………………………S216, S433, S439, S441

Dysbindin…………………………S22, S213, S444

Dysphoria…………………………S200, S440

E

Early age-at-onset…………………………S60, S123

Early life stress …………………………S126, S255, S257, S327

Early loss…………………………S158

Eating disorders…………………………S19, S55, S261

Ecstasy…………………………S282, S342, S427

ECT…………………………S57, S117, S122, S172, S230, S231, S363, S386, S399, S409, S410–S412, S433

Educational attainment…………………………S370

EEG…………………………S3, S24, S32, S33, S44, S72, S94, S163, S195, S200, S212, S234, S240, S248, S314, S385

Efficacy…………………………S7, S11–S14, S34, S36, S37, S39, S42–S45, S58, S62, S64, S69, S72, S75, S80, S83, S96–S98, S100–S102, S106, S107, S120, S122, S127, S131, S155, S161–S163, S167, S169, S170, S173, S175, S178, S178, S181–S183, S186, S187, S192, S204–S206, S212, S223–S227, S229–S231, S233, S235, S274, S276, S285, S296–S299, S301–S304, S307, S311, S317, S319, S331, S332, S335, S343–S349, S351–S354, S356, S357, S359, S360, S403, S410–S412, S418, S419, S421, S424, S432, S434, S435, S437, S443, S445

Egr3…………………………S183, S184

Electroconvulsive therapy…………………………S116, S156, S386, S399, S409–S411, S433

Electrophysiology…………………………S56, S60, S89, S182, S194, S196, S210, S310, S329, S366

Elevated plus maze…………………………S75, S77, S80, S90, S200, S304, S306, S331, S335, S431, S433, S445, S448

EMG…………………………S141

Emotion…………………………S6, S22, S23, S33, S34, S41, S53, S68, S69, S73, S80, S81, S87, S109, S113, S116, S130, S131, S134, S140, S144, S148, S153, S153, S155, S157, S248, S264, S269, S319, S361, S388, S392, S395, S399, S401, S405, S406, S423, S427, S438, S444

Emotion regulation…………………………S68, S153, S164, S269, S401

Emotional processing…………………………S96, S109, S139, S153, S157, S177, S265, S318, S427

Emotional stimuli…………………………S21, S68, S109, S139, S143, S177, S395, S422, S423, S426

Endocannabinoid…………………………S95, S194, S295, S383, S405, S442

Endocannabinoid system…………………………S95, S295, S383, S405

Endophenotype…………………………S30, S52, S63, S70, S123, S129, S130, S133, S134, S244, S256, S264, S265, S311, S375, S405

Endothelial functioning…………………………S97

ENT1…………………………S338

Environment…………………………S12, S27, S37, S49, S50, S110, S127, S148, S151, S158, S162, S192, S204, S217, S253, S258, S261, S267, S309, S316, S318, S322, S327, S359, S373, S394, S415, S427, S439

Environmental enrichment…………………………S78, S160, S316

Enzyme…………………………S14, S15, S22, S42, S83, S126, S127, S132, S180, S209, S238, S261, S297, S312, S313, S342, S379, S384, S429, S442, S448

Epidemiology…………………………S69, S70, S226, S370

Epigenetic…………………………S5, S17, S18, S22, S23, S26, S27, S37, S44, S55, S73, S78, S92, S123, S130, S202, S250, S258, S265, S327, S335, S337, S341, S372

Epigenome…………………………S263, S292, S327

ERK…………………………S56, S79, S80, S336, S431, S443

ERP…………………………S28, S33, S59, S125, S144, S245, S248

Escalation…………………………S14, S15, S95, S153, S187, S329, S334, S339, S422, S441

Escitalopram…………………………S3, S296, S301, S346, S351, S394, S416, S422, S422

Estrogen…………………………S23, S73, S200, S201, S257, S268, S317, S407, S408

Ethanol…………………………S79, S178, S188, S189, S191, S194, S195, S306, S312, S324, S325, S329, S332–S334, S338, S340–S342, S366, S372, S373, S375, S428

Ethanol-infusion…………………………S177

Evoked responses…………………………S36, S196, S321

Evolution…………………………S1, S10, S52, S172, S263

EVP-6124…………………………S171, S185

Excitability…………………………S37, S84, S90, S165, S194, S210, S212, S216, S306, S329, S331, S338, S341

Executive…………………………S6, S52, S114, S115, S123, S157, S172, S176, S199, S243, S246, S272, S276, S277, S320, S350, S353, S366, S368, S399, S402

Executive dysfunction…………………………S114, S158, S235, S320, S353

Executive function…………………………S3, S5, S28, S66, S83, S98, S114, S116, S135, S152, S171, S175, S176, S200, S237, S265, S276, S286, S320, S350, S351, S353, S367, S398

Executive function impairment…………………………S357

Exercise…………………………S94, S100, S160, S174, S357, S413, S424

Exome sequencing…………………………S29, S46, S65, S123, S259, S260

Expectation bias…………………………S94

Expression…………………………S2–S5, S8, S9, S14, S16–S19, S21–S24, S26, S30–S32, S35–S38, S40, S42–S44, S47, S48, S50, S54–S56, S60–S64, S67, S68, S70–S74, S76–S86, S88–S92, S94, S97, S109, S116, S122–S124, S128, S132, S134, S135, S138, S141, S142, S144, S161, S172, S184, S185, S187–S191, S193, S197, S198, S200, S201, S203–S205, S207, S208, S211–S223, S239, S256–S259, S262, S264, S265, S271, S279, S293, S306, S307, S310, S311, S314, S317, S322, S323, S325, S326, S329, S331, S333–S338, S341, S342, S361, S372–S375, S378, S381–S384, S393, S400, S402, S403, S405, S409, S413, S423, S430, S431, S433, S434, S440, S443–S445, S447

Extended amygdala…………………………S7, S81, S118, S241, S441

Extinction…………………………S1, S11, S14, S18, S19, S23, S35, S50, S54, S55, S67, S77, S83, S84, S141–S144, S190, S191, S193, S194, S211, S257, S263, S296, S313, S314, S322, S325–S328, S330, S332, S339, S364, S403

Eye-tracking…………………………S27

F

Face processing…………………………S33, S144, S248, S387, S395

Faces…………………………S5, S22, S29, S33, S69, S108, S109, S116, S140, S144, S153, S178, S248, S318, S388, S395, S401

Facial affect…………………………S33, S96, S116, S123, S248, S439

Factorial design…………………………S186, S349

FAM111A…………………………S373

Familial risk…………………………S68, S119, S389, S409

Familiarity…………………………S41

Family…………………………S11, S20, S30, S39, S41, S62, S68–S70, S77, S80, S90, S100, S102, S119, S124, S129, S133, S147, S171, S181, S190, S194, S199, S221, S243, S246, S252, S254, S260, S263, S264, S268, S269, S273, S278, S283, S292, S300, S309, S310, S317, S325, S335, S342, S363, S370, S374, S375, S381, S391, S400, S401, S407, S413, S414, S439

Family history alcoholism…………………………S283

Family studies…………………………S46, S70, S254

Family therapy…………………………S401

Fast-scan cyclic voltammetry…………………………S81, S203, S216, S363

Fat intake…………………………S261

Fatigue…………………………S112, S136, S178, S199, S228, S251, S346, S347, S391, S407, S416, S447

Fear…………………………S1, S2, S11, S16–S19, S21, S23, S34–S36, S53–S55, S60, S77–S79, S82, S108, S111, S118, S141–S144, S153, S217, S225, S256, S296, S313, S314, S318, S335, S364, S388, S406, S407, S447

Fear conditioning…………………………S16–S18, S21, S23, S54, S55, S66, S72, S79, S80, S82, S83, S110, S141, S143, S212, S217, S218, S223, S296, S313, S314, S363

Fear extinction…………………………S35, S55, S77, S80, S143, S144, S314

Feast…………………………S19, S399, S410, S411

Feedback…………………………S12, S49, S54, S95, S111, S118, S164, S190, S241, S242, S262, S266, S290, S309, S319, S329, S365, S393, S402, S410

Female…………………………S5, S55, S56, S70, S72, S93, S107, S121, S124, S127, S129, S131, S134, S138, S140, S141, S145, S146, S153, S155, S158, S159, S165, S167, S176, S200–S202, S215, S222, S226, S232, S234, S239, S249, S250, S253, S257, S258, S261, S261, S263, S266, S268, S270, S275, S276, S287, S290, S292, S297, S302, S305, S308, S314–S317, S324, S327–S329, S337, S347, S352, S361, S364, S371, S378, S381, S395, S396, S408, S425, S436, S438

Fentanyl…………………………S311, S312, S375

FESZ…………………………S245

Fetal…………………………S26, S30, S31, S59, S60, S119, S144, S163, S220, S237, S315, S336, S337, S341, S347, S414, S443

Fetal alcohol spectrum disorder…………………………S341

Fetal development…………………………S10

Fetal programming…………………………S315

Fibromyalgia…………………………S234, S308

First and second generation antipsychotics…………………………S169

First episode…………………………S11, S49, S104, S128, S169, S175, S240, S244, S274, S277, S399

First-generation antipsychotics…………………………S175

FKBP5…………………………S23, S24, S49, S256, S262, S378

Fluoxetine…………………………S79, S83, S119, S201, S205, S206, S252, S265, S265, S297, S301, S307, S314, S346, S425, S425, S431

FMRI…………………………S3–S6, S13, S22–S25, S27, S28, S33, S41, S47–S49, S51, S54, S68, S69, S109–S115, S119, S140, S143–S145, S148, S150, S151, S153, S154, S162–S165, S178, S239, S241, S242, S246, S248, S254, S255, S265–S279, S281, S283–S287, S289–S291, S298, S315, S318, S319, S321, S361–S363, S365, S366, S368, S386, S388, S389, S394–S396, S400, S401–S404, S415, S423

FMRP…………………………S307, S325

Folate…………………………S97, S232, S233

Follow-up…………………………S24, S61, S68, S69, S77, S94, S105, S115, S117, S129, S135, S160, S163, S168, S174, S192, S224, S226, S232, S236, S237, S246, S246, S250, S251, S260, S272, S273, S277, S280, S300, S357, S378, S387, S400–S402, S409, S411, S424, S427

Food intake…………………………S9, S19, S106, S186, S261, S266, S297

Food reward…………………………S8, S9, S41, S48, S188, S215, S266, S372, S373

Foraging…………………………S321

Forced swimming test…………………………S431

FOXO3a…………………………S202, S203

Fragile X syndrome…………………………S259, S307

Free water…………………………S268

Frontal…………………………S21, S27, S32, S34, S41, S46, S58, S77, S83, S91, S110, S112–S114, S119, S126, S127, S129, S148, S150, S151, S155, S158, S165, S205, S210, S227, S236, S238, S241, S243, S254, S255, S264–S266, S268, S270, S271, S274, S275, S280, S281, S283–S285, S288, S290, S297, S307, S310, S320, S336, S342, S345, S361, S362, S382, S385, S387–S389, S396, S398, S401, S403, S411, S433

Frontal lobe…………………………S91, S147, S265, S320, S395, S414, S423

Frontoparietal…………………………S318, S365

Frontostriatal tracts…………………………S152

Functional capacity…………………………S99, , S241, S293

Function…………………………S1, S4–S9, S11, S13, S14–S24, S27, S29–S31, S34, S35, S37, S39, S40, S44, S45, S47–S53, S55, S58–S62, S65, S67–S69, S71, S76, S77, S80, S81, S83–S85, S87, S88, S91, S97, S98, S106, S107, S110, S114–S119, S122, S123, S126, S130, S132, S137–S142, S148, S155, S156, S159–S161, S171, S172, S175–S178, S180, S181, S184, S185, S187–S189, S193–S195, S198, S201, S204, S208–S210, S212, S214, S218–S221, S233, S234, S237, S238, S241, S243, S246, S248, S254, S255, S259, S260, S262, S264, S266–S268, S271, S273–S276, S278, S279, S281–S284, S286–S290, S298, S303–S305, S308–S311, S313, S314, S318, S320, S325, S333–S338, S341, S345, S351, S363, S365–S367, S370, S373–S375, S377, S379, S381, S382, S390, S392, S393, S395–S397, S399, S404, S407, S409, S410, S413, S428, S431, S433, S436, S444, S448

Functional…………………………S2, S3, S5, S6, S10, S15, S20–S24, S27–S29, S32, S33, S36, S37, S40, S45–S49, S51–S54, S56, S60–S64, S68, S69, S76–S78, S83, S84, S86, S90, S93, S95, S97, S99, S105, S110, S112, S117, S119, S125, S126, S129, S131, S132, S134, S143, S146–S148, S150–S153, S155–S157, S170, S183, S185, S188, S192, S193, S195, S198, S199, S202, S206, S209, S213, S218, S221–S224, S231, S232, S234, S238, S240, S242, S243, S246, S250, S253–S255, S257, S261–S263, S266–S268, S270–S274, S277–S279, S281–S283, S286, S289, S290, S292–S294, S303, S305, S307, S310–S312, S318–S321, S333, S336, S338, S339, S341, S355, S357, S361–S363, S373, S374, S377, S379–S381, S384, S386, S388, S391, S395, S398, S399, S401, S402, S405, S409, S415, S418–S420, S423, S424, S432, S437–S440, S442, S447, S448

Functional connectivity…………………………S10, S37, S68, S69, S110, S112, S113, S145, S148–S151, S154, S155, S157, S241, S254, S265, S268, S270, S271, S273, S277, S285, S290, S291, S318, S361, S368, S388, S389, S391, S398, S400, S401, S415

Functional magnetic resonance imaging…………………………S48, S49, S51, S69, S109, S114, S118, S118, S139, S143, S145, S150, S151, S164, S241, S265, S267, S271, S272, S278, S279, S285, S286, S289, S362, S365, S386, S387, S391, S395, S400, S401–S403, S414

Functional neuroimaging…………………………S5, S73, S111, S153, S245, S266, S317, S364, S385

Functional outcome…………………………S34, S40, S117, S174, S242, S418

Functional selectivity…………………………S106, S185, S192, S333, S437

Functioning…………………………S3, S8, S28, S30, S32–S34, S48, S74, S76, S95, S96, S99, S104, S106, S108, S112–S114, S117, S121, S133, S143, S149, S150, S159, S168, S170, S172, S176, S177, S180, S224, S225, S227, S229, S233, S236, S238, S239, S243–S245, S258, S272, S276, S283, S286, S290, S293, S294, S296, S298, S301, S303–S305, S326, S333, S336, S342, S345–S347, S350, S352, S354, S355, S362, S365, S381, S383, S386, S399, S400, S410, S416, S417, S422, S431, S438, S442, S448

G

GABA…………………………S6, S32, S34, S35, S42, S43, S53, S59, S72, S81, S94, S134, S135, S164, S185, S192, S195, S197, S204, S205, S218, S219, S260, S283, S305, S312, S329, S333, S334, S376, S384–S386, S390, S404, S405, S428, S445

GABA B agonist…………………………S289, S404

GABA-A receptor…………………………S42, S135, S329

Gabapentin…………………………S278

GABRA2…………………………S283, S366

GAD67…………………………S42, S71, S72, S203–S205, S219, S222, S384, S385

GAF…………………………S96, S108, S114, S168, S172, S245, S272, S301, S304, S409

Gain…………………………S18, S28, S41, S67, S107, S118, S145, S146, S208, S210, S221, S222, S267, S370, S439, S441

Galanin…………………………S200, S378

Galantamine…………………………S97, S106

Gambling…………………………S13, S28, S215, S284, S297, S298, S309, S342, S368

Gamma…………………………S18, S19, S34, S71, S72, S94, S195–S197, S234, S244, S248, S318, S319, S321, S385, S386, S404

Gamma band activity…………………………S195, S248

Gamma oscillations…………………………S34, S42, S72, S94, S195, S244, S248

Gating…………………………S182, S183, S321, S324, S367, S446

GDNF…………………………S334, S414

Gender…………………………S2, S26, S46, S65, S69, S89, S116, S124, S135–S138, S155, S156, S158, S160, S169, S179, S234, S236, S239, S241, S244, S249, S251, S256, S259, S261, S265, S268, S271, S272, S275, S277, S298, S313, S314, S324, S325, S352, S370, S371, S380, S388, S394, S396, S397, S399, S400, S402, S407, S422, S425, S426

Gene…………………………S3–S5, S8, S10, S14, S15, S17, S21–S24, S26, S27, S29, S31, S37–S40, S42, S43, S45, S46, S48, S49, S51, S52, S54, S55, S61–S65, S71, S73, S77, S80, S82, S84, S85, S87, S89, S91, S92, S122–S128, S130, S132, S133, S135, S146, S180, S181, S185, S198, S199, S207, S208, S210, S211, S213–S216, S235, S238, S239, S242, S245, S247, S253–S265, S268, S283, S284, S300, S301, S307, S312, S327, S330, S331, S335, S337, S342, S372–S381, S383, S385, S393, S397, S405, S445

Gene CRHR1…………………………S125, S262, S378

Gene expression…………………………S3, S8, S18, S19, S23, S26, S27, S30, S31, S46, S50, S55, S60, S61, S71, S78, S85, S90–S92, S123, S128, S135, S138, S200, S202, S204, S208, S210, S213, S214, S219, S253, S254, S257, S263, S265, S293, S333–S338, S341, S342, S372–S374, S378, S385, S409

Gene regulation…………………………S55, S263, S374

Gene therapy…………………………S14

Gene variants…………………………S15, S133, S255, S337, S379, S380

Gene X environment…………………………S5, S132

Gene-environment interaction…………………………S259

General population…………………………S64, S95, S129, S175, S250, S252, S287, S301, S316, S334, S354, S371, S409

Generalized anxiety…………………………S54, S137, S250, S351, S422

Generalized anxiety disorder…………………………S94, S111, S139, S141, S162, S351, S422, S224–S226, S250, S302

Genes…………………………S3, S4, S7, S14–S19, S21–S23, S26–S32, S37, S38, S40, S42, S44, S46–S48, S50–S52, S54, S55, S57, S61, S65, S70, S71, S77, S78, S80, S86, S91, S92, S122, S123, S126, S127, S130–S136, S138, S156, S157, S177, S196, S198, S203, S204, S208, S210, S212, S213, S220, S239, S250, S251, S253–S255, S259–S265, S279, S293, S300, S327, S331, S334, S337, S338, S341, S342, S366, S368, S369, S372–S374, S376, S378, S380, S383, S385, S409, S412, S434, S445

Genetic…………………………S3–S5, S10–S12, S15, S18, S21–S24, S26–S31, S38, S41, S42, S44–S49, S51, S52, S54–S57, S60–S66, S69–S71, S78, S80, S84–S86, S89, S90, S123–S125, S128–S135, S147, S148, S164, S180, S186, S187, S198, S199, S202, S204, S206–S213, S217, S219, S220, S222, S232, S235, S237–S240, S245, S253–S255, S259–S262, S264–S266, S270–S272, S274, S277–S279, S283–S285, S293–S295, S297, S301, S307, S308, S312, S315, S320, S321, S327, S333, S338, S341, S366, S368–S370, S372–S381, S384, S387, S391, S398, S401, S405, S406, S409, S416, S421, S424, S425, S431, S434, S435, S437

Genetic variation…………………………S15, S42, S52, S54, S65, S126, S134, S135, S239, S240, S258, S262, S263, S279, S283, S284, S286, S368, S373, S375–S379, S381, S397

Genetics…………………………S2, S3, S5, S11, S28, S29, S51, S60, S65, S70, S124, S130, S131, S134, S177, S198, S255, S264, S284, S315, S316, S368, S369, S378, S380

Geometry…………………………S275, S276, S399, S411

Geriatric…………………………S230, S231, S236, S397

Gestalt…………………………S248

Glia…………………………S38, S39, S43, S93, S200, S293, S392

Global…………………………S3, S16, S25, S33, S35, S77, S92, S95, S99–S101, S105, S108, S113, S116, S118, S127, S132, S134, S142, S150, S151, S155, S162, S168, S169, S174–S176, S208, S224–S228, S232, S236, S244, S245, S249, S250, S271, S282, S285, S297, S298, S301, S303–S305, S319, S320, S344, S346–S349, S351–S355, S357–S359, S364, S372, S374, S397, S399–S401, S406, S417, S422, S425

GLT-1…………………………S188, S190, S191, S200, S214, S322

Glucose…………………………S53, S92, S102, S120, S121, S162, S169, S173, S174, S176, S208, S256, S257, S267, S270, S302, S354, S392, S413, S415, S416, S445

Glutamate…………………………S6, S16, S17, S29, S34, S39, S46, S50, S58, S59, S84, S88, S122, S133, S135, S136, S139, S140, S185, S188–S191, S193, S200, S209, S214, S215, S229, S230, S259, S278, S295, S304, S305, S312, S319, S320, S322, S325, S326, S333–S336, S338, S376, S381, S382, S384, S392, S430, S438, S440, S441, S445, S446

Glutamine…………………………S34, S278, S312, S381, S445

Glycine…………………………S8, S58, S59, S108, S187, S208, S304, S435, S436

Glycine reuptake inhibitor (GRI)…………………………S58

Glycine reuptake inhibitor (gri)…………………………S435

Glycine uptake inhibitor…………………………S108

Glycopeptide…………………………S312

Goal-directed behavior…………………………S36, S270

Gonadal steroid hormones…………………………S267

GR…………………………S23, S24, S85, S257, S284, S289, S373

Gray matter…………………………S5, S10, S128, S135, S146, S148, S157, S172, S192, S268, S272, S278, S280, S281, S288, S377, S385, S387, S388, S392, S393, S396, S397

Grief…………………………S358, S359, S407

GRM…………………………S382

Growth factor…………………………S22, S66, S90, S125, S202, S208

GSK3…………………………S56, S85, S86, S89, S90, S202, S203, S207, S307, S308

GWAS…………………………S5, S23, S52, S61, S66, S130–S132, S135, S136, S263, S337, S380

Gyrification…………………………S147

H

Habenula…………………………S45, S118, S203, S448

Hair follicle keratinocytes…………………………S218

Hallucinogen…………………………S211

Haloperidol…………………………S42, S103, S173, S184, S187, S274, S305, S335, S359, S382, S384, S436

HAM-A…………………………S111, S140, S143, S224–S226, S351, S422

Hap1…………………………S434

HDAC…………………………S44, S207, S341

HDAC6…………………………S85, S86

Health outcomes…………………………S146, S287, S354, S396

Heart rate variability…………………………S73, S386, S395, S410

Hemoglobin…………………………S251, S388

Heritability…………………………S61, S70, S78, S119, S130–S132, S198, S264, S375–S377

High Resolution fMRI…………………………S281

High risk…………………………S10, S11, S28–S29, S46, S50, S68–S69, S119, S124, S135, S154, S215, S252, S259, S271–S272, S277–S278, S285, S297, S366, S371, S378, S390–S391, S398–S399, S401–S402, S407, S409

High throughput screening…………………………S438

Highly active antiretroviral therapy…………………………S305

Hippocampus…………………………S7, S8, S17, S18, S35, S38, S42, S45, S48, S57, S58, S60, S66, S73, S77, S78, S80, S82–S84, S86–S88, S119, S120, S126, S138, S140, S143, S144, S159, S161, S200, S201, S204, S205, S208, S209, S211, S212, S217, S223, S237, S238, S244, S246, S253–S255, S258, S266, S268, S272, S285, S286, S288, S295, S302, S303, S306, S307, S315, S319, S329, S335, S339, S364, S368, S373, S378, S383, S393, S395, S398, S402, S412, S413, S430, S434, S444

Histamine…………………………S185, S191, S198, S199, S224, S225, S260, S276

Histidine decarboxylase…………………………S198

Histone…………………………S18, S27, S44, S86, S92, S123, S207, S263, S335, S341

Histone phosphorylation…………………………S92

HIV…………………………S288, S305, S393

Hiv infection…………………………S288, S305

HMGB1…………………………S342

Hoarding…………………………S226

Homeostasis…………………………S9, S16, S21, S56, S80, S86, S87, S89, S132, S189, S190, S196, S207, S212, S213, S227, S312, S354, S389, S416, S448

Hormone…………………………S8–S10, S9, S11, S43, S55, S55, S85, S126, S161, S166, S167, S172, S200, S201, S212, S217, S257, S258, S262, S263, S268, S315, S354, S361, S362, S396, S407–S409, S429, S435

Hot flash…………………………S317

HPA…………………………S16, S43, S48, S138, S146, S161, S258, S262, S263, S315, S351, S378, S400, S405, S407, S409

HPA axis…………………………S16, S42, S43, S111, S138, S147, S159, S161, S262, S315, S316, S351, S378, S406, S407, S410, S422

HTR2C…………………………S397, S398

Human…………………………S4, S5, S13–S15, S17, S20, S22–S24, S26–S28, S30, S32, S38, S40, S42, S43, S49, S53, S54, S57–S60, S63, S66, S71, S73, S74, S75, S78, S80–S82, S85, S86, S90, S95, S96, S117–S119, S123, S124, S126, S127, S131, S137–S139, S141, S145, S147, S148, S153, S157, S158, S160, S173, S178–S181, S183, S185, S188, S189, S192, S194–S196, S198, S200, S201, S205, S207, S208, S210, S211, S213, S215, S216, S218, S220, S221, S238, S253, S255, S257–S261, S263, S274, S290, S293, S304, S305, S311–S313, S318, S320, S324, S325, S333, S336–S338, S340–S342, S345, S361, S365–S367, S373, S376, S380–S383, S390, S397, S411, S416, S417, S422, S428, S430, S433, S436, S437

Human brain…………………………S3, S22, S23, S26, S32, S53, S61, S73, S76, S77, S154, S179, S180, S221, S256, S263, S264, S273, S275, S318, S336, S337, S375, S381, S382

Human cytomegalovirus…………………………S336

Human laboratory studies…………………………S428

Human postmortem brain…………………………S57

Humans…………………………S1, S4, S7, S9, S13, S14, S16–S18, S20, S22, S25, S30, S32, S36, S40, S44, S47, S49, S53, S54, S60, S66, S73, S74, S75, S76, S79, S80, S82–S84, S98, S117, S119, S126, S127, S142, S146, S148, S151, S157–S159, S177, S185, S187, S193, S198, S200, S202, S203, S207–S211, S217, S231, S237, S239, S242, S243, S253, S257, S258, S267, S268, S274, S278, S282, S288, S289, S304, S309, S313, S317, S318, S325–S327, S331, S340, S342, S354, S366, S372, S373, S375, S381, S392, S397, S398, S402–S404, S406, S426–S429, S431, S432, S439–S441

Huntington gene…………………………S264

Huntington's disease GSK-3 HDACS transgenic mouse model…………………………S207

Hypopituitarism…………………………S408, S409

Hypothalamus…………………………S7, S9, S10, S19, S55, S111, S119, S158, S193, S203, S233, S234, S255, S258, S262, S266, S308, S315, S317, S337, S400, S405, S432, S447

I

ICSS…………………………S200, S201, S308, S432, S433

IDO…………………………S88

IL-18…………………………S317

Iloperidone…………………………S102, S107, S135

Imaging…………………………S4, S10, S11, S18–S20, S22, S23, S28, S34, S36, S37, S45, S48, S51–S54, S58, S59, S67, S84, S87–S89, S93, S110–S112, S119, S151–S156, S165, S183, S204, S220–S222, S231, S239, S245, S261, S265–S268, S270, S271, S278, S281–S283, S289, S291, S292, S310, S336, S345, S364, S368, S380, S381, S384, S386, S388, S389, S391, S393–S396, S399, S400, S404, S408, S410, S418, S421, S436, S438, S445

Imaging genetics…………………………S22, S239

Imipramine…………………………S85, S206

Immediate early gene…………………………S184

Immune system…………………………S4, S30, S38–S40, S86–S88, S137, S138

Impulse control disorder…………………………S239, S250, S284, S308, S342, S343

Impulsive behavior…………………………S21, S309, S313, S447

Impulsivity…………………………S5, S78, S112, S113, S136, S137, S139, S152, S154–S156, S175, S176, S199, S215, S235, S238, S239, S247, S262, S270, S283, S286, S291, S309, S311, S316, S327, S343, S367, S368, S371, S429, S446

Indo-trinidadians…………………………S177, S178

Induced pluripotent stem cells…………………………S218, S220, S292, S336

Inducible pluripotent stem cells…………………………S292

Infant development…………………………S120, S163

Infection…………………………S30, S31, S71, S137, S213, S218, S242, S288, S303, S305, S336, S392, S448

Inferior frontal gyrus…………………………S109, S150, S241, S248, S272, S387, S399

Inflammation…………………………S37, S39, S43, S49, S52, S86, S88, S137, S269, S310, S348, S354, S414

Inflammatory cytokines…………………………S39, S86, S125, S138, S392, S414

Inhibition…………………………S1, S8, S21, S32, S34, S36, S38, S42–S44, S54, S55, S60, S67, S69, S71, S72, S75, S84–S86, S90, S109, S112, S139, S142, S146, S158, S165, S166, S180, S183, S185, S188, S194, S203, S207, S209, S210, S230, S239, S256, S263, S276, S283, S286, S292, S299, S302, S304, S307, S308, S319, S320, S322, S332, S334, S339, S342, S344, S348, S375, S398, S405, S415, S416, S430, S433–S435, S438, S443, S448

Innate immunity receptor…………………………S164

Inositol monophosphatase…………………………S85, S430

Insomnia…………………………S15, S101, S102, S168, S185, S234, S302, S315, S353, S407

Insula…………………………S47, S48, S58, S108–S110, S112, S119, S140, S144–S146, S151, S156, S178, S238, S242, S265, S266, S270, S277, S283, S284, S288, S290, S319, S361, S364–S366, S368, S386–S389, S393, S396, S399, S401, S403, S447

Insulin…………………………S9, S10, S21, S66, S120, S121, S353

Insulin resistance…………………………S9, S98, S174, S353

Integrins…………………………S87, S260, S261

Interferon…………………………S264, S300, S392

Interleukin-6…………………………S93, S202, S354

Interneurons…………………………S21, S31, S32, S71, S72, S195–S197, S212, S214, S215, S259, S341, S366, S447

Interpeduncular nucleus…………………………S373

Intervention…………………………S24, S43, S44, S64, S71, S83, S97, S106, S107, S117, S119, S122, S129, S135, S143, S162–S165, S169, S215, S231, S238, S240, S242, S251, S253, S264, S272, S287, S298, S307, S352, S356, S359, S366, S370, S371, S380, S394, S401, S415, S419–S421

Intravenous self-administration…………………………S373, S442

In-vivo…………………………S34, S148, S243, S329, S385, S397

Iowa gambling task…………………………S95, S175, S215, S239, S365

IPSC…………………………S42

Ipsc…………………………S218, S293, S336

IQ…………………………S10, S70, S97, S106, S113, S116–S118, S123, S148, S153, S156, S239, S244, S246, S321, S399, S400, S419

Iron deficiency…………………………S251

Irritable bowel syndrome…………………………S364

IRT…………………………S369

K

Kappa opioid receptor…………………………S77, S432, S440, S441

KCNH2…………………………S210

Ketamine…………………………S44, S45, S62, S63, S143, S195, S196, S205, S206, S214, S215, S278, S284, S294, S295, S299, S300, S326, S388, S410, S424

Kinases…………………………S21, S42, S56, S190, S328, S443

Kindling…………………………S1

Kinetics…………………………S42, S72, S171, S287, S340, S436

Knockout…………………………S17, S38, S41, S55–S57, S59, S71, S72, S80, S83–S85, S186, S187, S194, S198, S199, S206, S208, S258, S308, S324, S325, S331, S333, S335, S340, S375, S406

Kynurenic acid…………………………S38, S209

Kynurenine…………………………S38, S209, S300

L

Lamotrigine…………………………S114, S278, S418–S420, S426

Language…………………………S10, S30, S37, S116, S120, S147, S151, S157, S240, S272, S275, S358

L-DOPA…………………………S308

Learned helplessness…………………………S45, S83, S86, S432, S200–S203

Learning…………………………S2, S11, S16–S19, S22, S35, S47, S54, S60, S66, S68, S71, S77, S83, S84, S95, S98, S106, S111, S114, S123, S126, S131, S141, S143, S144, S147, S159, S164, S165, S171, S177, S193, S200, S201, S207, S215–S218, S223, S237, S242, S243, S264, S267, S274–S276, S286, S296, S305, S308, S314, S318–S320, S325, S332, S364, S365, S393, S404, S448

Leptin…………………………S9, S10, S97, S186, S262

Level of response…………………………S177, S326

Levomilnacipran…………………………S344, S345

Lhx6…………………………S384

Life events…………………………S137, S254, S288, S357

Light exposure…………………………S315, S316

Liking…………………………S178, S288, S367, S404, S428

Linkage…………………………S21, S51, S125, S133, S199, S210, S263–S265, S283, S340, S376, S378, S380, S448

Linkage analyses…………………………S264, S265, S377

Lipid…………………………S5, S57, S64, S101, S120, S121, S174, S262, S302, S405, S429, S443

Lisdexamfetamine…………………………S100, S353

Lithium…………………………S65, S66, S85, S86, S90, S92, S114, S125, S128, S139, S146, S172, S181, S207, S208, S221, S249, S256, S263, S298, S300, S302, S303, S308, S332, S349, S354, S359, S391, S392, S400, S412, S418–S421, S423, S424, S430, S440, S441

Local field potentials…………………………S18, S36, S196

Locomotion…………………………S67, S82, S187, S207, S230, S255, S325, S435

Locomotor activity…………………………S6, S34, S50, S58, S75, S111, S123, S152, S184, S185, S190, S191, S193, S200, S209, S214, S217, S258, S304, S310–S312, S316, S329, S333, S335, S375, S412, S432, S435

Locus coeruleus…………………………S56, S75, S80, S110, S440

Long-acting injectable risperidone…………………………S105

Longitudinal…………………………S5, S10, S11, S48, S69, S70, S73, S93, S105, S127, S147, S148, S156, S163, S238, S240, S244, S250, S261, S271–S274, S278, S281, S287, S297, S298, S345, S355, S357, S380, S386, S387, S393, S399, S400, S409, S446

Longitudinal study…………………………S145, S148, S160, S236, S240, S241, S244, S245, S283, S305, S315, S386, S390

LTP…………………………S1, S7, S8, S16, S36, S200, S201, S208, S312, S339, S447

Lupus…………………………S447

Lurasidone…………………………S99, S101, S127, S168–S170, S173, S174, S430, S436

LY379268…………………………S278

Lyme…………………………S447

Lysergic acid diethylamide…………………………S210, S212M

M1 receptors…………………………S237

Macaque…………………………S31, S148, S204, S373

Machine learning…………………………S69, S130, S164

MADRS…………………………S101, S168, S173, S224, S225, S229, S300, S303, S344–S347, S351, S353, S356–S359, S395, S416, S418, S422, S423

Magnetic…………………………S47, S53, S123, S145, S151, S241, S280, S363, S389, S393, S395, S399, S400, S411, S412, S424

Magnetic resonance imaging…………………………S63, S121, S139, S142, S148, S155, S243, S293, S379, S393, S400, S418

Magnetic resonance spectroscopy…………………………S34, S278, S312, S345, S381, S385, S390, S392, S417

Magnetic seizure therapy…………………………S12, S230, S409

Major depression…………………………S2, S15, S18, S28, S39, S42, S43, S45, S48, S49, S54, S69, S80, S87, S89, S93, S110, S118, S119, S125, S128, S146, S172, S200–S203, S205, S218–S221, S229, S251, S270, S272, S300–S302, S304, S328, S347, S359, S365, S386–S388, S390, S391, S395, S400, S413, S424, S432, S443

Major depressive disorder…………………………S3, S38, S44, S45, S68, S69, S88, S89, S91, S93, S94, S115, S118, S119, S124–S126, S136–S138, S172, S201–S205, S222, S226, S229, S230, S250, S263, S296, S301–S304, S315, S343–S348, S350, S351, S353, S354, S356, S357, S386, S388, S389, S393, S394, S397, S398, S402, S413, S414, S417, S418, S422, S422, S431, S448

Maltreatment…………………………S148, S244, S406, S407

Mania…………………………S69, S85, S92, S116, S123, S215, S216, S238, S239, S298, S315, S343, S345, S349, S352–S354, S359, S388, S398–S400, S402, S416, S419, S421, S426

MAO AB knockout…………………………S206

Mao-A…………………………S60, S285, S286, S348, S377, S397

MAOI…………………………S229, S298, S348

Marijuana…………………………S316, S176–S179, S365–S368, S370, S380, S384

Marijuana use…………………………S105, S176–S179, S301, S367

Mass spectrometry…………………………S166, S167, S443

Maternal…………………………S10, S17, S30, S55, S59, S60, S73, S74, S102, S109, S112, S118–S120, S145, S151, S159, S237, S238, S250, S251, S254, S258, S261, S295, S315, S336, S337, S361, S362, S377, S406

MC4R…………………………S65, S132

MDD…………………………S3, S44, S45, S69, S87–S89, S91–S94, S110, S117–S120, S124, S126, S138, S159, S201, S202, S204, S205, S222, S229, S231, S258, S263, S296, S301–S303, S315, S343, S344, S346–S348, S351, S353, S354, S356, S357, S383, S389–S391, S394–S396, S398, S400, S401, S414, S417, S418, S422–S424, S432, S444

MDL100907…………………………S282

MDMA…………………………S282, S342, S427

Medial prefrontal cortex…………………………S18, S19, S34–S36, S62, S63, S82, S110, S113, S140, S144, S154, S182, S203, S211, S213, S289, S311, S319, S320, S327, S362, S364, S366, S372, S374, S388, S395, S412, S435, S442, S446

Medial visceromotor network…………………………S395, S396

Medication…………………………S3, S7, S12, S13, S35, S38, S65, S87, S90, S97, S99, S102–S106, S118, S122, S133, S135, S136, S151, S153, S160, S161, S164, S167–S169, S173–S175, S179–S181, S189, S195, S221, S225, S226, S228, S232, S233, S235, S245, S247, S249, S251, S266, S272–S274, S277, S279, S285, S286, S290, S292, S297, S301, S305, S344, S347, S349, S351, S352, S354, S357, S360, S368, S371, S383, S387, S389, S390, S392, S397, S400, S405, S420, S422–S428, S434, S442

Meditation…………………………S264

Medium spiny neurons…………………………S67

MEG…………………………S5, S32, S240, S247, S318, S321

Meg…………………………S365, S386

Melatonin receptors…………………………S217

Memory…………………………S1–S4, S6, S16–S19, S22, S33, S35, S36, S41, S44, S49, S63, S66, S67, S71, S76, S77, S80, S82, S84, S85, S98, S99, S104, S106, S107, S114, S116–S119, S123, S131, S134, S141, S143, S159, S171, S172, S177, S182, S184, S185, S200, S207, S209, S211, S217, S218, S223, S235–S237, S245, S253–S256, S264, S270, S272, S274–S276, S278, S285, S305, S308, S309, S313, S316, S318, S320, S339, S350, S364, S365, S393, S399, S402, S404–S406, S408, S411, S412, S415, S423, S437

Menopause…………………………S93, S200, S268, S317, S408

Mesolimbic…………………………S7, S28, S92, S107, S178, S179, S209, S322, S323, S333, S334, S363, S378, S404, S444, S449

Meta-analysis…………………………S57, S104, S115, S132, S147, S150, S151, S168, S170, S176, S231, S242, S356, S359

Metabolic effects…………………………S121, S162, S174, S439

Metabolic syndrome…………………………S24, S97, S98, S132, S175, S302, S352, S354, S425

Metabolism…………………………S21, S39, S48, S53, S64, S80, S88, S92, S97, S98, S120, S121, S161, S162, S180–S182, S208, S232, S233, S241, S242, S256, S257, S262, S267, S270, S278, S289, S301, S309, S331, S345, S386, S392, S399, S408, S413, S415, S435, S442, S448

Metabolism FKBP5 gene…………………………S256, S262

Metabolomics…………………………S24

Metacognitive…………………………S246

Metformin…………………………S174

Methadone…………………………S427, S428

Methamphetamine…………………………S13, S14, S126, S180, S189, S190, S217, S222, S289, S291, S319, S324, S325, S339, S340, S342, S375, S377, S380, S403, S405, S441, S442

Methodology…………………………S12, S23, S26, S40, S100, S112, S120, S167, S220, S236, S255, S360, S416, S420

Methylation…………………………S5, S18, S22–S24, S26, S27, S48, S73, S92, S123, S130, S254, S258, S297, S304, S307, S327, S356, S372, S417, S420

Methylphenidate…………………………S19, S67, S75, S83, S113, S127, S153, S230, S286, S291

Mglu5…………………………S66

Mglur2…………………………S335, S382

Mglur4…………………………S305, S306, S382

Mglurs…………………………S193, S326, S382

Mibampator…………………………S227

Mice…………………………S2, S8, S9, S14–S16, S18, S21, S22, S30, S32, S34, S38–S43, S45, S54–S60, S67, S71, S72, S75–S89, S92, S94, S111, S123, S126, S127, S161, S182–S189, S191, S194–S197, S198–S200, S202–S219, S222, S223, S253, S258, S278, S305, S306, S308, S311–S313, S324, S325, S327, S329–S333, S335, S337, S338, S340, S342, S373–S375, S393, S412, S413, S430–S435, S437, S441, S443–S445

Microarrays…………………………S57, S78, S85, S91, S258

Microdialysis…………………………S6, S20, S47, S58, S81, S182, S185, S188, S191, S198, S209, S307, S310, S311, S323, S436

Microglia…………………………S39, S40, S64, S86, S192, S336

Microrna…………………………S77, S208, S293, S338

Midbrain…………………………S9, S20, S28, S35, S47, S78, S85, S87, S88, S119, S198, S238, S266, S268, S286, S291, S318, S319, S364, S380, S397, S409, S441

Migration…………………………S31, S32, S49, S89, S208, S222, S260, S341

Mild cognitive impairment…………………………S52, S236

Mindfulness…………………………S162, S163

Minority…………………………S36, S121, S300, S355, S370

Mirna…………………………S293, S338, S339, S374

Mismatch negativity…………………………S33, S34, S134, S169

Mitochondria…………………………S220, S221

Mixed state…………………………S420

MK-801…………………………S8, S182, S183, S214, S304

Modafinil…………………………S66, S67, S177

Model…………………………S3, S4, S6, S9, S13–S18, S21, S22, S24–S26, S30, S31, S33, S34, S39, S40, S43–S45, S47, S48, S50, S53–S56, S58, S60, S61, S66, S70, S72, S73, S76–S78, S80, S81, S83–S85, S87–S90, S92, S96, S97, S99, S101, S104–S106, S111, S113, S116, S117, S127, S130, S133–S135, S143–S146, S148, S151, S153, S156–S158, S164, S168, S174, S178, S179, S181, S184–S189, S191, S192, S195, S196, S198–S216, S218, S222–S225, S227, S229, S230, S234, S235, S237–S239, S243, S246, S252, S253, S256, S259, S263, S265, S266, S270, S271, S276–S279, S282, S294, S296, S298, S304–S308, S311, S315, S317, S320, S322, S324–S327, S330, S332, S334, S336, S339–S341, S344, S345, S354, S357, S364–S366, S369, S372, S373, S376, S377, S383–S386, S389, S391, S392, S398, S399, S401, S403, S404, S409, S411, S425, S427, S429–S433, S436–S439, S441, S444, S448

Moderators…………………………S3, S104, S355, S379, S380, S395

Monkey…………………………S13, S48, S53, S146, S148, S149, S204, S219, S231, S318, S340, S409, S436

Monoamine Oxidase a…………………………S285, S298, S397

Monoamines…………………………S173, S182, S206, S218, S319

Monozygotic twins…………………………S148, S256

Mood…………………………S15, S16, S19, S38, S44, S45, S48, S49, S54, S55, S57, S68–S70, S73, S82, S85–S87, S90, S92, S114, S119, S125, S132, S137, S142, S153, S161–S163, S176, S200, S224, S225, S239, S251, S252, S259, S265, S282, S285, S288, S290, S298, S315, S317, S318, S343, S347, S349, S350, S354, S355, S357, S359, S370, S372, S379, S388, S390, S393, S396, S399, S400, S404, S417–S422, S426, S427, S430–S432, S448

Mood disorders…………………………S15, S21, S22, S38, S55, S57, S59, S61, S67–S70, S80, S86, S89, S90, S92, S93, S110, S125, S126, S128, S135, S138, S163, S200, S201, S204, S205, S219, S221, S238, S253, S302, S314, S315, S336, S357, S376, S383, S390, S393, S397, S398, S448

Morphine…………………………S36, S50, S81, S167, S311, S312, S331, S332

Motion…………………………S68, S149, S153, S154, S201, S248, S268, S271, S289, S391, S402, S413

Motivation…………………………S7, S9, S19, S28, S36, S41, S112, S118, S119, S158, S190, S193, S194, S199, S200, S205, S238, S239, S241, S266, S267, S339, S393, S403, S404, S440

Motor…………………………S6, S31, S50, S55, S75, S112–S114, S118, S120, S130, S134, S137, S154, S156, S165, S166, S178, S184, S190, S200, S203, S207, S227, S232, S239, S240, S242, S271, S284, S290–S292, S305, S306, S308, S311, S319, S321, S324, S333, S343, S361, S367, S386, S391, S397, S410, S411, S416, S432

Mouse…………………………S5, S8, S13, S15, S17, S18, S22, S29–S31, S34, S39, S40, S43–S46, S54–S56, S60, S71, S72, S75, S76, S81, S83–S87, S92, S127, S183, S188, S194, S196, S199, S200, S202, S205–S208, S211, S212, S214–S217, S253, S306–S308, S311, S327, S329, S340, S342, S373, S374, S393, S430, S437, S443

Movement…………………………S44, S69, S80, S95, S99, S156, S169, S174, S212, S216, S268, S281, S311, S319, S385, S386, S408, S431, S447

Movement disorder…………………………S95, S96, S169

mPFC…………………………S18, S19, S34–S36, S60, S62, S63, S71, S74, S82, S110, S154, S165, S182, S211–S213, S311, S315, S327, S329, S362, S364, S366, S372, S374, S433, S436, S446

MRI…………………………S3–S6, S10, S23, S28, S33, S36, S41, S48, S49, S53, S63, S68, S69, S91, S119, S121, S139, S141, S142, S144, S146, S148–S151, S154, S156, S158, S165, S174, S243, S244, S264, S266, S268, S269, S271, S272, S274, S276, S277, S280–S283, S286, S293, S302, S303, S318, S320, S363, S379, S381, S385, S387, S390, S394–S396, S398, S402, S413, S418

MRS…………………………S5, S10, S25, S34, S35, S136, S277, S278, S385, S390, S391, S417

MST…………………………S230, S231, S410

mTBI…………………………S267, S268, S408, S408

MTHFR…………………………S97, S98, S232, S233, S245

Mu…………………………S38, S126, S311, S375

Muscarinic…………………………S62, S67, S181, S236, S422

Myelin…………………………S166, S192, S243, S269, S278, S333, S336

Myelination…………………………S6, S147, S157, S278, S336

Myosin…………………………S339

N

N170…………………………S248

N250…………………………S248

NAA…………………………S139, S140, S277–S278

N-acetylaspartate…………………………S139, S277

Naltrexone…………………………S114, S178, S180, S181, S186, S235, S301, S342, S367, S426–S427, S438

Narp…………………………S412, S413

NDEL1…………………………S219

NDST3…………………………S132

Near-miss…………………………S309, S310

Negative symptoms…………………………S20, S33, S34, S40, S41, S72, S97–S99, S105–S108, S135, S171, S176, S185, S187, S195, S221, S232, S245, S368, S369, S440

Negative Symptoms of Schizophrenia…………………………S100, S108, S171, S183, S213, S233

Neopterin…………………………S300

Network…………………………S2, S10, S12, S15, S22, S23, S24, S28, S32, S44, S45, S51–S53, S61, S69, S72, S85, S88, S110, S112, S113, S115, S119, S120, S123, S130, S136, S143–S146, S148–S151, S154–S156, S161, S175, S195, S196, S203, S208, S213, S218, S221, S236, S241, S245, S247, S255, S259, S260, S270–S273, S275, S276, S280, S282, S284, S285, S290, S294, S299, S310, S318–S320, S335, S337, S338, S341, S354, S356, S361–S363, S365–S368, S374, S376, S381, S386, S387, S389, S391, S395–S397, S399, S409, S412, S416, S425, S447

Neurogenesis…………………………S16, S38, S39, S67, S85, S87, S89, S161, S339, S341, S342, S374, S412, S434

Network analysis…………………………S46, S61, S274, S282, S396, S397

Neural stem cell transplantation…………………………S341

Neuregulin…………………………S208, S278, S374

Neuroactive steroids…………………………S390

Neuroanatomy…………………………S6, S148, S394, S400

Neurocognition…………………………S40, S118, S147, S170, S239, S294, S305

Neurodegeneration…………………………S207, S257, S305, S342, S393

Neurodevelopment…………………………S26, S42, S78, S135, S145, S147–S149, S209, S213, S219, S240, S261, S279, S320, S336, S337, S394

Neurodevelopmental…………………………S5, S10, S11, S21, S27, S29–S32, S46, S49, S50, S59, S70, S84, S123, S128, S129, S148, S156, S187, S198, S213, S218, S237, S238, S240, S259, S260, S275, S279, S320, S327, S336, S337

Neuroeconomics…………………………S366

Neurofeedback…………………………S164, S165

Neurogenesis…………………………S16, S38, S39, S67, S85, S87, S89, S161, S339, S341, S342, S374, S412, S413, S435

Neuroimaging…………………………S4–S6, S10, S15, S21, S23, S29, S37, S41, S48, S49, S51–S53, S69, S73, S91, S92, S108–S110, S112–S114, S119, S129, S142, S148, S152, S155, S158, S162, S163, S192, S203, S267, S268, S274, S278, S280, S289, S295, S318, S381, S384, S389, S391–S394, S398

Neuroinflammation…………………………S268, S279, S342

Neuromodulation…………………………S165, S386

Neuropeptide S…………………………S193

Neuropeptide Y…………………………S32, S57, S132, S172, S204, S212, S262, S378

Neuropeptides…………………………S9, S11, S72, S193, S212, S216, S361, S433

Neurophysiology…………………………S6, S231, S314, S389, S410

Neuropsychiatric disorders…………………………S10, S12, S25, S26, S40, S46, S56, S60, S66, S67, S70, S71, S83, S133, S138, S139, S143, S145, S195, S198, S207, S212, S216–S218, S228, S238, S255, S276, S284, S292, S294, S319, S416, S438

Neuropsychiatric symptoms…………………………S227, S281, S409, S448

Neuropsychology…………………………S4, S5, S11, S95, S96, S107, S112, S113, S116, S118, S131, S134, S152, S171, S227, S237, S238, S247, S265, S272, S274, S292, S293, S305, S351, S386, S409, S415

Neuroregulin…………………………S7, S208, S279, S374, S375

Neuropsychological assessment…………………………S96, S386

Neurosteroid…………………………S81, S306, S307, S341

Neurotensin…………………………S190

Neurotrophins…………………………S86, S202, S338

Next generation sequencing…………………………S26, S46, S61, S123, S125, S131, S213, S222, S263, S372, S374

NF-kB…………………………S19

NGF…………………………S124

Nicotine…………………………S6, S9, S13, S50, S51, S67, S95, S98, S151, S164–S166, S179, S189, S191, S221, S235, S237, S243, S277, S284, S285, S287, S289, S290, S326, S332–S334, S368, S372–S375, S378–S381, S403, S404, S427, S439

Nicotine dependence…………………………S13, S50, S165, S189, S277, S284, S285, S291, S332, S333, S373–S375, S378–S380, S428

Nicotine withdrawal…………………………S179, S180, S243, S368, S373–S375, S405

Nicotine-seeking…………………………S326, S332

Nicotinic…………………………S67, S97, S98, S106, S107, S171, S179, S182, S183, S185, S191, S199, S326, S368, S372, S373, S378–S380, S403

Nicotinic acetylcholine receptor…………………………S41, S97, S106, S183, S372, S373, S375

Nicotinic receptors…………………………S179, S191, S209

NK1 antagonist: Aprepitant::…………………………S427

NMDA…………………………S7, S8, S16, S34, S35, S44, S45, S58, S71, S72, S187, S189, S190, S194, S205, S209, S283, S295, S299, S304, S326, S329, S338, S382, S435, S438

NMDA antagonist…………………………S62, S190, S214, S215, S295, S304

NMDA receptor…………………………S7, S8, S16, S17, S34, S45, S58, S62, S72, S84, S88, S187, S189, S195, S196, S208, S283, S284, S305, S329, S381, S382, S384, S435, S437

NMDA receptor antagonist…………………………S44, S58, S195, S196, S205, S283

nNOS…………………………S219

Nociceptin…………………………S234

Nonhuman primates…………………………S148, S231, S326, S439

Nonmedical prescription opioid use…………………………S370

Noradrenaline…………………………S79, S182, S224, S225

Noradrenergic…………………………S6, S7, S76, S80, S81, S83, S111, S143, S180, S284, S309, S441

Norepinephrine…………………………S6, S7, S21, S60, S75–S77, S80, S81, S83, S153, S180, S187, S194, S205, S276, S286, S302, S310, S328, S331, S332, S339, S340, S344, S346, S374, S422, S431, S441, S442, S448

Nosology…………………………S2

Novel object recognition…………………………S72, S152, S182, S209, S210, S431, S437

Novel P3…………………………S245

Novelty seeking…………………………S126, S127, S327, S377

NPY…………………………S132, S133, S172, S173, S204, S213, S261, S378

NRXN1…………………………S29, S260, S337

Nucleus accumbens…………………………S6, S13, S19, S36, S47, S49, S56, S67, S73, S78, S79, S82, S84, S90, S107, S112, S119, S126, S145, S146, S166, S174, S179, S184, S185, S188, S190, S191, S202–S204, S209, S214, S238, S242, S254, S258, S265–S267, S287, S289, S291, S292, S311, S312, S317, S322, S325, S328, S329, S331, S333–S335, S337, S338, S340, S361, S363, S380, S382, S391, S397, S404, S412, S433, S442, S446

NVHL…………………………S56, S211

O

Obesity…………………………S95, S121, S137, S158, S159, S237, S251, S261, S262, S266, S267, S291, S354, S416, S444, S8–S10, S12, S39, S47, S52

Obsessive compulsive disorder…………………………S1, S28, S40, S54, S75, S79, S108, S136, S144, S216, S226, S229, S249, S255, S282, S294, S321

Occupancy…………………………S13, S24, S58, S59, S173, S174, S179, S180, S183, S206, S435, S436, S438

OCD…………………………S40, S75, S76, S79, S108, S109, S136, S141, S144, S145, S226, S229, S249, S250, S255, S294, S295

Offspring…………………………S30, S31, S68, S69, S79, S102, S120, S132, S145, S151, S163, S202, S209, S213, S222, S237, S238, S250, S251, S261, S315, S320, S327, S336, S337, S361, S389, S391

Olanzapine…………………………S22, S58, S65, S105, S107, S120, S121, S127, S128, S133, S170, S173, S175, S176, S184, S186, S187, S205, S275, S352, S384, S424, S434, S438

Oleoylethanolamide…………………………S383

Olfaction…………………………S440

Oligodendrocyte…………………………S333, S336

Omega-3 fatty acids…………………………S413

Open field…………………………S38, S75, S80, S83, S126, S127, S164, S187, S200, S209, S215, S333, S335, S416, S434, S441

Operant…………………………S79, S189–S191, S193, S211, S313, S323, S324, S325, S339, S363, S429

Opioid…………………………S7, S36, S47, S166, S167, S178, S186, S235, S311, S312, S317, S318, S367, S370, S371, S375, S376, S392, S393, S427, S428, S439, S441, S443

Opioid dependence…………………………S367, S427

Opioid withdrawal…………………………S427, S428

Opioids…………………………S36, S37, S167, S206, S310, S367, S370, S371, S375, S376, S392, S393

OPRM1…………………………S180, S181, S235, S254, S375, S376

Optogenetics…………………………S45, S92, S196, S444

Orbitofrontal…………………………S35, S79, S83, S152, S154, S158, S241, S315, S319, S364, S365, S403

Orbitofrontal cortex…………………………S27, S35, S75, S79, S82, S91, S126, S154, S155, S266, S276, S290, S377, S388, S405

Orexin…………………………S9, S194, S233, S234, S317, S433, S434

Organic cation transporters…………………………S430

Oscillation…………………………S32, S71, S72, S94, S157, S195, S196, S248, S271, S385, S400, S448

Outcome…………………………S2, S3, S7, S11, S12, S20, S28, S34, S35, S43, S52, S58, S73, S75, S84, S94, S97–S100, S104, S105, S106, S108, S113, S115, S120, S121, S122, S133–S135, S140, S146, S148, S151, S161, S162–S164, S167, S168, S170, S172, S175, S176, S178, S179, S181, S186, S209, S210, S223, S226, S231, S233, S235, S238, S241, S242, S251, S262, S267, S275, S278, S299, S303, S309, S314, S327, S336, S342–S345, S348, S350, S351–S355, S357, S358–S361, S367, S369, S378, S381, S394, S395, S398, S399, S400, S405, S407, S410, S414, S415, S417, S419–S421, S424, S426–S428, S430

Oxcarbazepine…………………………S359

Oxidation…………………………S57, S445

Oxidative stress…………………………S57, S93, S214, S342, S345, S374, S435, S444, S445

Oxygen…………………………S238, S289, S342, S345, S395, S400, S415, S424, S444, S445

Oxytocin…………………………S72, S73, S96, S160, S161, S166, S255, S361, S406, S408, S421, S422, S428, S439, S448

P

P2…………………………S245, S295

P3b…………………………S245

PACAP…………………………S23, S257, S258

Pain…………………………S36, S37, S124, S125, S137, S159, S167, S227, S235, S297, S310, S311, S317, S318, S345, S350, S359, S364, S375, S386, S392, S393, S397, S432, S433, S448

Paliperidone extended-release…………………………S102

Palmitoylethanolamide…………………………S383

PANSS…………………………S49, S95–S97, S99–S103, S106–S108, S133, S135, S136, S169–S175, S232, S233, S246, S272, S274, S277, S280, S294, S415, S424

Parent training…………………………S228

Parental…………………………S55, S78, S102, S113, S148, S158, S159, S252, S258, S265, S277, S362, S407

Parkinsonism…………………………S102, S414

Parkinson's disease…………………………S25, S26, S70, S94, S116, S117, S286, S292, S297, S305, S308, S319, S343, S414

Paroxetine…………………………S120, S225, S226, S346, S351, S434, S435

Partial agonist…………………………S171, S179, S181–S183, S185, S186, S192, S224, S225, S303, S357, S368, S375, S381, S382, S437

Partial deletion…………………………S156

Parvalbumin…………………………S21, S32, S42, S72, S94, S196, S204, S205, S212, S219, S385

Paternal age…………………………S70, S102, S250

Pathological gambling…………………………S28, S297, S309, S342

Pathology…………………………S5, S8, S17, S31, S40, S42–S44, S59, S66, S81, S88, S92, S116, S123, S153, S154, S161, S205, S207, S209, S218, S219, S227, S277, S292, S308, S309, S337, S342, S363, S381, S390, S393, S408, S432, S446

Pathway…………………………S7, S16–S19, S22, S23, S31, S38, S39, S44–S46, S48, S52, S56, S57, S59, S61, S62, S64, S65, S88–S91, S110, S130, S186, S187, S204, S208, S214, S216, S217, S221–S223, S230, S234, S258–S261, S277, S283, S305, S328, S333, S334, S337, S339, S340, S363, S372, S374, S375, S393, S401, S434, S435, S443, S446

PDE…………………………S223, S337, S338, S432

P-CREB…………………………S328, S335

Pediatric…………………………S30, S60, S65, S83, S121, S123, S141, S147, S151, S163, S265, S296, S311, S349, S350, S387, S388, S391, S394, S400

Pediatric bipolar…………………………S5, S152

Pediatric bipolar disorder…………………………S5, S112, S252, S253, S349

Pediatrics…………………………S77, S137, S240

Peptide…………………………S29, S32, S43, S166, S185, S191, S212, S258, S266, S311, S422, S430, S432, S433, S441, S448

Perceptual integration…………………………S32

Perinatal…………………………S214, S215, S390

Peritraumatic dissociation…………………………S142

P-ERK…………………………S186, S328

Personality…………………………S39, S130, S139, S238, S262, S263, S270, S288, S296, S315, S371, S372, S375–S377, S379, S386, S429, S430

Pervasive developmental disorders…………………………S228

PET…………………………S9, S13, S19, S20, S25, S48, S58, S59, S63, S142, S154, S155, S161, S162, S174, S179, S180, S198, S221, S265, S266, S270, S271, S276, S280, S282, S285, S287–S292, S317, S318, S363, S379, S381, S384, S386, S393, S397, S402–S404, S413, S436, S437, S447

PET neuroimaging…………………………S317

PFC…………………………S6, S18, S21, S27, S36, S41, S42, S48, S61–S63, S72, S82, S110, S120, S138, S140, S147, S185, S187, S188, S193, S194, S200, S209, S211, S213, S219, S238, S270, S289, S295, S325, S328, S333, S337, S366, S368, S383–S385, S388, S399, S443, S444

Ph…………………………S26, S61, S62, S72, S82, S87, S89, S182, S193, S221, S233, S234, S310, S345, S355, S382, S384

Pharmacogenetics…………………………S64, S122, S180, S181, S320

Pharmacokinetics…………………………S14, S206, S404, S442

Pharmacotherapy…………………………S7, S12, S14, S79, S84, S163, S178, S186, S189, S212, S218, S226, S294, S297, S310, S311, S322, S352, S354, S412, S426, S428, S430

Phase 2B clinical trial…………………………S133

Phencyclidine…………………………S58, S182, S187, S188, S212, S431, S437

Phenomenology…………………………S198, S265, S314

Phenotype…………………………S13, S17, S21, S26, S27, S29, S52, S59, S64–S66, S71, S73, S77, S78, S81, S82, S85, S90, S92, S123, S125, S130, S131, S161, S198, S201–S205, S207, S213, S214, S238, S253, S256, S266, S279, S312, S329, S330, S368, S369, S378, S383, S387, S432, S443, S444, S448

PHNO…………………………S13, S158, S198, S268, S269

Phosphodiesterase…………………………S223, S322, S433

Phronotype…………………………S394

Physical activity…………………………S97, S98, S251, S339

Physiology…………………………S18, S23, S42, S53, S55, S59, S60, S67, S71, S172, S182, S187, S197, S200, S201, S217, S279, S312, S321, S324, S405, S407, S439, S441, S447

Pioglitazone…………………………S354

PKA…………………………S221, S328, S338, S340

Place conditioning…………………………S50, S440

Placebo…………………………S7, S12, S14, S19, S37, S44, S49, S62, S94–S104, S106–S108, S113, S118, S133, S147, S159, S161, S162, S169–S171, S173, S177–S181, S186, S195, S224–S227, S229–S235, S237, S276, S283, S284, S286, S287, S290, S291, S296, S297, S299–S301, S303, S309, S317, S318, S342–S346, S348–S353, S356–S359, S364, S365, S368, S375, S379, S382, S385, S404, S409, S417–S424, S426–S429, S436, S440

Placebo-controlled…………………………S24, S62, S95, S100, S103, S104, S107, S108, S127, S128, S161, S162, S168, S173, S180, S342, S344–S346, S348–S351, S353, S354, S356, S357, S360, S368, S378, S380, S417, S421, S422, S425–S428, S224–S227, S229, S230, S233, S234, S276, S283, S299, S301, S303

Plasticity…………………………S16–S19, S35, S38, S40, S55, S56, S59, S63, S66, S76, S81, S85, S89, S135, S139, S146, S172, S217, S223, S248, S325, S334, S338, S339, S341, S374, S391, S410, S434, S440, S446–S448

Play behavior…………………………S151, S443, S448

PMDD…………………………S127

PMS…………………………S127

Polymorphism…………………………S21, S22, S26, S29, S38, S46, S52, S71, S80, S125–S127, S135, S149, S180, S209, S238, S239, S247, S253, S257, S258, S279, S284, S297, S301, S380, S383

Polypharmacy…………………………S168, S352

Polysomnography…………………………S196, S314

Positive allosteric modulator…………………………S58, S81, S97, S106, S227, S230, S305

Positron Emission Tomography…………………………S20, S48, S63, S142, S158, S161, S179, S198, S221, S256, S265–S268, S280, S282, S285, S291, S319, S379, S386, S392, S393, S397, S402, S403, S413, S438

Post traumatic stress disorder…………………………S80

Posterior cingulate…………………………S4, S51, S110, S119, S140, S145, S150, S154, S246, S265, S267, S268, S271, S284, S285, S318, S319, S362, S364, S365, S368, S408

Postmenopausal…………………………S93, S317, S408

Postmortem…………………………S8, S27, S34, S35, S42, S53, S57, S61, S83, S87, S89–S93, S132, S135, S138, S157, S184, S187, S202, S204, S205, S214, S218, S220, S221, S240, S257, S333, S337, S378, S381, S382, S384, S385

Postmortem brain…………………………S17, S86, S91, S92, S137, S138, S210, S221, S222, S432, S434

Postnatal…………………………S10, S17, S21, S30, S32, S50, S59, S60, S78, S83, S84, S120, S123, S145, S148, S151, S163, S183, S188, S194, S209, S213–S215, S219, S220, S222, S253, S295, S316, S337, S431, S443, S447

Postpartum…………………………S148, S200, S347, S390, S397

Postpartum depression…………………………S390, S397

Posttraumatic stress…………………………S17, S256, S407

Posttraumatic stress disorder…………………………S1, S7, S24, S76, S78, S111, S140, S142, S143, S257, S267, S296, S313, S314

Postural sway…………………………S292

Power spectral analysis…………………………S196, S234, S314

PPI…………………………S34, S69, S72, S75, S76, S110, S131, S134, S169, S170, S184, S198, S199, S213, S214, S240, S254, S255, S259, S264, S265, S334, S448

Prader-Willi syndrome…………………………S266, S267

Pramipexole…………………………S184, S308, S309

Prazosin…………………………S6, S7, S332

Pre-mild cognitive impairment…………………………S236

Preclinical…………………………S7, S13, S24, S25, S36, S37, S40, S41, S43, S59, S66, S89, S98, S107, S126, S182, S189, S191, S192, S201, S230, S258, S268, S284, S287, S297, S306, S311, S312, S317, S324, S325, S342, S379, S384, S397, S402, S405, S411, S427, S432, S435, S436, S438

Prediction…………………………S7, S11, S27, S31, S35, S47, S91, S126, S130, S154, S287, S310, S327, S365, S381

Prefrontal…………………………S3, S5, S7, S15, S16, S20–S23, S26–S28, S32, S34–S36, S42, S44, S45, S50, S53–S55, S57, S61–S63, S68, S69, S72, S77, S82–S84, S89, S109, S110, S112, S114, S115, S119, S123, S135, S138, S140, S142, S145, S147, S148, S150, S152, S154, S157, S165, S169, S182, S184, S185, S187, S192–S196, S200, S203, S204, S209, S213, S215, S219, S220, S223, S236, S238, S243, S245, S247, S253, S255, S266, S269, S270, S273–S277, S279, S281, S282, S285, S286, S290, S295, S297, S298, S307, S311, S313, S315, S318–S321, S325, S327–S329, S333, S337, S340, S365, S366, S381, S384–S388, S391, S396–S400, S402, S403, S411, S436, S440, S445, S448

Pregnancy…………………………S10, S59, S60, S120, S145, S151, S163, S237, S238, S251, S261, S315, S327, S347, S390

Pregnenolone…………………………S306, S307

Prelimbic…………………………S35, S50, S54, S83, S84, S194, S440

Pre-mild cognitive impairment…………………………S236

Prenatal…………………………S26, S27, S70, S120, S145, S148, S151, S152, S220, S222, S251, S315, S327, S336

Prenatal cortisol…………………………S145

Preparation…………………………S26, S167, S247, S271, S272, S394, S398, S407, S408, S430, S445

Pre-pregnancy BMI…………………………S238

Prepulse inhibition…………………………S21, S34, S72, S75, S76, S98, S131, S134, S169, S184, S198, S213, S214, S240, S243, S264, S334, S434, S446

Prevalence…………………………S9, S18, S30, S55, S56, S75, S83, S116, S122, S129, S150, S155, S158, S175, S193, S211, S250–S252, S255, S288, S309, S315, S343, S360, S370, S371, S378, S397, S408, S409, S416, S420, S425, S428

Prevention…………………………S11, S18, S24, S38, S63, S64, S69, S78, S86, S112, S129, S139, S144–S146, S161, S162, S191, S230, S236, S240, S256, S257, S261–S264, S296, S305, S317, S347, S357, S371, S380, S392, S394, S407, S426, S437, S442

Primary insomnia…………………………S233, S234

Primates…………………………S13, S48, S53, S83, S87, S145, S148, S318, S342, S364, S373, S376, S415

Prison…………………………S262

Prodromal…………………………S10, S129, S226, S227, S240, S241, S245, S271, S272, S383

Prodrome…………………………S100, S128, S241, S242

Prodrug…………………………S133, S199, S200, S320

Prognostic grouping…………………………S419

Programming…………………………S315, S336

Progressive change…………………………S10, S281

Propentofylline…………………………S322

Proteomics…………………………S24

Psychiatry…………………………S1, S2, S5, S10, S25, S47–S49, S53, S65, S67, S76, S77, S85, S87, S93, S104, S113, S115, S126, S129, S132–S134, S136, S137, S141–S143, S146, S152, S154, S156, S159, S160, S162, S163, S165, S166, S172, S176, S191, S197, S199, S206, S214, S216, S218, S219, S221, S225, S226, S229, S230, S236, S240–S243, S248, S249, S251, S255, S258, S262, S265, S266, S270, S276, S277, S280, S282–S285, S290, S295, S296, S298, S299, S302, S303, S312, S317, S327, S338, S341, S342, S344, S349, S355, S356, S359, S365, S375, S377, S378, S390, S391, S394, S396–S398, S400, S402, S410, S417–S421, S427, S431, S434, S444

Psychometrics…………………………S417

Psychomotor…………………………S118, S123, S243, S320, S420, S442

Psychopathology…………………………S5, S18, S24, S49, S56, S78, S81, S95, S105, S106, S109, S110, S112, S119, S121, S126, S129, S134–S136, S141, S148, S162, S168, S172, S176, S201, S204, S238, S244, S246, S249, S250, S257, S258, S265, S266, S272, S280, S294, S383, S384, S407

Psychophysiology…………………………S141, S406

Psychosis…………………………S10, S11, S17, S41, S49, S94, S95, S98, S100, S101, S103, S104, S106, S117, S129, S130, S135, S172, S208, S210, S212, S221, S240, S241, S245–S248, S271, S272, S275, S278, S281, S294, S337, S338, S368, S369, S383, S394, S396, S409, S412, S437, S442

Psychostimulant…………………………S13, S75, S180, S327, S339, S340, S342, S375, S441, S442

Psychotherapy…………………………S23, S24, S76, S110, S136, S159, S162, S166, S172, S257, S265, S402

Psychotic…………………………S2, S3, S11, S17, S25, S49, S68, S96, S98, S105, S106, S108, S113, S114, S129, S157, S172, S174, S214, S221, S222, S227, S240, S245, S246, S250, S251, S271, S272, S276, S278, S281, S294, S348, S383, S384, S400, S401, S409, S410, S412, S437, S438

Psychotic depression…………………………S412

PTSD…………………………S1, S11, S12, S17, S18, S23, S24, S48, S49, S54–S56, S76, S78–S84, S110, S111, S140, S142–S144, S162, S163, S172, S203, S256, S257, S259, S267, S268, S296, S306, S307, S313, S314, S359, S395, S407–S409, S445–S447

Puberty…………………………S146, S200, S219, S406, S407

Punishment…………………………S215, S267, S365

Putamen…………………………S19, S28, S47, S112, S115, S126, S141, S150, S158, S174, S268, S269, S284, S286, S291, S292, S341, S391, S394, S397, S401, S403, S414, S415

Q

QTL…………………………S65, S375

Quetiapine…………………………S65, S98, S99, S105, S127, S128, S170, S172, S173, S175, S176, S184, S274, S302, S343, S354, S425

Quetiapine XR…………………………S99, S101, S170, S173, S343, S344

Quinpirole…………………………S13, S50, S51, S309, S310, S366

R

Rac1…………………………S434

Radioimmunoassay…………………………S110, S139, S166, S167

Randomized controlled trial…………………………S162, S163, S175, S375, S425

Rapid antidepressant…………………………S16, S44, S45, S62, S295, S299, S444

Rapid tryptophan depletion…………………………S76, S136

Rat…………………………S1, S6, S9, S13–S19, S22, S35–S37, S44, S47, S50, S53, S55, S56, S58, S62, S66, S68, S73, S75, S76, S78, S78–S81, S83, S84, S87, S107, S151, S152, S159, S167, S182–S191, S193, S204, S199–S201, S203–S205, S209–S216, S230, S254, S274, S287, S289, S295, S305–S314, S316, S317, S319, S320, S322–S334, S336–S342, S363, S366, S372–S374, S382, S392, S422, S430–S440, S442–S444, S446–S448

Rater training…………………………S231

RCT…………………………S105, S106, S173, S304, S417, S418

Receptor…………………………S6–S9, S13, S16, S17, S19–S21, S23, S24, S29, S30, S34, S37–S46, S49, S50, S53–S55, S58, S59, S62, S65, S67, S70, S71, S73, S76, S79, S81–S83, S85–S88, S90, S97, S98, S107, S122, S124–S126, S132–S134, S157, S159, S164, S166, S171, S178–S187, S189–S195, S199, S200, S204, S208, S210, S211, S216–S219, S224, S225, S233–S235, S237, S254, S256–S263, S266, S268, S269, S274, S276, S279, S280, S283, S284, S286, S291, S292, S295, S302, S304, S305, S307–S312, S317, S319, S327–S339, S342, S357, S364, S366, S373, S375, S378–S380, S382, S383, S392, S393, S397, S402, S403, S405, S406, S409, S415, S427, S428, S431, S432, S434–S436, S438–S441, S443, S448

Receptor reserve…………………………S181, S182

Recruitment…………………………S12, S28, S70, S87, S163, S166, S186, S187, S216, S349, S360, S366, S387, S404, S413

Recurrent depression…………………………S229

Regulation…………………………S3, S15–S19, S21, S23, S24, S42, S45, S48, S49, S55, S57–S59, S68, S69, S73, S77, S82, S84, S86, S87, S89, S92, S94, S109–S111, S113, S119, S135, S140, S142, S144, S148, S153, S158, S160, S163–S166, S178, S184, S190, S194–S196, S202, S204, S211, S212, S214, S233, S234, S257, S262, S270, S290, S293, S307, S315, S318, S321, S325, S327, S333, S336, S339, S341, S372, S374, S385, S390, S392, S400–S402, S405, S406, S410, S418, S422, S430, S434, S443, S445, S448, S449

Reinforcement…………………………S7, S9, S13, S28, S36, S79, S83, S126, S189, S192, S211, S215–S217, S242, S286, S325, S328, S330–S332, S338, S339, S364, S365, S372–S374, S380, S442, S448

Reinstatement…………………………S6, S13–S15, S36, S50, S81, S179, S190, S191, S193, S194, S211, S312, S322, S326–S328, S330–S332, S339, S363, S440, S441

Rejection…………………………S112, S392, S393

Relapse…………………………S6, S7, S13–S15, S20, S35, S36, S65, S76, S101, S102, S105, S106, S162, S165, S166, S178, S179, S188, S189, S211, S230, S265, S284, S285, S289, S290, S300, S306, S311, S315, S322, S326–S329, S331, S339, S347, S357, S374, S377–S379, S403, S405, S412, S420, S442, S443

Relapse prevention…………………………S101, S377

Remission…………………………S62, S119, S166, S168, S172, S176, S201, S205, S225, S229, S239, S245, S246, S252, S297, S298, S300–S304, S315, S347, S352, S353, S356, S357, S381, S394, S411, S412, S417, S419–S424, S432, S434

Reproduction…………………………S248

Residual symptoms…………………………S265, S351, S421

Resilience…………………………S4, S11, S23, S24, S48, S54, S56, S82, S85, S200, S201, S203, S204, S257, S327, S363

Response…………………………S1, S3–S5, S7, S8, S12, S13, S15, S18, S19, S22–S24, S28, S33, S35, S37–S39, S41, S43, S45, S47, S48, S52, S53, S55–S57, S59, S62–S66, S69, S73, S75–S77, S79–S84, S86–S88, S93–S95, S101–S103, S105, S106, S108–S115, S119, S121, S123–S126, S132, S133, S135–S137, S139–S141, S143–S145, S147, S151–S153, S159, S160, S162, S163, S165, S166, S174, S176–S179, S181–S185, S187, S191, S192, S196, S197, S199, S201–S206, S209, S211, S212, S216, S224–S226, S228, S230, S231, S235, S239, S242, S246–S248, S250, S251, S253, S254, S257, S262–S264, S266, S269–S272, S276, S278–S280, S282–S284, S286, S287, S289–S291, S295–S298, S300–S304, S307, S309, S312, S315–S319, S321, S322, S325–S331, S335–S340, S343–S346, S348, S349, S352–S357, S361–S367, S369, S373–S375, S378, S380, S382, S384, S386, S392, S395, S401–S407, S409–S413, S415–S417, S422–S426, S430–S432, S436, S438, S443, S446, S447, S448

Response control…………………………S112

Response inhibition…………………………S3, S50, S54, S55, S66, S108, S109, S112, S123, S158, S283, S284, S286, S366

Resting state…………………………S110, S148, S149, S154, S265, S270, S271, S400

Resting state connectivity…………………………S33

Resting State fMRI…………………………S148, S150, S157, S270, S277, S398

Resting state functional connectivity…………………………S148, S149, S238, S270, S277

Reuptake…………………………S19, S45, S58, S75, S79, S80, S82, S83, S87, S120, S122, S124, S139, S143, S187, S188, S201, S205, S206, S225, S226, S253, S265, S266, S284, S294, S296, S297, S302, S307, S310, S311, S314, S344, S346, S357, S384, S417, S430, S431, S434, S443, S447

Reward…………………………S6, S9, S15, S19, S20, S27, S28, S35, S36, S41, S47, S48, S52, S68, S81, S82, S92, S95, S112, S115, S126, S139, S145, S164, S165, S179, S190, S191, S193, S196, S197, S200, S201, S215–S217, S239, S242, S261, S265, S267, S272, S273, S289–S291, S308–S310, S312, S316, S321, S322, S324, S328, S331, S334, S336, S339, S363, S364, S367, S375, S380, S391, S405, S415, S416, S427, S429, S433, S441–S444

Reward deficiency…………………………S291, S292

Reward processing…………………………S41, S49, S112, S146, S165, S179, S205, S272, S273, S289–S291, S440

Rhesus…………………………S13, S31, S48, S146, S148, S189, S192, S204, S231, S288, S319, S326, S340, S373, S436

Rhesus macaques…………………………S321, S326, S364, S373

Right inferior frontal gyrus…………………………S149, S255, S388, S391, S392

Riluzole…………………………S44, S139, S140, S229, S299, S300

Rimonabant…………………………S95

Risk…………………………S4, S9–S11, S14, S20, S22–S27, S29, S30, S40, S42, S43, S45, S48–S52, S54, S60–S64, S66, S68–S71, S73, S78, S90, S93, S95, S97, S98, S101, S102, S104, S105, S109, S111, S112, S118–S123, S125, S126, S129–S133, S135–S137, S141, S142, S145, S148, S151, S156, S160, S161, S163, S166, S168, S175–S179, S185, S195, S198, S200–S202, S204, S208–S211, S215, S216, S222, S230, S232, S233, S237, S238, S240–S242, S245, S246, S250–S252, S254, S257, S258, S260–S265, S267, S271–S274, S277–S279, S283, S285, S290, S291, S297, S298, S300, S301, S307, S310, S314–S317, S326, S337, S349, S355, S357, S359, S366–S373, S375, S377, S380, S381, S383, S384, S387, S390, S391, S396, S398, S401, S402, S404, S405, S407–S410, S420, S425, S434, S437, S439, S441, S443–S448

Risk behavior…………………………S366

Risk factors…………………………S23, S24, S28, S44, S49, S63, S69, S70, S119, S121, S129, S137, S175, S219, S222, S237, S251, S283, S315, S341, S368, S370, S371, S377, S425, S427

Risk-taking…………………………S49, S50, S92, S145, S215, S238, S267, S308, S316, S367, S393

Risperidone…………………………S34, S58, S65, S72, S98, S105, S120, S121, S167, S170, S172, S173, S175, S176, S187, S228, S258, S275, S382, S425, S435, S439

Risperidone long-acting injection…………………………S167

Ritalin…………………………S75

Rivastigmine…………………………S223, S224, S236

RNA sequencing…………………………S26, S336, S374

Rna-seq…………………………S55, S212, S213, S373, S378

Rodent…………………………S14, S23, S36, S38, S58, S59, S76, S80, S92, S107, S151, S172, S200, S212, S215, S216, S288, S289, S304, S309, S311, S327, S334, S382, S416, S437, S438

Romantic love…………………………S406

Rtms…………………………S232, S362, S363, S413

RT-PCR…………………………S8, S88, S91, S210, S334, S337, S342, S373, S383

S

Satiety…………………………S19, S158, S179, S266, S297, S308, S363

SBSS…………………………S82

Schizoaffective disorder…………………………S40, S94, S96, S97, S104–S106, S132, S173–S175, S195, S368, S382, S424

Schizophrenia…………………………S5, S7, S8, S10, S11, S17, S18, S20–S36, S39–S42, S48, S49, S51, S56–S62, S66, S67, S70–S73, S76, S77, S84, S89, S94–S108, S113, S116, S117, S123, S126, S128–S136, S139, S143, S146, S147, S157, S162, S163, S168–S176, S182–S185, S187, S188, S195, S196, S199, S208–S215, S218–S222, S232, S233, S238, S240–S251, S253–S256, S260, S263–S265, S270–S281, S284, S292–S294, S303, S317, S319–S321, S336, S337, S344, S362, S368, S371, S375, S381–S386, S394, S395, S400, S406, S409–S411, S415–S418, S424, S431, S433–S438, S444, S446

Schizotypal personality disorder…………………………S269

Scopolamine…………………………S62, S423, S422, S435

Screening…………………………S37, S56, S90, S100, S107, S128, S129, S153, S161, S163, S170, S186, S198, S207, S220, S224, S225, S230, S232, S252, S263, S285, S287, S288, S291, S303, S310, S353, S357, S369, S394, S408, S437

Secondary prevention…………………………S24, S306

Second-generation antipsychotic…………………………S34, S114, S184, S382

Sedation…………………………S181, S180, S183, S184, S290, S324, S403, S422, S428

Segmentation…………………………S145, S149, S156, S390, S394

Seizure…………………………S56, S200, S208, S230, S231, S329, S386, S399, S400, S410, S411, S413

Seizure threshold…………………………S85, S386, S410–S412

Selegiline transdermal system…………………………S229, S230, S348

Self-administration…………………………S6, S35, S50, S81, S178, S189–S194, S211, S216, S311, S322, S324, S325, S327–S330, S332–S334, S338, S339, S342, S365, S372–S374, S429, S430, S441, S442

Self-awareness…………………………S245, S246

Self-compassion…………………………S162

Self-report…………………………S49, S137, S149, S158, S163, S165, S181, S225, S241, S249, S250, S256, S259, S263, S288, S291, S294, S316, S351, S367, S371, S376, S386, S416, S429

Semantic priming…………………………S279

Sensitization…………………………S50, S54, S76, S159, S164, S169, S191, S217, S308, S330, S334, S384

Sensorimotor gating…………………………S76, S79, S169

Sensory gating…………………………S98, S198, S240

Serine racemase…………………………S208, S214

Serotonin…………………………S19, S45, S56, S59, S60, S62, S76, S79, S82, S83, S85–S88, S118, S120, S122, S124, S125, S128, S130, S132, S133, S136, S139, S182, S184, S189, S201, S202, S205, S206, S210, S224, S225, S253, S265, S266, S282, S294, S297, S306, S307, S311, S314, S319, S326, S329, S335, S344, S346, S357, S374, S376, S397, S409, S417, S422, S430, S431, S434, S435, S442, S447, S448

Serotonin 2C receptor…………………………S310

Serotonin syndrome…………………………S206

Serotonin transporter…………………………S60, S83, S86, S132, S142, S146, S206, S260, S265, S266, S282, S340, S377

SERT…………………………S4, S60, S83, S86, S131, S206, S260, S282, S376, S422, S430

Set shifting…………………………S75, S83, S182, S187, S188, S214, S215, S319, S320

Severe…………………………S24, S54, S95, S105, S106, S112–S114, S121, S127, S128, S149, S153, S166, S172, S204, S228–S230, S232, S235, S250, S255, S266, S277, S295, S299, S310, S313, S320, S348, S357–S359, S369, S384, S385, S387, S403, S407, S414, S420, S422, S425, S429, S444

Severe mood dysregulation…………………………S116, S153, S387

Sex…………………………S6, S14, S20, S23, S26, S55, S56, S70, S87, S105, S113, S122, S128, S145, S148, S156, S161, S176, S177, S215, S221, S238, S241, S254, S255, S257, S264, S265, S271, S277, S279, S280, S313–S316, S337, S357, S359, S362, S366, S369, S376, S378, S381, S384, S385, S389, S391, S393, S398, S413, S428

Sex difference…………………………S6, S55, S275

Sexual dysfunction…………………………S121, S146, S302, S407, S422

SFRP3…………………………S89

Side effect…………………………S85, S122, S132, S135, S187, S307, S311, S312

Signal…………………………S19, S21, S26–S28, S34, S54, S55, S73, S75, S86, S97, S106, S109, S112, S118, S140–S142, S144, S154, S165, S179, S183, S186, S199, S203, S230, S234, S239, S244, S247, S248, S267, S270, S271, S273, S276, S281, S288–S291, S310, S315, S321, S364, S365, S390, S393–S395, S400, S401, S404, S415, S423, S424, S448

Signal detection…………………………S94, S95, S231, S360, S361

Signal transduction…………………………S56, S186, S187, S253, S320, S340, S443

Signalling…………………………S16, S35, S213, S272, S310

Sign-trackers…………………………S199

Simulations…………………………S61, S72, S181, S194, S226, S227, S410

Sk channels…………………………S329

Sleep…………………………S11, S15, S16, S44, S45, S71, S93, S94, S125, S178, S195, S212, S223, S233, S234, S251, S252, S301, S314–S316, S324, S330, S362, S389, S390, S392, S430, S445, S446

Sleep apnea…………………………S251

Sleep deprivation…………………………S15, S16, S212, S223, S362

Sleep EEG…………………………S44, S195, S234, S314

Sleep loss…………………………S16, S223

Sleepiness…………………………S98, S99, S315, S391, S392

Slow-wave activity…………………………S212

Smoking…………………………S6, S13, S20, S26, S50, S93, S98, S151, S164, S165, S175, S176, S178–S180, S243, S251, S277, S284, S285, S287, S290, S326, S368, S374, S375, S377–S380, S403–S405, S428

Smoking cessation…………………………S98, S176, S179, S287, S289, S332, S374, S375, S379–S381, S405, S428

Smoking cue…………………………S165

Smoking cue reactivity…………………………S285

SNP…………………………S15, S21–S23, S29, S42, S46, S51, S52, S61, S65, S122, S126, S130–S133, S135, S136, S180, S222, S238, S239, S253, S255–S259, S262, S263, S265, S283, S284, S293, S337, S368, S369, S373, S375–S380, S383

SNRI…………………………S205, S226, S344

Social vocational outcome…………………………S104

Sociability…………………………S307, S318, S427

Social…………………………S2, S3, S5, S11, S30, S34, S48, S49, S72–S74, S77, S82, S85, S86, S90, S96, S105, S106, S109, S110, S112, S115, S117, S137, S146–S148, S150–S152, S161, S163, S168, S172, S178, S179, S190, S194, S196, S198, S201, S224, S225, S228, S241–S243, S246, S249, S259, S272, S276, S280, S289, S294, S306, S308, S316, S318, S329, S341, S342, S351, S355, S357, S359, S377, S390, S392, S393, S406, S407, S409, S410, S416, S422, S427–S429, S439, S440, S443, S444, S448

Social anhedonia…………………………S241, S242

Social anxiety…………………………S144, S225, S241, S242, S270, S272, S405, S406

Social anxiety disorder…………………………S73, S108, S111, S225, S392, S421

Social behavior…………………………S72, S73, S96, S112, S196, S318, S405

Social cognition…………………………S6, S33, S34, S96, S117, S147, S171, S271, S318, S362, S440

Social defeat…………………………S43, S82, S85, S90, S161, S201, S202, S328, S329, S431, S433, S444

Social evaluation…………………………S112

Social interaction…………………………S82, S112, S152, S160, S202, S225, S256, S258, S260, S341, S444

Social isolation…………………………S81, S88, S258, S443

Social phobia…………………………S110, S111, S141, S225, S250

Social stress…………………………S49, S82, S147, S160, S202, S328, S329, S409

Social withdrawal…………………………S97, S213, S232

Sodium…………………………S308, S418, S445

Somatosensory…………………………S71, S146, S147, S321

Somatostatin…………………………S32, S57, S205, S212, S385

Sox6…………………………S384

Spatial navigation…………………………S268

Spatial processing…………………………S6, S131, S264

SPECT…………………………S20, S231, S386, S399, S398

Spines…………………………S62, S63, S217, S218, S221

SRI…………………………S32, S79, S288, S436

SSR1419415…………………………S351

SSRI…………………………S60, S62, S86, S87, S117, S119, S118, S122, S125, S163, S201, S205, S225, S265, S294–S297, S304, S306, S307, S313, S314, S346, S347, S408, S413, S416, S425, S429, S430

SSRT…………………………S75

Startle…………………………S1, S34, S41, S54, S76–S78, S98, S131, S142, S169, S184, S214, S215, S243, S258, S334, S406, S407, S446, S447, S449

Startle response…………………………S215, S240, S406, S407, S448

Statistical analysis…………………………S51, S91, S116, S146, S153, S157, S289, S314, S345, S361

Steady state…………………………S173, S177, S195, S295, S321, S436

Stem cells…………………………S218, S220, S292, S336, S341

Stereotypy…………………………S184, S198, S199, S333

STG…………………………S150, S154, S157, S240, S241, S365

Stimulant…………………………S7, S13, S82, S192, S285, S375, S377, S378, S380, S426, S427, S432, S442

Stopping…………………………S219, S321, S322

Strain…………………………S54, S75, S77, S81, S205, S213–S216, S327, S334, S340, S448

Strategies…………………………S10, S14, S20, S36, S39, S54, S57, S59, S64–S66, S68, S129, S159, S162, S165, S166, S168, S185, S187, S191, S193, S197, S201, S213, S231, S239, S262, S270, S276, S278, S287, S290, S306, S317, S335, S343, S346, S356, S360, S380, S384, S394, S397, S405, S407, S414, S421, S438, S448

Strattera…………………………S83

Stress…………………………S1, S5, S7, S10, S12, S16, S19, S21–S24, S28, S37–S39, S43, S49, S54–S57, S59, S60, S62, S63, S73, S76–S83, S85–S88, S90, S110, S111, S119, S126, S127, S137, S144–S150, S159–S161, S172, S178, S184, S193, S194, S200–S205, S213, S214, S222, S243, S249, S254, S256–S259, S262–S264, S287, S288, S295, S296, S302, S306, S307, S315, S318, S327–S329, S331, S332, S336, S337, S341, S351, S354, S357, S364, S369, S377, S378, S384, S396–S398, S405–S410, S412, S415, S433, S441, S443, S446, S448

Stress response…………………………S23, S56, S77, S80, S87, S142, S147, S160, S258, S287, S306, S314, S315, S336, S363, S409, S442

Striatum…………………………S9, S10, S19, S20, S28, S47, S52, S68, S75, S82, S84, S109, S112, S115, S145, S150, S152, S154, S155, S161, S192, S199, S206, S207, S213, S216, S238, S258, S264, S267, S271, S272, S285, S286, S289–S291, S305, S306, S310, S311, S319, S329, S338–S340, S362, S365, S379, S384, S386, S391, S393, S397, S398, S403, S405, S415, S416, S448

Stroop…………………………S53, S54, S111, S114, S158, S164, S271, S286, S305, S395

Structural imaging…………………………S23, S267, S387, S391, S394

Structural MRI…………………………S3, S31, S48, S172, S240, S270, S277, S279, S318, S379, S381, S399

Structure…………………………S2, S6, S10, S21, S23, S37, S40, S48, S53, S64, S68, S78, S79, S84, S87, S134, S156, S157, S162, S197, S198, S199, S208, S216, S217, S234, S235, S244, S249, S260, S264, S273–S278, S281, S322, S327, S362, S368, S387, S399, S400, S430, S449

Subgenual…………………………S53, S109, S112, S141, S283, S319, S386, S391, S396

Subgenual cingulate…………………………S161, S318, S396, S400, S401

Subjective cognitive impairment…………………………S236

Subjective effects…………………………S6, S178, S180, S203, S211, S288, S404, S427, S428

Substance abuse…………………………S51, S67, S81, S116, S148, S157, S158, S176, S211, S239, S249, S270, S283, S301, S366, S367, S369–S371, S393, S427, S437, S447

Substance P…………………………S138, S180, S216

Substantia nigra…………………………S10, S130, S158, S190, S199, S203, S258, S269, S281, S291, S305, S329, S402

Subsyndromal comorbid manic symptoms…………………………S418–S420

Subthalamic nucleus…………………………S171, S343

Subtyping…………………………S280

Sucrose…………………………S9, S19, S38, S47, S48, S197, S200, S203, S325, S330, S367, S412, S440–S442, S444

Suicidality…………………………S98, S172, S300, S359, S420

Suicide…………………………S26, S27, S89, S99, S130, S137–S139, S144, S146, S160, S161, S166, S172, S239, S256, S257, S262, S263, S269, S296, S300, S357–S359, S365, S371, S389, S413, S419, S422, S425, S446

Suicide attempt…………………………S130, S139, S262, S357, S359, S365, S371, S423

Suicide intent…………………………S160, S161, S359

Superior longitudinal fasciculus…………………………S147, S157, S244, S399

Surface area…………………………S148, S158

Susceptibility…………………………S10, S21, S43, S46, S56, S61, S63, S70, S71, S84, S86, S113, S124, S126, S132, S134, S145, S198, S201, S202, S208, S210, S213, S238, S250, S251, S260, S274, S283, S327, S336–S338, S375, S395, S404, S445

Sustained attention…………………………S75, S98, S123, S152, S160, S177, S199, S215

Suvorexant…………………………S233, S234

Sweet taste test…………………………S366

Switching…………………………S42, S156, S168, S175, S228, S322, S356, S417, S425, S448

Synapse…………………………S30, S39, S40, S62, S68, S84, S88, S221, S293, S319, S325, S338, S341

Synapsin…………………………S62, S372, S439, S445

Synaptic plasticity…………………………S7, S16, S39, S40, S44, S62, S67, S77, S81, S184, S212, S213, S268, S325, S329, S338, S341, S372, S374, S412, S438, S443, S447, S448

Synaptogenesis…………………………S17, S30, S44, S62, S63, S78, S210, S337

Synthetic cathinone…………………………S440, S441

System XC…………………………S190, S319, S320

T

TAAR1…………………………S339, S340, S435, S436, S440

Tail-suspension…………………………S205, S310, S432

Tamper resistant formulations…………………………S166

Tat…………………………S392

TBI…………………………S43, S268, S269, S291, S292, S407, S408

TC-5619…………………………S98

Temperament…………………………S78, S109, S112, S204, S256

Temperature…………………………S181, S206, S317, S430, S442, S449

Testosterone…………………………S55, S257, S315, S324, S386, S408

TG2…………………………S433

Thalamus…………………………S20, S51, S58, S126, S145, S146, S150, S157, S158, S161, S162, S174, S180, S203, S238, S246, S258, S266, S267, S278, S286, S288, S318, S340, S345, S364, S365, S393, S394, S403, S415, S416, S448

Therapeutics…………………………S12, S17, S36, S37, S43, S53, S76, S98, S106, S107, S127, S168, S176, S201, S211, S216, S218, S219, S228, S230, S240, S242, S247, S253, S257, S259, S270, S276, S286, S291, S297, S304, S311, S325, S340, S344, S348–S350, S379, S380, S382, S393, S394, S414, S416, S417, S421, S434, S438, S443, S446, S447

Thyroid hormone…………………………S161, S441

Time estimation…………………………S379

Timing…………………………S7, S41, S55, S62, S163, S210, S211, S321

TLR…………………………S342

TLR4…………………………S164, S342

TMS…………………………S27, S232, S362, S363, S413

Tobacco…………………………S6, S7, S50, S98, S99, S164, S179, S180, S191, S251, S287, S326, S332, S369, S372, S379, S380, S404

Tobacco addiction…………………………S175, S176, S332, S372, S373

Tolerance…………………………S14, S76, S121, S178, S184, S208, S215, S308, S324, S326

Top-down control…………………………S199, S209, S285

Topiramate…………………………S114, S342, S343, S404

Tourette syndrome…………………………S198, S232, S254, S259, S268

Toxoplasma gondii…………………………S242

Trace amines…………………………S435, S440

Tramadol…………………………S37, S206

Transcranial magnetic stimulation…………………………S165, S232, S362

Transcription…………………………S2, S15, S19, S23, S27, S59, S62, S71, S86, S132, S135, S202, S207, S222, S254, S263, S264, S293, S305, S307, S325, S331, S336–S338, S342, S373, S374, S385

Trans-generational…………………………S202

Transgenic mouse…………………………S13, S43, S64, S207, S217, S257, S305

Transient…………………………S17, S50, S66, S73, S83, S88, S108, S120, S195, S197, S203, S216, S227, S253, S299, S310, S318, S319, S321, S325, S339, S446, S449

Translational science…………………………S12, S25

Transporter…………………………S9, S19, S21, S39, S80, S83, S85, S86, S108, S188, S190, S197, S200, S211, S224, S225, S282, S307, S338–S340, S344, S384, S430, S435

Trauma…………………………S1, S11, S24, S48, S49, S54, S76, S78, S82, S111, S140, S142, S149, S250, S256, S257, S263, S287, S288, S296, S314, S371, S408–S410

Traumatic brain injury…………………………S56, S115, S267, S268, S291, S292, S407

Treatment…………………………S2, S3, S5–S7, S9, S11, S13, S14, S16, S18, S22–S25, S28, S30, S35, S38–S40, S44, S48, S50, S52, S55, S57, S58, S60, S64–S66, S69, S70, S73, S75, S77–S79, S82–S86, S88–S92, S94–S108, S110, S111, S114–S116, S118, S120–S122, S124, S125, S127–S129, S132, S133, S135, S136, S138–S140, S143, S145, S151–S153, S159, S161–S180, S182–S185, S187–S194, S199–S210, S212–S215, S217, S220, S223–S235, S237, S241–S243, S247, S250–S253, S260, S261, S265–S267, S269, S272, S274–S276, S281, S284, S289, S290, S294–S308, S310, S312–S314, S317, S319, S321–S323, S325, S327, S329–S332, S334–S336, S338, S340, S341, S343–S360, S366, S367, S369, S371, S372, S374–S376, S378–S380, S382, S384–S387, S390–S396, S399, S401–S403, S405, S409, S411–S415, S417–S428, S430–S441, S443, S444, S448

Treatment prediction…………………………S394

Treatment resistance…………………………S39

Treatment resistant…………………………S34, S37, S39, S72, S166, S172

Treatment resistant depression…………………………S12, S18, S37, S39, S65, S90, S121, S205, S356, S386

Treatment response…………………………S3, S23, S65, S102, S105, S110, S117, S121, S133, S139, S140, S159, S164, S221, S246, S265, S297, S298, S301, S302, S304, S343, S352, S386, S387, S402, S418, S423, S424, S426, S431

Treatment-seeking alcoholics…………………………S283, S371

Treatments…………………………S1, S2, S4, S5, S11, S12, S14, S15, S25, S40, S41, S43, S52, S59, S63, S66, S69, S79, S95, S96, S99, S100, S104, S107, S109, S118, S122, S126, S128, S132, S140, S164, S170, S175, S176, S180, S185, S191, S194, S198, S200, S201, S210, S215, S217, S225, S231, S232, S234, S238, S253, S261, S266, S276, S285, S290, S294, S297, S299, S302, S304, S308, S309, S312, S313, S324, S331, S342, S345, S346, S349, S350, S354, S360, S381, S386, S393, S394, S399, S402, S411, S412, S415, S418, S422, S424, S425, S431–S434, S439, S447

Treatment-seeking alcoholics…………………………S283

Trka…………………………S124

Trkb…………………………S45, S124, S208, S258, S433

TRP channel…………………………S447, S448

TRPV1…………………………S309, S310

Tryptophan…………………………S38, S60, S76, S135, S136, S209, S300

Tryptophan hydroxylase…………………………S127

TTC12…………………………S377

Tyramine…………………………S298

U

U99194…………………………S183

Unaffected siblings…………………………S90, S122, S123, S278, S279, S400, S401

Unconscious…………………………S403

Unemployment…………………………S166, S368, S369

Up-states…………………………S194V

V1b receptor…………………………S351

Val66met…………………………S127, S149

Val66Met…………………………S253

Validation…………………………S11, S20, S22, S24, S25, S31, S37, S51, S66, S98, S131, S133, S159, S167, S193, S202, S212, S213, S222, S252, S253, S259, S293, S346, S385, S417, S421

Valproate…………………………S207, S349, S359, S422, S423

Varenicline…………………………S97, S98, S179, S368, S374

Variability…………………………S4, S5, S11, S20, S27, S54, S58, S65, S72, S85, S93, S110, S111, S112, S132, S138, S152, S172, S176, S221, S227, S231, S238, S239, S263, S267, S270, S290, S292, S314, S360, S375, S390, S395, S409, S410, S418, S434

Vascular disease…………………………S250

Vasopressin…………………………S138, S151, S166, S351, S361, S408

Velocardiofacial syndrome…………………………S270

Venlafaxine…………………………S3, S226, S296

Venous plasma nicotine…………………………S404

Ventral hippocampus…………………………S211

Ventral striatum…………………………S28, S48, S115, S155, S157, S177, S216, S238, S239, S266, S272, S276, S277, S285, S287, S289, S290, S291, S365, S379, S387, S392, S395, S402, S404

Ventral tegmental area…………………………S6, S9, S15, S19, S36, S73, S75, S78, S92, S164, S192, S197, S203, S205, S272, S305, S325, S327, S330, S332, S337, S340, S396, S431, S434, S437, S441, S444, S448

Ventromedial prefrontal cortex…………………………S48, S141, S143, S164, S271, S365, S368

Veteran…………………………S23, S96, S100, S110, S111, S131, S140, S143, S162, S163, S247, S248, S256, S265, S267, S268, S284, S295, S313, S355, S367, S381, S408, S446

VGlut…………………………S203

Vilazodone…………………………S357

Violence…………………………S122, S139, S160, S371, S441

Viral load…………………………S304, S305

Viral vector…………………………S9, S14, S19, S331, S432

VMAT1…………………………S211, S212

Voltammetry…………………………S73, S363

Volunteers…………………………S37, S41, S58, S67, S98, S144, S149, S158, S160, S169, S177, S180, S235, S244, S246, S254, S267, S269, S276, S279, S290, S293, S296, S299, S317, S383, S387, S392, S395, S398, S401, S413, S427, S428, S436

Voxel based morphometry…………………………S28, S391, S393

VTA…………………………S6, S15, S36, S73, S78, S92, S164, S196, S197, S203, S272, S309, S322, S325, S327, S328, S330–S332, S334, S431–S433, S440, S442, S443

Vulnerability…………………………S4, S10–S12, S15, S19, S21, S23, S24, S41, S48–S50, S69, S82, S83, S85, S95, S109, S123–S125, S130, S144, S149, S157, S176, S206, S211, S238, S244, S250, S254, S257, S261, S271, S274, S278, S279, S284, S287, S288, S308, S314, S315, S327, S328, S330, S331, S333, S337, S339, S376, S377, S383, S384, S391, S392, S410, S440, S441

W

Wanting…………………………S28, S365, S366

Weight…………………………S47, S65, S101–S103, S107, S121, S132, S133, S136, S148, S158, S167–S169, S173–S176, S186, S200, S201, S220, S228, S261, S265, S266, S268, S291, S297, S303, S311, S312, S326, S329, S350, S393, S425, S428, S439, S441

Weight gain…………………………S9, S64, S65, S72, S88, S103, S107, S121, S132, S133, S158, S169, S173, S174, S176, S186, S291, S297, S302, S303, S329, S349, S350, S428, S439, S440

Weight loss…………………………S88, S174, S266

White matter…………………………S5, S10, S32, S34, S37, S68, S91, S146–S149, S152–S154, S156, S192, S222, S243, S244, S268, S272, S275, S277, S278, S280–S282, S288, S336, S362, S390, S393, S394, S396–S399, S401

Widespread pain…………………………S235

Williams syndrome…………………………S73, S156

Withdrawal…………………………S19, S47, S50, S94, S96, S100, S111, , S176, S179, S188, S192, S194, S204, S213, S217, S228, S232, S285, S289, S296, S305, S306, S313, S316, S322, S324, S329, S331–S334, S340, S341, S350, S366, S368, S369, S372–S374, S409, S426, S427

Women…………………………S7, S9, S10, S31, S47, S48, S55, S93, S120, S128, S130, S135, S140, S142, S145, S146, S159, S162, S163, S196, S200, S201, S235, S236, S255, S261, S266, S268, S275, S284, S285, S288, S297, S298, S313–S317, S328, S347, S371, S378, S390, S396, S397, S404, S406, S408, S415, S422, S426–S428

Working memory…………………………S3, S5, S6, S10, S21–S23, S32–S35, S49, S71, S72, S98, S106, S107, S114, S117, S118, S123, S134, S135, S147, S152, S156, S171, S172, S174, S177, S209, S210, S215, S236, S237, S248, S270, S274, S276, S277, S279, S281, S286, S313, S320, S351, S362, S363, S366, S423, S424, S434

Working model of the child interview…………………………S118

X

X-linked…………………………S46, S134

Y

Yohimbine…………………………S76, S193, S253, S308, S309, S317

Z

Zebrafish…………………………S198, S207

Ziprasidone…………………………S65, S105, S127, S175, S184, S255, S422

ZNF804…………………………S337, S338, S368